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Segment Reporting | 12 Months Ended
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Dec. 31, 2025
Segment Reporting [Abstract] |
Segment Reporting | 12. Segment Reporting Operating segments are defined as components of an entity for which separate financial information is available and that is regularly reviewed by the chief operating decision maker (CODM), in deciding how to allocate resources to an individual segment and in assessing performance. The Company’s CODM is its chief executive officer. Based on the information used by the CODM to allocate resources, the Company has determined it operates in one segment. The Company’s operating segment generates revenue from its collaboration agreements as described in Note 5. The CODM assesses performance for the Company’s operating segment and decides how to allocate resources based on the Company’s cash runway and Net Loss that also is reported on the Consolidated Statements of Operations and Comprehensive Loss Income as Net Loss. Net loss is used to monitor budget versus actual results. The measure of segment assets is reported on the balance sheets as total assets. As of December 31, 2025 and 2024, all of the Company’s property and equipment was maintained in the United States. For the year ended December 31, 2025 and 2024, all of the Company’s revenue was generated and incurred in the United States. Please refer to the consolidated financial statements for further information related to these measures of segment performance. In addition, research and development and general and administrative expenses are significant segment expenses regularly provided to the CODM with the following categories:
|  | Years Ended December 31, |
|  | 2025 |  |  | 2024 |
|  | (In thousands) |
Significant Segment Expenses: |  |  |  |  |  |
Personnel related costs |  | $ | 13,544 |  |  | $ | 23,936 |
Research and development expenses |  |  | 6,795 |  |  |  | 14,346 |
Clinical trial expenses |  |  | 4,325 |  |  |  | 11,285 |
General and administrative expenses |  |  | 7,062 |  |  |  | 8,952 |
Facilities expenses |  |  | 6,529 |  |  |  | 7,734 |
Stock-based compensation expense |  |  | 2,782 |  |  |  | 7,407 |
Depreciation and other segment expenses (Note A) |  |  | 1,291 |  |  |  | 2,266 |
Total segment expenses |  |  | 42,328 |  |  |  | 75,926 |
Restructuring charges |  |  | 1,480 |  |  |  | 3,343 |
Impairment charges |  |  | — |  |  |  | 1,469 |
Total segment and operating expenses |  |  | 43,808 |  |  |  | 80,738 |
(Note A) Other segment expense include depreciation expense and other miscellaneous expenses.

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- Definition The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 21 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-21 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name 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