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<SEC-DOCUMENT>0001075880-07-000061.txt : 20071030
<SEC-HEADER>0001075880-07-000061.hdr.sgml : 20071030
<ACCEPTANCE-DATETIME>20071030065616
ACCESSION NUMBER:		0001075880-07-000061
CONFORMED SUBMISSION TYPE:	6-K
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20071030
FILED AS OF DATE:		20071030
DATE AS OF CHANGE:		20071030

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NOVOGEN LTD
		CENTRAL INDEX KEY:			0001075880
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		FISCAL YEAR END:			0630

	FILING VALUES:
		FORM TYPE:		6-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-29962
		FILM NUMBER:		071197928

	BUSINESS ADDRESS:	
		STREET 1:		140 WICKS RD
		STREET 2:		NORTH RYDE
		CITY:			NEW SOUTH WALES 2113
		STATE:			C3
		ZIP:			2113
		BUSINESS PHONE:		01161298780088

	MAIL ADDRESS:	
		STREET 1:		107 NORTH RYDE
		CITY:			SYDNEY
		STATE:			C3
		ZIP:			1670
</SEC-HEADER>
<DOCUMENT>
<TYPE>6-K
<SEQUENCE>1
<FILENAME>form6k20071029.htm
<DESCRIPTION>FORM 6K 2007 10 29
<TEXT>
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      STATES</strong></font></div>
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      AND EXCHANGE COMMISSION</strong></font></div>
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      D.C. 20549</strong></font></div>
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      6-K</strong></font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 12pt; FONT-FAMILY: Times New Roman;"><strong>REPORT
      OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER
      THE</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 12pt; FONT-FAMILY: Times New Roman;"><strong>SECURITIES
      EXCHANGE ACT OF 1934</strong></font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">For
      the
      month of October, 2007</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Commission
      File Number <font style="DISPLAY: inline; FONT-FAMILY: Arial, sans-serif;">________________</font></font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 24pt; FONT-FAMILY: Times New Roman;"><strong>Novogen
      Limited</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">(Translation
      of registrant&#8217;s name into English)</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 18pt; FONT-FAMILY: Times New Roman;">140
      Wicks
      Road, North Ryde, NSW, Australia</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">(Address
      of principal executive office)</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">___________________________________</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Indicate
      by check mark whether the registrant files or will file annual reports under
      cover of Form 20-F or Form 40-F.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Form
      20-F
<font style="DISPLAY: inline;" face="Wingdings"><strong>x</strong></font><strong>&#160;</strong>Form
      40-F <font style="DISPLAY: inline;" face="Wingdings"><strong>o</strong></font></font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Indicate
      by check mark if the registrant is submitting the Form 6-K in paper as permitted
      by Regulation S-T Rule 101(b)(l):</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Note:
      Regulation S-T Rule 101 (b)( I) only permits the submission in paper of a Form
      6-K if submitted solely to provide an attached annual report to security
      holders.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Indicate
      by check mark if the registrant is submitting the Form 6-K in paper as permitted
      by Regulation S-T Rule lO1(b)(7):</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Note:
      Regulation S-T Rule l01(b)(7) only permits the submission in paper of a Form
      6-K
      if submitted to furnish a report or other document that the registrant foreign
      private issuer must furnish and make public under the laws of the jurisdiction
      in which the registrant is incorporated, domiciled or legally organized (the
      registrant&#8217;s &#8220;home country&#8221;), or under the rules of the home country exchange on
      which the registrant&#8217;s securities are traded, as long as the report or other
      document is not a press release, is not required to be and has not been
      distributed to the registrant&#8217;s security holders, and, if discussing a material
      event, has already been the subject of a Form 6-K submission or other Commission
      filing on EDGAR.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Indicate
      by check mark whether the registrant by furnishing the information contained
      in
      this Form is also thereby furnishing the information to the Commission pursuant
      to Rule l2g3-2(b) under the Securities Exchange Act of 1934. Yes <font style="DISPLAY: inline;" face="Wingdings"><strong>o</strong></font><strong>&#160;</strong>No
      <font style="DISPLAY: inline;" face="Wingdings"><strong>x</strong></font></font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">If
&#8220;Yes&#8221;
      is marked, indicate below the file number assigned to the registrant in
