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Commitments and Contingencies (Details Narrative) - USD ($)		3 Months Ended
	Nov. 29, 2021	Mar. 31, 2022	Mar. 31, 2021
Loss Contingencies [Line Items]
Settlement agreement term description	the Company entered into a settlement and release agreement with respect to a lawsuit filed March 23, 2018	aggregate settlement amount, plus interest accrued at a rate equal to the weekly average one-year constant maturity Treasury yield and agreed to pay in three annual installments.
Litigation settlement, expense	$ 22,500,000
Settlement amount	11,250,000
Legal settlement liability		$ 11,300,000
Loss Contingency, Receivable		11,300,000
First Installment [Member]
Loss Contingencies [Line Items]
Settlement amount	11,300,000
Xepi LSA [Member]
Loss Contingencies [Line Items]
Annual net sales		2,000,000	$ 4,000,000
Xepi LSA [Member] | Maximum [Member]
Loss Contingencies [Line Items]
Revenues		25,000,000	50,000,000
Maruho Co Ltd [Member] | December 31, 2022 [Member]
Loss Contingencies [Line Items]
Repayments of related party debt		3,600,000
Maruho Co Ltd [Member] | December 31, 2023 [Member]
Loss Contingencies [Line Items]
Repayments of related party debt		3,700,000
Biofrontera AG [Member] | First Installment [Member]
Loss Contingencies [Line Items]
Settlement amount	$ 5,600,000
Facility Leases [Member]
Loss Contingencies [Line Items]
Security deposit		100,000
Rent expense		$ 100,000	200,000
Auto Leases [Member]
Loss Contingencies [Line Items]
Lease payment term		40 months
Lease expense		$ 100,000	$ 100,000

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