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Commitments and Contingencies - Additional Information (Details) |  |  |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | --- | --- | ---
Aug. 04, 2025 ft² | Mar. 10, 2025 ft² | Aug. 07, 2020 USD ($) ft² | Jun. 30, 2024 USD ($) | Aug. 31, 2022 ft² | Jun. 30, 2021 ft² | Dec. 31, 2025 USD ($) | Dec. 31, 2024 USD ($)
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |
Operating lease right-of-use assets |  |  |  |  |  |  | $ 19,230,000 | $ 21,756,000
Operating lease liabilities |  |  |  |  |  |  | 22,958,000 |
Sublease income |  |  |  |  |  |  | $ 1,838,000 |
Weighted-average remaining lease term |  |  |  |  |  |  | 5 years 4 months 24 days | 6 years 4 months 24 days
Weighted-average discount rate |  |  |  |  |  |  | 11.90% | 11.90%
Restricted cash, non-current |  |  |  |  |  |  | $ 1,538,000 | $ 981,000
Asset impairment related to operating lease right-of-use assets |  |  |  | $ 0 |  |  |  |
Chesapeake Master Lease |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |
Operating lease, area of property available | ft² |  |  | 71,646 |  |  |  |  |
Operating lease, area of property, extension space available | ft² |  |  | 25,956 |  |  |  |  |
Operating lease, area of property, additional space available | ft² |  |  | 45,690 |  |  |  |  |
Operating lease, initial term of contract |  |  | 10 years |  |  |  |  |
Operating lease, option to extend |  |  | true |  |  |  |  |
Operating lease, extended additional term |  |  | 8 years |  |  |  |  |
Tenant improvement allowance |  |  | $ 4,800,000 |  |  |  |  |
Operating lease, area of property subleased | ft² |  |  | 10,000 |  |  |  |  |
Operating lease, area of property, additional space remaining | ft² |  |  |  |  |  | 35,690 |  |
Sublease, area of property leased | ft² | 11,975 | 11,773 |  |  | 11,655 |  |  |
Sublease term expires |  | 36 months |  |  |  |  |  |
Sublease agreement minimum period to provide written notice period to other party |  | 9 months |  |  |  |  |  |
Right to terminate sublease prior to expiration date minimum period |  | 24 months |  |  |  |  | 15 months |
Sublease, area of property expected to be leased | ft² |  |  |  |  |  | 10,500 |  |
Increase decrease in operating lease sublease area of property leased | ft² |  |  |  |  | 13,743 |  |  |
Operating sublease, option to extend, description |  | The sublessee has a one-time right to terminate the sublease agreement no earlier than twenty-four months after the commencement date by providing at least nine months written notice to the other party. The subtenant is responsible for certain operating expenses and taxes throughout the term under the sublease agreement. |  |  |  |  | The sublease has an early termination option under which both the Company and the sublessee have the right to terminate the sublease prior to the expiration date by providing at least fifteen months written notice to the other party. The subtenant does not have an option to extend the sublease term. Rent for this sublease is subject to scheduled annual increases and the subtenant is responsible for certain operating expenses and taxes throughout the term under the sublease agreement. |
Operating sublease, option to extend |  |  |  |  | false |  |  |
Sublease income |  |  |  |  |  |  | $ 1,400,000 | $ 800,000
Weighted-average discount rate |  |  |  |  |  |  |  | 8.00%
Restricted cash, non-current |  |  |  |  |  |  | 1,500,000 | $ 1,600,000
Asset impairment related to operating lease right-of-use assets |  |  |  |  |  |  |  | $ 1,500,000
Stanford Agreement |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |
Additional milestone payment |  |  |  |  |  |  | 200,000 |
Royalty payments |  |  |  |  |  |  | 0 |
Stanford Agreement | Maximum |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |
Aggregate millstone payments |  |  |  |  |  |  | $ 400,000 |

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