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Stockholders' Equity (Tables) | 9 Months Ended
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Sep. 30, 2019
Equity [Abstract] |
Schedule of the allocation of stock-based compensation | The stock-based compensation expense was allocated as follows:
| Three months ended September 30, | Nine months ended September 30,
| 2019 |  | 2018 | 2019 |  | 2018
Cost of product sales | $ | 32 |  |  | $ | 35 |  | $ | 124 |  |  | $ | 132 |
Research and development cost | 34 |  |  | 26 |  | 168 |  |  | 215 |
General and administrative expense | 835 |  |  | 300 |  | 2,607 |  |  | 506 |
Total | $ | 901 |  |  | $ | 361 |  | $ | 2,899 |  |  | $ | 853 |
Schedule of assumptions used in the Black-Scholes-Merton option-pricing model | The following assumptions were used in the Black-Scholes-Merton pricing model to estimate the fair value of options granted during the periods presented:
| Three months ended September 30, | Nine months ended September 30,
| 2019 |  | 2018 | 2019 |  | 2018
Expected stock volatility | 86.2% - 86.5% |  |  | 78.0% - 79.3% |  | 82.3% - 87.5% |  |  | 78.0% - 86.3% |
Risk free interest rate | 1.7% - 1.8% |  |  | 2.6% - 2.9% |  | 1.7% - 2.6% |  |  | 2.1% - 2.9% |
Expected years until exercise | 3.5 |  |  | 3.5 |  | 1.0 - 4.0 |  |  | 2.5 - 3.5 |
Dividend yield | 0 | % |  | 0 | % | 0 | % |  | 0 | %

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- Definition Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -URI http://asc.fasb.org/extlink&oid=115993241&loc=d3e301413-122809 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5047-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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