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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2025
Income Tax Disclosure [Abstract] |
Summary of Income (Loss) Before Provision for Income Taxes | For financial reporting purposes, income (loss) before provision for income taxes, includes the following components (in thousands):
|  | Years Ended December 31, |
|  | 2025 |  |  | 2024 |
Domestic |  | $ | (31,885 | ) |  | $ | (63,118 | )
Foreign |  |  | (1,491 | ) |  |  | — |
Loss before income taxes |  | $ | (33,376 | ) |  | $ | (63,118 | )
Summary of Reconciliation of Effective Tax Rate and Federal Statutory Tax Rate | A reconciliation of the Company’s effective tax rate and federal statutory tax rate is summarized as follows (in thousands):
|  | Years Ended December 31, |
|  | 2025 |  |  | 2024 |
Federal income tax provision at statutory rate |  | $ | (7,009 | ) |  |  | 21.0 | % |  | $ | (13,255 | ) |  |  | 21.0 | %
Foreign tax effects |  |  | (161 | ) |  |  | 0.5 | % |  |  | — |  |  |  | — | %
Tax credits: |  |  |  |  |  |  |  |  |  |  |  |
Research and development |  |  | (513 | ) |  |  | 1.5 | % |  |  | (1,439 | ) |  |  | 2.3 | %
Change in valuation allowance |  |  | 6,571 |  |  |  | (19.7 | %) |  |  | 12,832 |  |  |  | (20.3 | %)
Nontaxable or nondeductible items: |  |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation |  |  | 620 |  |  |  | (1.9 | %) |  |  | 1,830 |  |  |  | (2.9 | %)
Other |  |  | 492 |  |  |  | (1.4 | %) |  |  | 32 |  |  |  | (0.1 | %)
Effective income tax rate |  | $ | — |  |  |  | — | % |  | $ | — |  |  |  | — | %
Summary of Significant Components of Deferred Tax Assets and Liabilities for Federal and State Income Taxes | Significant components of our deferred tax assets for federal and state income taxes are as follows (in thousands):
|  | December 31, |
|  | 2025 |  |  | 2024 |
Deferred tax assets: |  |  |  |  |  |
Net operating loss carryforward |  | $ | 66,024 |  |  | $ | 53,485 |
Research tax credits |  |  | 12,169 |  |  |  | 11,353 |
Capitalized research and development expenses |  |  | 21,547 |  |  |  | 27,436 |
Lease liability |  |  | 6,605 |  |  |  | 7,137 |
Stock-based compensation |  |  | 2,243 |  |  |  | 2,256 |
Reserves and accruals |  |  | 551 |  |  |  | 1,585 |
Intangible assets |  |  | 110 |  |  |  | 127 |
Total deferred tax assets |  |  | 109,249 |  |  |  | 103,379 |
Less valuation allowance |  |  | (103,593 | ) |  |  | (96,870 | )
Net deferred tax assets |  |  | 5,656 |  |  |  | 6,509 |
Deferred tax liabilities: |  |  |  |  |  |
Right-of-use assets |  |  | (5,532 | ) |  |  | (6,159 | )
Property and equipment |  |  | (73 | ) |  |  | (311 | )
Prepaid assets |  |  | (51 | ) |  |  | (39 | )
Total deferred tax liabilities |  |  | (5,656 | ) |  |  | (6,509 | )
Net deferred tax assets |  | $ | — |  |  | $ | — |
Schedule of Reconciliation of Change in Valuation Allowance | The following table presents a reconciliation of the total change in the valuation allowance (in thousands):
|  | Years Ended December 31, |
|  | 2025 |  |  | 2024 |
Balance at beginning of period |  | $ | 96,870 |  |  | $ | 83,680 |
Change charged to income tax expense |  |  | 6,723 |  |  |  | 13,190 |
Balance at end of period |  | $ | 103,593 |  |  | $ | 96,870 |
Summary of Gross Unrecognized Tax Benefits | The following table summarizes the activity in the Company’s gross unrecognized tax benefits (in thousands):
|  | Years Ended December 31, |
|  | 2025 |  |  | 2024 |
Balance at beginning of period |  | $ | 23,832 |  |  | $ | 18,748 |
Decrease related to prior year positions |  |  | — |  |  |  | — |
Increase related to current year positions |  |  | 2,943 |  |  |  | 5,084 |
Balance at end of period |  | $ | 26,775 |  |  | $ | 23,832 |

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