<SEC-DOCUMENT>0000929638-21-000299.txt : 20210212
<SEC-HEADER>0000929638-21-000299.hdr.sgml : 20210212
<ACCEPTANCE-DATETIME>20210212160137
ACCESSION NUMBER:		0000929638-21-000299
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20210212
DATE AS OF CHANGE:		20210212

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ESSA Pharma Inc.
		CENTRAL INDEX KEY:			0001633932
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			A1
		FISCAL YEAR END:			0930

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-88939
		FILM NUMBER:		21627018

	BUSINESS ADDRESS:	
		STREET 1:		SUITE 720
		STREET 2:		999 WEST BROADWAY
		CITY:			VANCOUVER
		STATE:			A1
		ZIP:			V5Z 1K5
		BUSINESS PHONE:		(778) 331-0962

	MAIL ADDRESS:	
		STREET 1:		SUITE 720
		STREET 2:		999 WEST BROADWAY
		CITY:			VANCOUVER
		STATE:			A1
		ZIP:			V5Z 1K5

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Soleus Capital, LLC
		CENTRAL INDEX KEY:			0001786724
		IRS NUMBER:				364882601
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		104 FIELD POINT ROAD
		STREET 2:		FLOOR 2
		CITY:			GREENWICH
		STATE:			CT
		ZIP:			06830
		BUSINESS PHONE:		203-542-5527

	MAIL ADDRESS:	
		STREET 1:		104 FIELD POINT ROAD
		STREET 2:		FLOOR 2
		CITY:			GREENWICH
		STATE:			CT
		ZIP:			06830
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>schedule13ga.htm
<DESCRIPTION>AMENDMENT NO. 3
<TEXT>
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              <div style="font-family: 'Times New Roman';"><font style="font-weight: bold;">CUSIP No. </font>29668H104</div>
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              <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">13G/A</div>
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            <td style="width: 33%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">&#160;</td>
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    <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">SECURITIES AND EXCHANGE COMMISSION<br>
      Washington, D.C. 20549</div>
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    <div style="text-align: center; font-size: 18pt; font-weight: bold;">SCHEDULE 13G/A</div>
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    <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">Under the Securities Exchange Act of 1934</div>
    <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;"> <br>
    </div>
    <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">(Amendment No.&#160;3)*</div>
    <div>&#160;</div>
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              <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">ESSA Pharma Inc.</div>
            </div>
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          <td style="width: 100%; vertical-align: top;">
            <div style="text-align: center; font-family: 'Times New Roman'; font-size: 8pt;">(Name of Issuer)</div>
            <div style="text-align: center; font-family: 'Times New Roman'; font-size: 8pt;"> <br>
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              <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">Common Shares</div>
            </div>
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            <div style="text-align: center; font-family: 'Times New Roman'; font-size: 8pt;">(Title of Class of Securities)</div>
            <div style="text-align: center; font-family: 'Times New Roman'; font-size: 8pt;"> <br>
            </div>
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              <div style="text-align: center; font-family: 'Times New Roman';">29668H104</div>
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            <div style="text-align: center; font-family: 'Times New Roman'; font-size: 8pt;">(CUSIP Number)</div>
            <div style="text-align: center; font-family: 'Times New Roman'; font-size: 8pt;"> <br>
            </div>
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            <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">December 31, 2020</div>
          </td>
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          <td style="width: 100%; vertical-align: top;">
            <div style="text-align: center; font-family: 'Times New Roman'; font-size: 8pt;">(Date of Event Which Requires Filing of this Statement)</div>
          </td>
        </tr>

