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Note 9 - Stockholders' Equity (Tables)
3 Months Ended
Mar. 31, 2021
Notes Tables  
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
  

Three Months Ended March 31,

 
  

2021

  

2020

 

Cost of product sales

 $31  $22 

Research and development cost

  42   105 

General and administrative expense

  606   829 

Total

 $679  $956