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Commitments and Contingencies - Additional Information (Details)
 1 Months Ended 12 Months Ended
Aug. 04, 2025
ft²
Mar. 10, 2025
ft²
Aug. 07, 2020
USD ($)
ft²
Jun. 30, 2024
USD ($)
Aug. 31, 2022
ft²
Jun. 30, 2021
ft²
Dec. 31, 2025
USD ($)
Dec. 31, 2024
USD ($)
Commitments And Contingencies [Line Items]                
Operating lease right-of-use assets             $ 19,230,000 $ 21,756,000
Operating lease liabilities             22,958,000  
Sublease income             $ 1,838,000  
Weighted-average remaining lease term             5 years 4 months 24 days 6 years 4 months 24 days
Weighted-average discount rate             11.90% 11.90%
Restricted cash, non-current             $ 1,538,000 $ 981,000
Asset impairment related to operating lease right-of-use assets       $ 0        
Chesapeake Master Lease                
Commitments And Contingencies [Line Items]                
Operating lease, area of property available | ft²     71,646          
Operating lease, area of property, extension space available | ft²     25,956          
Operating lease, area of property, additional space available | ft²     45,690          
Operating lease, initial term of contract     10 years          
Operating lease, option to extend     true          
Operating lease, extended additional term     8 years          
Tenant improvement allowance     $ 4,800,000          
Operating lease, area of property subleased | ft²     10,000          
Operating lease, area of property, additional space remaining | ft²           35,690    
Sublease, area of property leased | ft² 11,975 11,773     11,655      
Sublease term expires   36 months            
Sublease agreement minimum period to provide written notice period to other party   9 months            
Right to terminate sublease prior to expiration date minimum period   24 months         15 months  
Sublease, area of property expected to be leased | ft²           10,500    
Increase decrease in operating lease sublease area of property leased | ft²         13,743      
Operating sublease, option to extend, description   The sublessee has a one-time right to terminate the sublease agreement no earlier than twenty-four months after the commencement date by providing at least nine months written notice to the other party. The subtenant is responsible for certain operating expenses and taxes throughout the term under the sublease agreement.         The sublease has an early termination option under which both the Company and the sublessee have the right to terminate the sublease prior to the expiration date by providing at least fifteen months written notice to the other party. The subtenant does not have an option to extend the sublease term. Rent for this sublease is subject to scheduled annual increases and the subtenant is responsible for certain operating expenses and taxes throughout the term under the sublease agreement.  
Operating sublease, option to extend         false      
Sublease income             $ 1,400,000 $ 800,000
Weighted-average discount rate               8.00%
Restricted cash, non-current             1,500,000 $ 1,600,000
Asset impairment related to operating lease right-of-use assets               $ 1,500,000
Stanford Agreement                
Commitments And Contingencies [Line Items]                
Additional milestone payment             200,000  
Royalty payments             0  
Stanford Agreement | Maximum                
Commitments And Contingencies [Line Items]                
Aggregate millstone payments             $ 400,000