<SEC-DOCUMENT>0001209191-15-040767.txt : 20150508
<SEC-HEADER>0001209191-15-040767.hdr.sgml : 20150508
<ACCEPTANCE-DATETIME>20150508185005
ACCESSION NUMBER:		0001209191-15-040767
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20150506
FILED AS OF DATE:		20150508
DATE AS OF CHANGE:		20150508

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Onconova Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001130598
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		375 PHEASANT RUN
		CITY:			NEWTOWN
		STATE:			PA
		ZIP:			18940
		BUSINESS PHONE:		267-759-3681

	MAIL ADDRESS:	
		STREET 1:		375 PHEASANT RUN
		CITY:			NEWTOWN
		STATE:			PA
		ZIP:			18940

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ONCONOVA THERAPEUTICS, INC.
		DATE OF NAME CHANGE:	20090526

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ONCONOVA THERAPEUTICS INC
		DATE OF NAME CHANGE:	20001226

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Baxter Healthcare SA
		CENTRAL INDEX KEY:			0001582211
		STATE OF INCORPORATION:			V8
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36020
		FILM NUMBER:		15848285

	BUSINESS ADDRESS:	
		STREET 1:		THURGAUERSTRASSE 130
		CITY:			GLATTPARK (OPFIKON)
		STATE:			V8
		ZIP:			8152
		BUSINESS PHONE:		41 44 878 6000

	MAIL ADDRESS:	
		STREET 1:		THURGAUERSTRASSE 130
		CITY:			GLATTPARK (OPFIKON)
		STATE:			V8
		ZIP:			8152
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<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
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<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2015-05-06</periodOfReport>

    <notSubjectToSection16>1</notSubjectToSection16>

    <issuer>
        <issuerCik>0001130598</issuerCik>
        <issuerName>Onconova Therapeutics, Inc.</issuerName>
        <issuerTradingSymbol>ONTX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001582211</rptOwnerCik>
            <rptOwnerName>Baxter Healthcare SA</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>THURGAUERSTRASSE 130</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>GLATTPARK (OPFIKON)</rptOwnerCity>
            <rptOwnerState>V8</rptOwnerState>
            <rptOwnerZipCode>8152</rptOwnerZipCode>
            <rptOwnerStateDescription>SWITZERLAND</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2015-05-06</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>2603295</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">In preparation for the anticipated spin-off by Baxter International Inc. (&quot;Baxter&quot;) of Baxalta Incorporated (&quot;Baxalta&quot;), the reported securities were transferred from Baxter Healthcare SA, an indirectly wholly-owned subsidiary of Baxter to its affiliate Baxalta GmbH, which is also an indirect wholly-owned subsidiary of Baxter. In preparation for the anticipated spin-off, Baxter and Baxalta are engaging in a series of reorganization transactions, including the transfer of reported shares, which are anticipated to result in Baxalta GmbH becoming an indirect wholly-owned subsidiary of Baxalta.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ David P. Scharf, on behalf of Baxter Healthcare SA</signatureName>
        <signatureDate>2015-05-08</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</TEXT>
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<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>attachment1.htm
<DESCRIPTION>EX-24 DOCUMENT
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<PRE>
                            LIMITED POWER OF ATTORNEY

        Know all by these presents, that Baxter Healthcare SA, a company
organized and existing under the laws of Switzerland, having a principal place
of business at Thurgauerstrasse 130, Glattpark (Opfikon) 8152 Switzerland,
herewith grants power to David P. Scharf and Dawn M. Maloney, each to sign with
single signature on behalf of Baxter Healthcare SA, to:

        (1)     prepare, execute on behalf of Baxter Healthcare SA, and submit
        to the U.S. Securities and Exchange Commission (the "SEC") a Form ID,
        including amendments thereto, and any other documents necessary or
        appropriate to obtain codes and passwords enabling Baxter Healthcare SA
        to make electronic filings with the SEC of reports required by Section
        13 and Section 16(a) of the Securities Exchange Act of 1934 (the
        "Exchange Act") or any rule or regulation of the SEC;

        (2)     execute for and on behalf of Baxter Healthcare SA, in its
        capacity as a stockholder of any company registered with the SEC, any
        required (i) Schedules 13D and 13G in accordance with Section 13 of the
        Exchange Act and the rules thereunder, (ii) Forms 3, 4 and 5 in
        accordance with Section 16(a) of the Exchange Act and the rules
        thereunder, and (iii) Form 144 under Rule 144 of the Securities Act of
        1933;

        (3)     do and perform any and all acts for and on behalf of Baxter
        Healthcare SA which may be necessary or desirable to complete and
        execute any such Schedule 13D or 13G, Form 3, 4, 5, or 144 and complete
        and execute any amendment or amendments thereto, and timely file any
        such form with the SEC and any stock exchange or similar authority; and

        (4)     take any other action of any type whatsoever in connection with
        the foregoing which, in the opinion of such attorney-in-fact, may be of
        benefit to, in the best interest of, or legally required by, Baxter
        Healthcare SA, it being understood that the documents executed by such
        attorney-in-fact on behalf of Baxter Healthcare SA pursuant to this
        Power of Attorney shall be in such form and shall contain such terms and
        conditions as such attorney-in-fact may approve in such
        attorney-in-fact's discretion.

        Baxter Healthcare SA hereby grants to each such attorney-in-fact full
power and authority to do and perform any and every act and thing whatsoever
requisite, necessary, or proper to be done in the exercise of any of the rights
and powers herein granted, hereby ratifying and confirming all that such
attorney-in-fact shall lawfully do or cause or have caused to be done by virtue
of this power of attorney and the rights and powers herein granted. Baxter
Healthcare SA acknowledges that the foregoing attorneys-in-fact, in serving in
such capacity at the request of Baxter Healthcare SA, are not assuming any of
Baxter Healthcare SA's responsibilities to comply with Section 13 and 16 of the
Securities Exchange Act of 1934 and Rule 144 of the Securities Act of 1933.

        This Power of Attorney shall remain in full force and effect until the
earlier of (i) the date on which Baxter Healthcare SA is no longer required to
file Schedules 13D and 13G, and Forms 3, 4, 5 and 144 with respect to the
securities held by Baxter Healthcare SA, or (ii) December 31, 2015, in either
case unless earlier revoked by Baxter Healthcare SA.

Signed for and on behalf of Baxter Healthcare SA

By: /s/ Tony Fitzpatrick                By: /s/ Yvo Aebli
    ---------------------------------       -----------------------------------
Name: Tony Fitzpatrick                  Name: Yvo Aebli
Title: Vice President Operations EMEA   Title: Finance Director


</PRE>
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