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    <div style="font-family: 'Times New Roman';">Check the appropriate box to designate the rule pursuant to which this Schedule is filed:</div>
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            <div style="font-family: 'Times New Roman';">&#9744;</div>
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            <div style="font-family: 'Times New Roman';">Rule 13d-1(b)</div>
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            <div style="font-family: 'Times New Roman';">&#9745;</div>
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            <div style="font-family: 'Times New Roman';">Rule 13d-1(c)</div>
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            <div style="font-family: 'Times New Roman';">&#9744;</div>
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            <div style="font-family: 'Times New Roman';">Rule 13d-1(d)</div>
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    <div style="text-align: justify; font-family: 'Times New Roman';">*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent
      amendment containing information which would alter the disclosures provided in a prior cover page.</div>
    <div><br>
    </div>
    <div style="text-align: justify; font-family: 'Times New Roman';">The information required in the remainder of this cover page shall not be deemed to be &#8220;filed&#8221; for the purpose of Section 18 of the Securities Exchange Act of 1934 (&#8220;Act&#8221;) or otherwise
      subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes in the Form of Schedule 13G).</div>
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              <div style="font-family: 'Times New Roman';"><font style="font-weight: bold;">CUSIP No. </font>29668H104</div>
            </td>
            <td style="width: 34%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">13G/A</div>
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            <td style="width: 33%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">&#160;</td>
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            <div style="text-align: center; font-family: 'Times New Roman';">1</div>
          </td>
          <td colspan="4" style="width: 90.68%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman'; font-size: 8pt; font-weight: bold;">NAME OF REPORTING PERSON</div>
            <div><font style="font-size: 8pt; font-family: 'Times New Roman'; font-weight: bold;">IRS IDENTIFICATION NO. OF ABOVE PERSON (ENTITIES ONLY)<br>
              </font>&#160;</div>
          </td>
        </tr>
        <tr>
          <td colspan="4" style="width: 90.68%; vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman';">Soleus Capital, LLC</div>
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td rowspan="3" style="width: 9.15%; vertical-align: middle; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman';">2</div>
          </td>
          <td colspan="4" style="width: 90.68%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman'; font-size: 8pt; font-weight: bold;">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*</div>
          </td>
        </tr>
        <tr>
          <td colspan="3" rowspan="2" style="width: 26.29%; vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 64.39%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); text-align: right;">
            <div style="font-family: 'Times New Roman';">(a) &#9744;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </div>
          </td>
        </tr>
        <tr>
          <td style="width: 64.39%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0); text-align: right;">
            <div style="font-family: 'Times New Roman';">(b) &#9744;&#160;&#160;&#160;&#160;&#160;&#160;&#160; </div>
          </td>
        </tr>
        <tr>
          <td rowspan="2" style="width: 9.15%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman';">3</div>
          </td>
          <td colspan="4" style="width: 90.68%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman'; font-size: 8pt; font-weight: bold;">SEC USE ONLY</div>
          </td>
        </tr>
        <tr>
          <td colspan="4" style="width: 90.68%; vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
            <div>&#160;</div>
            <div> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td rowspan="2" style="width: 9.15%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman';">4</div>
          </td>
          <td colspan="4" style="width: 90.68%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman'; font-size: 8pt; font-weight: bold;">CITIZENSHIP OR PLACE OF ORGANIZATION</div>
          </td>
        </tr>
        <tr>
          <td colspan="4" style="width: 90.68%; vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
            <div style="font-family: 'Times New Roman';">Delaware, U.S.A.</div>
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td colspan="2" rowspan="8" style="width: 20.13%; vertical-align: middle; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman'; font-size: 8pt; font-weight: bold;">NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH</div>
          </td>
          <td rowspan="2" style="width: 8.99%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman';">5</div>
          </td>
          <td colspan="2" style="width: 70.55%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman'; font-size: 8pt; font-weight: bold;">SOLE VOTING POWER</div>
          </td>
        </tr>
        <tr>
          <td colspan="2" style="width: 70.55%; vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
            <div style="font-family: 'Times New Roman';">3,474,658</div>
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td rowspan="2" style="width: 8.99%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman';">6</div>
          </td>
          <td colspan="2" style="width: 70.55%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman'; font-size: 8pt; font-weight: bold;">SHARED VOTING POWER</div>
          </td>
        </tr>
        <tr>
          <td colspan="2" style="width: 70.55%; vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
            <div>&#160;</div>
            <div> <br>
            </div>
            <div> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td rowspan="2" style="width: 8.99%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman';">7</div>
          </td>
          <td colspan="2" style="width: 70.55%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman'; font-size: 8pt; font-weight: bold;">SOLE DISPOSITIVE POWER</div>
          </td>
        </tr>
        <tr>
          <td colspan="2" style="width: 70.55%; vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
            <div style="font-family: 'Times New Roman';">3,474,658</div>
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td rowspan="2" style="width: 8.99%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman';">8</div>
          </td>
          <td colspan="2" style="width: 70.55%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman'; font-size: 8pt; font-weight: bold;">SHARED DISPOSITIVE POWER</div>
          </td>
        </tr>
        <tr>
          <td colspan="2" style="width: 70.55%; vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
            <div>&#160;</div>
            <div> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td rowspan="2" style="width: 9.15%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman';">9</div>
          </td>
          <td colspan="4" style="width: 90.68%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman'; font-size: 8pt; font-weight: bold;">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</div>
          </td>
        </tr>
        <tr>
          <td colspan="4" style="width: 90.68%; vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
            <div style="font-family: 'Times New Roman';">3,474,658</div>
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td style="width: 9.15%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman';">10</div>
          </td>
          <td colspan="4" style="width: 90.68%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman'; font-size: 8pt; font-weight: bold;">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW&#160; (9) EXCLUDES CERTAIN SHARES*<font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" id="TRGRRTFtoHTMLTab">&#160;</font>&#160;&#160;&#160;&#160;&#160;&#160; &#9744;</div>
            <div>&#160;</div>
            <div> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td rowspan="2" style="width: 9.15%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman';">11</div>
          </td>
          <td colspan="4" style="width: 90.68%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman'; font-size: 8pt; font-weight: bold;">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)</div>
          </td>
        </tr>
        <tr>
          <td colspan="4" style="width: 90.68%; vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
            <div style="font-family: 'Times New Roman';">9.99%<font style="font-weight: bold;"> (1)</font></div>
            <div style="font-family: 'Times New Roman';"><font style="font-weight: bold;"> <br>
              </font></div>
          </td>
        </tr>
        <tr>
          <td rowspan="2" style="width: 9.15%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman';">12</div>
          </td>
          <td colspan="4" style="width: 90.68%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman'; font-size: 8pt; font-weight: bold;">TYPE OF REPORTING PERSON*</div>
          </td>
        </tr>
        <tr>
          <td colspan="4" style="width: 90.68%; vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
            <div style="font-family: 'Times New Roman';">OO</div>
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
          </td>
        </tr>

