Exhibit 32.1

Certification of Principal Executive Officer Pursuant to Section 906 of the Sarbanes-Oxley Act

I, Fredi Nisan, the Principal Executive Officer of RYVYL Inc. (the “Company”), hereby certify that, pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, 18 U.S.C. Section 1350, to my knowledge:

| 1. | The Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2024 (the “Form 10-K”) fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

| 2. | The information contained in the Form 10-K fairly presents, in all material respects, the financial condition and results of operations of the Company.

| By: | /s/ Fredi Nisan
| Name: | Fredi Nisan
| Title: | Chief Executive Officer
|  | (Principal Executive Officer)

Date: March 28, 2025