      connection with Rule 12g3-2(b):</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;"><strong>SIGNATURES</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;"><strong>Pursuant
      to the requirements of the Securities Exchange Act of 1934, the registrant
      has
      duly caused this report to be signed on its behalf </strong>by the undersigned,
      thereunto duly authorized.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;"><strong>Novogen
      Limited</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">(Registrant)</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;"><strong>/s/&#160;&#160;Ron
      Erratt</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Ronald
      Lea Erratt</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Company
      Secretary</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;"><strong>Date
      29 October, 2007</strong></font></div>
    <div><br></div><br>
    <div id="PGBRK" style="MARGIN-LEFT: 0pt; WIDTH: 100%; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt">
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        <div style="WIDTH: 100%; TEXT-ALIGN: center">
        </div>
        <div style="WIDTH: 100%; TEXT-ALIGN: center">
        </div>
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      <div id="HDR">
        <div id="GLHDR" style="WIDTH: 100%" align="right">
        </div>
      </div>
    </div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;"><strong>ASX
      &amp; MEDIA RELEASE</strong></font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;"><strong>29
      OCTOBER, 2007</strong></font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;"><strong>EUROPEAN
      SYMPOSIUM FOCUSES ON PHENOXODIOL AS AN INVESTIGATIONAL DRUG FOR OVARIAN CANCER
      MANAGEMENT</strong></font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Novogen
      Limited&#8217;s subsidiary, Marshall Edwards Inc. (NASDAQ: MSHL), has made the
      following announcement:</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;"><strong>Worldwide
      pivotal phase III study in women with recurrent ovarian cancer underway in
      USA,
      Europe and Australia</strong></font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">SYDNEY,
      AUSTRALIA; BERLIN and NEW CANAAN, CT--(Marketwire - October 29, 2007)
      -</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">A
      symposium on platinum resistant ovarian cancer held at the European Society
      for
      Gynecological Oncology in Berlin on Sunday, 28 October has confirmed the need
      for an effective chemosensitizing drug to support new platinum treatment
      regimens in resistant ovarian cancer.&#160; Leading cancer researchers speaking
      at the symposium described advances in platinum therapies and expressed
      enthusiasm for phenoxodiol as a promising new investigational drug as part
      of a
      new approach for this indication.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Phenoxodiol
      is being developed by the US oncology company Marshall Edwards, Inc. (NASDAQ:
      <u>MSHL</u>) as a novel therapeutic in combination with carboplatin for
      late-stage chemoresistant ovarian cancers, as well as a monotherapy for prostate
      and cervical cancers. &#160;Phenoxodiol is a novel-acting drug that inhibits key
      pro-survival signaling pathways operating within cancer cells causing selective
      cancer cell death and increased susceptibility to drugs like platinum and
      taxane, to which most ovarian cancer patients become resistant in late stage
      disease.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">The
      Berlin symposium was chaired by Professor Hani Gabra of the Ovarian Cancer
      Action Research Centre, Imperial College London, UK, and Professor Ignace
      Vergote, of the Catholic University of Leuven, Belgium. &#160;Medical
      professionals interested in viewing the archived symposium can watch it at
      <u>http://www.ovaturetrial.com/esgosymposium</u>.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Speaking
      at the symposium, Prof. Gabra said: "There are a number of interesting
      developments in platinum dosing schedules which may assist in improving tumour
      responses in resistant women, but the clinical efficacy of these will be
      enhanced by improved chemosensitization strategies."</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">"Already
      phenoxodiol has shown promise in improved platinum responses in Phase II
      studies. &#160;A major multinational Phase III study, the OVATURE Trial, is now
      underway in over 60 centers around the world, and we are excited to be part
      of
      this study," Prof. Gabra said.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">The
      <strong>OVA</strong>rian <strong>TU</strong>mor <strong>RE</strong>ponse
      (OVATURE) Trial is a major multi-center multinational Phase III clinical trial
      of phenoxodiol in women with advanced ovarian cancer resistant or refractory
      to
      platinum-based drugs, to determine its safety and effectiveness when used in
