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Stock-Based Compensation (Tables) | 12 Months Ended
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Dec. 31, 2025
Share-Based Payment Arrangement [Abstract] |
Summary of Stock Option Activity | The following table summarizes the stock option activity during the year ended December 31, 2025:
|  | Options Outstanding |  |  | Weighted-average Exercise Price |  |  | Weighted-average Remaining Contractual Term (in years) |  |  | Weighted-average Grant Date Fair Value |  |  | Aggregate Intrinsic Value (in thousands) |
Outstanding at December 31, 2024 |  |  | 571,308 |  |  | $ | 50.09 |  |  |  | 5.7 |  |  |  |  |  | $ | — |
Granted |  |  | 130,963 |  |  | $ | 6.95 |  |  |  |  |  | $ | 5.14 |  |  |  |
Exercised |  |  | — |  |  |  |  |  |  |  |  |  |  |  |  |
Canceled/forfeited |  |  | (242,496 | ) |  | $ | 36.84 |  |  |  |  |  |  |  |  |  |
Outstanding at December 31, 2025 |  |  | 459,775 |  |  | $ | 6.93 |  |  |  | 6.1 |  |  |  |  |  | $ | 12 |
Exercisable at December 31, 2025 |  |  | 354,334 |  |  | $ | 7.37 |  |  |  | 5.2 |  |  |  |  |  | $ | 9 |
Vested or expected to vest at December 31, 2025 |  |  | 459,775 |  |  | $ | 6.93 |  |  |  | 6.1 |  |  |  |  |  | $ | 12 |
Summary of Fair Value of Option Grant Estimated Using Black-Scholes Option-Pricing Model | The fair value of each option grant was estimated on the date of grant using the Black-Scholes option-pricing model with the following assumptions:
| Years Ended December 31,
| 2025 |  |  | 2024
Expected volatility |  | 87-91 |  | % | 98-105 |  | %
Risk-free interest rate |  | 3.8-4.2 |  | % | 3.7-4.7 |  | %
Expected option life (in years) |  | 5.2-6.1 |  |  | 5.2-6.1 |  |
Expected dividend yield |  |  | — |  | % |  | — |  | %
Fair value per share of common stock |  | $5.44 - $9.76 |  |  | $11.22-$25.40 |  |
Summary of Components of Stock-Based Compensation Expense Recognized | The following table summarizes the components of stock-based compensation expense recognized in the Company’s statement of operations and comprehensive loss (in thousands):
|  | Years Ended December 31, |
|  | 2025 |  |  | 2024 |
Research and development |  | $ | 1,162 |  |  | $ | 3,152 |
General and administrative |  |  | 1,620 |  |  |  | 4,255 |
Total |  | $ | 2,782 |  |  | $ | 7,407 |
Summary of Restricted Stock Awards Activity | The following table summarizes the activity of the restricted stock units during the year ended December 31, 2025:
|  | RSU Outstanding |  |  | Weighted-average Grant Date Fair Value |
Outstanding at December 31, 2024 |  |  | — |  |  | $ | — |
Granted |  |  | 249,500 |  |  | $ | 5.61 |
Vested |  |  | — |  |  | $ | — |
Canceled/forfeited |  |  | — |  |  | $ | — |
Outstanding at December 31, 2025 |  |  | 249,500 |  |  | $ | 5.61 |

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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Disclosure of the number and weighted-average grant date fair value for restricted stock and restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock and restricted stock units that were granted, vested, or forfeited during the year. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(2) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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