<SEC-DOCUMENT>0001104659-23-095334-index.html : 20230825
<SEC-HEADER>0001104659-23-095334.hdr.sgml : 20230825
<ACCEPTANCE-DATETIME>20230825161541
ACCESSION NUMBER:		0001104659-23-095334
CONFORMED SUBMISSION TYPE:	SC 13G
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20230825
DATE AS OF CHANGE:		20230825
GROUP MEMBERS:		DR. SRINIVAS AKKARAJU
GROUP MEMBERS:		SAMSARA BIOCAPITAL GP, LLC

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Lyra Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001327273
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-91508
		FILM NUMBER:		231208452

	BUSINESS ADDRESS:	
		STREET 1:		480 ARSENAL WAY
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
		BUSINESS PHONE:		617-373-4600

	MAIL ADDRESS:	
		STREET 1:		480 ARSENAL WAY
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	480 Biomedical, Inc.
		DATE OF NAME CHANGE:	20120927

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Arsenal Vascular, Inc.
		DATE OF NAME CHANGE:	20110826

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Arsenal Medical, Inc.
		DATE OF NAME CHANGE:	20090414

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Samsara BioCapital, L.P.
		CENTRAL INDEX KEY:			0001699737
		IRS NUMBER:				813958301
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G

	BUSINESS ADDRESS:	
		STREET 1:		628 MIDDLEFIELD ROAD
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94301
		BUSINESS PHONE:		(650) 285-4270

	MAIL ADDRESS:	
		STREET 1:		628 MIDDLEFIELD ROAD
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94301
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G
<SEQUENCE>1
<FILENAME>tm2324791d1_sc13g.htm
<DESCRIPTION>SC 13G
<TEXT>
Document 1 - file: tm2324791d1_sc13g.htm

</DOCUMENT>
</SEC-DOCUMENT>