    <SEC-DOCUMENT>0001213900-21-005637-index.html : 20210201
    <SEC-HEADER>0001213900-21-005637.hdr.sgml : 20210201
    <ACCEPTANCE-DATETIME>20210201115211
    ACCESSION NUMBER:		0001213900-21-005637
    CONFORMED SUBMISSION TYPE:	424B4
    PUBLIC DOCUMENT COUNT:		15
    FILED AS OF DATE:		20210201
    DATE AS OF CHANGE:		20210201

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			NLS Pharmaceutics Ltd.
    		CENTRAL INDEX KEY:			0001783036
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			V8
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		424B4
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-236797
    		FILM NUMBER:		21575552

    	BUSINESS ADDRESS:
    		STREET 1:		ALTER POSTPLATZ 2
    		CITY:			STANS
    		STATE:			V8
    		ZIP:			CH-6370
    		BUSINESS PHONE:		41-41-618-80-00

    	MAIL ADDRESS:
    		STREET 1:		ALTER POSTPLATZ 2
    		CITY:			STANS
    		STATE:			V8
    		ZIP:			CH-6370
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>424B4
    <SEQUENCE>1
    <FILENAME>ea134268-424b4_nlspharma.htm
    <DESCRIPTION>PROSPECTUS
    <TEXT>
    Document 1 - file: ea134268-424b4_nlspharma.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>image_001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: image_001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>image_004a.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: image_004a.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>image_005.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: image_005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>image_006.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: image_006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>image_007.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: image_007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>image_008.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: image_008.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>image_009.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: image_009.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>image_010.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: image_010.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>image_011.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: image_011.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>image_012.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: image_012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>image_013.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: image_013.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>image_014.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: image_014.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>image_015.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: image_015.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>image_016.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 15 - file: image_016.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>