<SEC-DOCUMENT>0001213900-25-089523-index.html : 20250919
<SEC-HEADER>0001213900-25-089523.hdr.sgml : 20250919
<ACCEPTANCE-DATETIME>20250919160203
ACCESSION NUMBER:		0001213900-25-089523
CONFORMED SUBMISSION TYPE:	6-K
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20250919
FILED AS OF DATE:		20250919
DATE AS OF CHANGE:		20250919

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NLS Pharmaceutics Ltd.
		CENTRAL INDEX KEY:			0001783036
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			V8
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		6-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39957
		FILM NUMBER:		251326796

	BUSINESS ADDRESS:	
		ADDRESS IS A NON US LOCATION: 	YES
		STREET 1:		THE CIRCLE 6
		STREET 2:		8058
		CITY:			ZURICH
		PROVINCE COUNTRY:   	V8
		BUSINESS PHONE:		41-41-618-80-00

	MAIL ADDRESS:	
		ADDRESS IS A NON US LOCATION: 	YES
		STREET 1:		THE CIRCLE 6
		STREET 2:		8058
		CITY:			ZURICH
		PROVINCE COUNTRY:   	V8
</SEC-HEADER>
<DOCUMENT>
<TYPE>6-K
<SEQUENCE>1
<FILENAME>ea0258051-6k_nlspharma.htm
<DESCRIPTION>REPORT OF FOREIGN PRIVATE ISSUER
<TEXT>
Document 1 - file: ea0258051-6k_nlspharma.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-16.1
<SEQUENCE>2
<FILENAME>ea025805101ex16-1_nlspharma.htm
<DESCRIPTION>LETTER FROM MARCUM LLP ADDRESSED TO THE U.S. SECURITIES AND EXCHANGE COMMISSION DATED SEPTEMBER 19, 2025
<TEXT>
Document 2 - file: ea025805101ex16-1_nlspharma.htm

</DOCUMENT>
</SEC-DOCUMENT>