      combination with carboplatin.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Other
      speakers at the symposium included Professor Maria van der Burg
      (Erasmus&#160;University, Dijkzigt&#160;Hospital, Rotterdam, Netherlands),
      Professor David Bowtell (Peter MacCallum Cancer Centre, Melbourne, Australia)
      and Professor Alan Husband (Director of Research for Marshall Edwards,
      Inc.).</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Professor
      Bowtell reported on the functional significance of genes involved in platinum
      resistance, and Professor van der Burg presented new data on the benefits of
      weekly platinum dosing.&#160; A change from receiving platinum in the
      traditional dose pattern (every two to three weeks) to a weekly dosing regimen
      has been reported to provide a tumor response in some patients with recurrent
      ovarian cancer(1-3). &#160;This frequent dosing strategy has been incorporated
      into the Phase III OVATURE Trial. Thus, in addition to learning more about
      the
      safety and efficacy of phenoxodiol, researchers will learn more about the
      efficacy and safety of weekly carboplatin.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">The
      OVATURE Trial is recruiting ovarian cancer patients whose cancer initially
      responded to chemotherapy, but has since become resistant or refractory to
      traditional platinum treatments. The trial consists of two double blind
      treatment arms. &#160;Patients in one trial arm will receive weekly carboplatin
      and phenoxodiol. Patients in the other trial arm will also receive weekly
      carboplatin, but a placebo will be substituted for phenoxodiol. &#160;Neither
      patients nor their doctors will know to which trial arm the patients are
      randomized.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">The
      primary outcome of the trial is the assessment of the relative time it takes
      for
      the ovarian cancer to progress. An analysis of interim results will be possible
      after 95 patients have disease progression.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Patients
      will be recruited into 28 sites in the UK and Europe, 31 sites in the USA,
      and 4
      sites in Australia. The total number of patients to be enrolled in this pivotal
      study is 470.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">The
      trial
      design has been approved by the US Food and Drug Administration (FDA) as a
      Special Protocol Assessment (SPA), and provides for an interim analysis of
      the
      data, which if statistically significant can be used to support a request for
      marketing approval.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Professor
      Alan Husband said in his presentation at the symposium: "It is gratifying to
      hear from the research presented here today that there is new hope for those
      ovarian cancer patients who no longer respond to common chemotherapeutic
      drugs."</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">"We
      are
      keen to see whether the promising chemosensitizing effects seen in Phase II
      studies of phenoxodiol are reflected in the OVATURE trial when it is used in
      combination with a novel platinum therapeutic regimen," Professor Husband
      said.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">"The
      efficacy, coupled with the high safety and low side effect profile of
      phenoxodiol seen in previous studies, suggests that this new drug has the
      potential to offer improved therapeutic outcomes in ovarian cancer as well
      as
      other cancer targets, such as prostate and cervical cancers."</font></div>
    <div><br></div>
    <div id="PGBRK" style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt">
      <div id="FTR">
        <div id="GLFTR" style="WIDTH: 100%" align="left">&#160;</div>
      </div>
      <div id="PN" style="PAGE-BREAK-AFTER: always">
        <div style="WIDTH: 100%; TEXT-ALIGN: center">&#160;</div>
        <div style="WIDTH: 100%; TEXT-ALIGN: center">
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      <div id="HDR">
        <div id="GLHDR" style="WIDTH: 100%" align="right">&#160;</div>
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    </div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;"><strong>About
      phenoxodiol:</strong></font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Phenoxodiol
      is being developed as a chemosensitizing agent, in combination with platinum
      drugs for late stage, chemoresistant ovarian cancer and as a monotherapy for
      prostate and cervical cancers.&#160; It has a unique mechanism of action,
      binding to cancer cells via a surface oxidase, causing major downstream
      disturbances in expression of proteins necessary for their survival and
      responsible for the development of drug resistance.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Phenoxodiol
      appears to selectively inhibit the pro-survival regulator in cancer cells known
      as S-1-P (sphingosine-1-phosphate) that is over expressed in cancer cells.
