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Leases - Additional Information (Details) $ in Thousands |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | --- | --- | ---
Jul. 31, 2023 USD ($) | Dec. 31, 2023 USD ($) ft² | May 31, 2022 USD ($) ft² | Sep. 30, 2025 USD ($) | Sep. 30, 2024 USD ($) | Sep. 30, 2025 USD ($) Lease | Sep. 30, 2024 USD ($) | Dec. 31, 2024 USD ($)
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Restricted cash |  |  |  | $ 1,993 |  | $ 1,993 |  | $ 1,993
Lessee, Operating Lease, Option to Extend |  |  | one additional five-year term |  |  |  |  |
Impairment of right-of-use assets |  |  |  | 0 | $ 0 | 0 | $ 22,836 | $ 22,800
Operating lease cost |  |  |  | $ 1,276 | $ 1,346 | $ 3,877 | $ 5,082 |
Number of leased properties marketed for sublease arrangements | Lease |  |  |  |  |  | 3 |  |
Watertown Lease |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Extended lease term | 2027-04 |  |  |  |  |  |  |
Lessee, Operating Lease, Existence of Option to Extend [true false] |  |  |  |  |  | true |  |
Waltham Lease |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Number of leases | Lease |  |  |  |  |  | 2 |  |
Office and Laboratory | Waltham Lease |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Initial base rent |  |  | $ 2,200 |  |  |  |  |
Area of property | ft² |  |  | 29,000 |  |  |  |  |
Percentage of annual rent increment |  |  | 3.00% |  |  |  |  |
Office and Laboratory | Waltham Sublease |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Initial base rent |  | $ 1,800 |  |  |  |  |  |
Area of property | ft² |  | 24,000 |  |  |  |  |  |
Percentage of annual rent increment |  | 3.00% |  |  |  |  |  |
Certificate of Deposits | Watertown Lease |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Restricted cash | $ 300 |  |  |  |  |  |  |
Letter of Credit | Watertown Lease |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Restricted cash | $ 300 |  |  |  |  |  |  |
Letter of Credit | Waltham Lease |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Restricted cash |  |  | $ 1,100 |  |  |  |  |
Letter of Credit | Waltham Sublease |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Restricted cash |  | $ 600 |  |  |  |  |  |

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