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v3.25.3

Segment Reporting (Tables) | 9 Months Ended
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Sep. 30, 2025
Segment Reporting [Abstract] |
Summary of Revenue Significant Expenses and Net Loss for Segment | The following table presents revenue, significant expenses and net loss for the Company's segment (in thousands):
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2025 |  |  | 2024 |  |  | 2025 |  |  | 2024 |
Collaboration revenue |  | $ | 25 |  |  | $ | 195 |  |  | $ | 391 |  |  | $ | 1,325 |
Operating expenses: |  |  |  |  |  |  |  |  |  |  |  |
Clinical related costs |  |  | 90 |  |  |  | 2,186 |  |  |  | 2,722 |  |  |  | 13,204 |
Employee related costs |  |  | 2,069 |  |  |  | 3,738 |  |  |  | 8,218 |  |  |  | 18,665 |
Product development and manufacturing costs |  |  | 240 |  |  |  | 161 |  |  |  | 549 |  |  |  | 3,059 |
Facilities, support costs and depreciation |  |  | 2,639 |  |  |  | 2,915 |  |  |  | 7,980 |  |  |  | 10,688 |
Professional, consulting and public company costs |  |  | 1,245 |  |  |  | 833 |  |  |  | 3,564 |  |  |  | 6,676 |
Impairment of property and equipment |  |  | — |  |  |  | — |  |  |  | — |  |  |  | 1,883 |
Impairment of right-of-use assets |  |  | — |  |  |  | — |  |  |  | — |  |  |  | 22,836 |
Restructuring and other related charges |  |  | (21 | ) |  |  | 2,804 |  |  |  | 1,262 |  |  |  | 9,254 |
Total operating expenses |  |  | 6,262 |  |  |  | 12,637 |  |  |  | 24,295 |  |  |  | 86,265 |
Loss from operations |  |  | (6,237 | ) |  |  | (12,442 | ) |  |  | (23,904 | ) |  |  | (84,940 | )
Other income: |  |  |  |  |  |  |  |  |  |  |  |
Interest income |  |  | 256 |  |  |  | 576 |  |  |  | 964 |  |  |  | 2,517 |
Other income |  |  | — |  |  |  | — |  |  |  | 981 |  |  |  | — |
Total other income |  |  | 256 |  |  |  | 576 |  |  |  | 1,945 |  |  |  | 2,517 |
Loss before income tax expense |  |  | (5,981 | ) |  |  | (11,866 | ) |  |  | (21,959 | ) |  |  | (82,423 | )
Income tax expense |  |  | (3 | ) |  |  | (7 | ) |  |  | (9 | ) |  |  | (33 | )
Net loss |  | $ | (5,984 | ) |  | $ | (11,873 | ) |  | $ | (21,968 | ) |  | $ | (82,456 | )

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- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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