      In
      response to phenoxodiol, the S-1-P content in cancer cells is decreased
      rendering those cells more sensitive to chemotherapy. Indeed, in laboratory
      studies, it has been demonstrated that cancer cells pre-treated with phenoxodiol
      were killed with lower doses of chemotherapy drugs.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Importantly,
      phenoxodiol has been shown not to adversely affect normal cells in animal and
      laboratory testing.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Phenoxodiol
      is being investigated as a therapy for late-stage, chemoresistant ovarian,
      prostate and cervical cancers. Phenoxodiol has received Fast Track status from
      the FDA to facilitate development as a therapy for recurrent ovarian and
      prostrate cancers.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Phenoxodiol
      is an investigational drug and, as such, is not commercially available. Under
      U.S. law, a new drug cannot be marketed until it has been investigated in
      clinical trials and approved by FDA as being safe and effective for the intended
      use.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Phenoxodiol
      is the first of a family of compounds in the Marshall Edwards, Inc.' drug
      pipeline of flavanoid derivatives.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;"><strong>About
      Marshall Edwards, Inc:</strong></font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Marshall
      Edwards, Inc. (NASDAQ: <u>MSHL</u>) is a specialist oncology company focused on
      the clinical development of novel anti-cancer therapeutics. &#160;These derive
      from a flavonoid technology platform, which has generated a number of novel
      compounds characterized by broad ranging activity against a range of cancer
      cell
      types with few side effects. &#160;The combination of anti-tumor cell activity
      and low toxicity is believed to be a result of the ability of these compounds
      to
      target an enzyme present on the surface of cancer cells, thereby inhibiting
      the
      production of pro-survival proteins within the cell. &#160;Marshall Edwards,
      Inc. has licensed rights from Novogen Limited (NASDAQ: <u>NVGN</u>) to bring
      three oncology drugs -- phenoxodiol, NV-196 and NV-143 -- to market globally.
      The Company's lead investigational drug, phenoxodiol, is in a Phase III
      multinational multi-centered clinical trial for patients with recurrent ovarian
      cancer. &#160;More information on the trial can be found at
<u>http://www.OVATUREtrial.com</u>.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">Marshall
      Edwards, Inc. is majority owned by Novogen, an Australian biotechnology company
      that is specializing in the development of therapeutics based on a flavonoid
      technology platform. Novogen, based in Sydney, Australia, is developing a range
      of therapeutics across the fields of oncology, cardiovascular disease and
      inflammatory diseases. More information on phenoxodiol and on the Novogen group
      of companies can be found at <u>www.marshalledwardsinc.com</u> and
<u>www.novogen.com</u>.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">References</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">(1)
      Piura
      B and Meirovitz M. Weekly single-agent carboplatin in heavily pretreated
      patients with recurrent ovarian, peritoneal and fallopian tube carcinoma. Eur
      J
      Gynaecol Oncol. 2005;26(4):386-90.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">(2)
      Van
      der Burg ME, van der Gaast A, Vergote I, Burger CW, van Doorn HC, de Wit R,
      Stoter G, Verweij J. What is the role of dose-dense therapy? Int J Gynecol
      Cancer. 2005 Nov-Dec;15 Suppl 3:233-240.</font></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;">(3)
      CaDron I, Leunen K, Amant F, Van Grop T, Neven P, Vergote I. The "Leuven" dose
      dense paclitaxel/carboplatin regimen in patients with recurrent ovarian cancer.
      Gynecol Oncol 2007, in press.</font></div>
    <div><br></div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman;"><em>Under
      U.S. law, a new drug cannot be marketed until it has been investigated in
      clinical trials and approved by the FDA as being safe and effective for the
      intended use. Statements included in this press release that are not historical
      in nature are "forward-looking statements" within the meaning of the "safe
      harbor" provisions of the Private Securities Litigation Reform Act of 1995.
      You
      should be aware that our actual results could differ materially from those
      contained in the forward-looking statements, which are based on management's
      current expectations and are subject to a number of risks and uncertainties,
      including, but not limited to, our failure to successfully commercialize our
      product candidates; costs and delays in the development and/or FDA approval,
      or
      the failure to obtain such approval, of our product candidates; uncertainties
      in
      clinical trial results; our inability to maintain or enter into, and the risks
      resulting from our dependence upon, collaboration or contractual arrangements
      necessary for the development, manufacture, commercialization, marketing, sales
      and distribution of any products; competitive factors; our inability to protect
      our patents or proprietary rights and obtain necessary rights to third party
      patents and intellectual property to operate our business; our inability to
      operate our business without infringing the patents and proprietary rights
      of
      others; general economic conditions; the failure of any products to gain market
      acceptance; our inability to obtain any additional required financing;
      technological changes; government regulation; changes in industry practice;
      and
      one-time events. We do not intend to update any of these factors or to publicly
      announce the results of any revisions to these forward looking
      statement.&#160;</em></font></div>
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