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Related Party Transactions (Details Narrative) - USD ($)		3 Months Ended
	Nov. 29, 2021	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021	Dec. 09, 2021	Oct. 08, 2021	Jul. 15, 2016
Related Party Transaction [Line Items]
Expense reimbursements		$ 0	$ 100,000
Loss contingency, receivable		$ 11,300,000
Legal settlements receivable percentage		50.00%
Litigation settlement, expense	$ 22,500,000
Debt instrument interest rate percentage		6.00%
Accounts receivable, related parties, current		$ 8,686,000		$ 8,647,000
Accounts receivable, related parties, noncurrent		2,813,000		2,813,000
Biofrontera Pharma GmbH [Member] | License and Supply Agreement [Member]
Related Party Transaction [Line Items]
Related party costs		5,200,000	3,000,000.0
Accounts payable related parties		300,000		300,000
Biofrontera Pharma GmbH [Member] | License and Supply Agreement [Member] | Minimum [Member]
Related Party Transaction [Line Items]
Transfer price per unit increment percentage							35.00%
Biofrontera Pharma GmbH [Member] | License and Supply Agreement [Member] | Maximum [Member]
Related Party Transaction [Line Items]
Transfer price per unit increment percentage							50.00%
Biofrontera Pharma for Ameluz [Member] | Minimum [Member]
Related Party Transaction [Line Items]
Purchase price per unit percentage						30.00%
Biofrontera Pharma for Ameluz [Member] | Maximum [Member]
Related Party Transaction [Line Items]
Purchase price per unit percentage						50.00%
Biofrontera AG [Member]
Related Party Transaction [Line Items]
Accounts receivable, related parties		11,300,000
Loss contingency, receivable	11,300,000	11,300,000
Litigation settlement, expense	$ 22,500,000	$ 22,500,000
Debt instrument interest rate percentage		6.00%
Accrued interest		$ 56,000
Accounts receivable, related parties, current		8,500,000			$ 8,400,000
Accounts receivable, related parties, noncurrent		2,800,000
Biofrontera AG [Member] | 2021 Service Agreement [Member]
Related Party Transaction [Line Items]
Related Party Transaction, Selling, General and Administrative Expenses from Transactions with Related Party		100,000	200,000
Biofrontera AG [Member] | Service Agreement [Member]
Related Party Transaction [Line Items]
Accounts payable related parties				200,000
Bioscience [Member]
Related Party Transaction [Line Items]
Expense reimbursements		100,000	100,000
Bioscience [Member] | Clinica Lamp Lease Agreement [Member]
Related Party Transaction [Line Items]
Revenues		15,000	$ 13,000
Accounts receivable, related parties		99,000		92,000
Maruho Co Ltd [Member] | Cutanea Acquisition Agreement [Member]
Related Party Transaction [Line Items]
Accounts receivable, related parties		$ 56,000		$ 56,000

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