    </table>
    <div><font style="font-family: 'Times New Roman';">(1)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" id="TRGRRTFtoHTMLTab">&#160;</font><font style="font-family: 'Times New Roman';">Based on a total of 33,682,383
        Common Shares outstanding as of January 13, 2021 as provided by ESSA Pharma, Inc. (the &#8220;Issuer&#8221;).</font></div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
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        <hr style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;" noshade="noshade"></div>
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    <div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" border="0" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 33.34%; vertical-align: top; border-left: #000000 1px solid; border-right: #000000 1px solid; border-top: #000000 1px solid; border-bottom: #000000 1px solid;">
              <div style="font-family: 'Times New Roman';"><font style="font-weight: bold;">CUSIP No. </font>29668H104</div>
            </td>
            <td style="width: 34%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">13G/A</div>
            </td>
            <td style="width: 33%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">&#160;</td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z6602f161d2574b0fbba6959787150512" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Item 1(a)</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Name of Issuer:</div>
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        </tr>

    </table>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z38ec7d9bb2744e4fbd874d17d4987cc8" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">ESSA Pharma, Inc.</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zc83f1bf7dba84953a617d047bc16b24c" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Item 1(b)</td>
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            <div style="font-family: 'Times New Roman'; font-weight: bold;">Address of Issuer&#8217;s Principal Executive Offices:</div>
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    </table>
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        <tr>
          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Suite 720, 999 West Broadway</div>
          </td>
        </tr>

    </table>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="za1acde5023b449fb840e050a0f0a4904" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Vancouver, British Columbia, Canada, V5Z 1K5</div>
          </td>
        </tr>

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    <div><br>
    </div>
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        <tr>
          <td style="width: 72pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Item 2(a)</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Name of Person Filing:</div>
          </td>
        </tr>

    </table>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zb81c83df7adc4173a3599e81bddfa102" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">The Reporting Person is Soleus Capital, LLC. Additionally, information is included herein with respect to (i)&#160;Soleus Capital Master Fund, L.P., a Cayman Islands exempted limited partnership (&#8220;Soleus
              Master Fund&#8221;); (ii)&#160;Soleus Capital Special Opportunities Fund, L.P., a Delaware limited partnership (&#8220;Soleus Special Fund&#8221;), and (iii)&#160;Soleus Capital Group, LLC, a Delaware limited liability company (&#8220;Soleus Group&#8221;).&#160; The Reporting Person is
              the sole general partner of each of Soleus Master Fund and Soleus Special Fund, and Soleus Group is the sole managing member of the Reporting Person.&#160; Mr. Guy Levy is the sole managing member of Soleus Group and hereby disclaims beneficial
              ownership of shares held by any of the entities named herein.</div>
          </td>
        </tr>

    </table>
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    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z25281e36dfb0411e95366fe790c22e44" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Item 2(b)</td>
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            <div style="font-family: 'Times New Roman'; font-weight: bold;">Address of Principal Business Office or, if None, Residence:</div>
          </td>
        </tr>

    </table>
    <div> <br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zb5e35359b2a14d5eb2d892a8c12aac66" cellpadding="0" cellspacing="0">

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          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">104 Field Point Road, 2nd Floor</div>
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        </tr>

    </table>
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          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
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            <div style="font-family: 'Times New Roman';">Greenwich, CT 06830</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z5cb698df4bc44ba5ae5b3a99bee9a125" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Item 2(c)</td>
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          </td>
        </tr>

    </table>
    <div> <br>
    </div>
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            <div style="font-family: 'Times New Roman';">Delaware, U.S.A.</div>
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        </tr>

    </table>
    <div><br>
    </div>
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          <td style="width: 72pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Item 2(d)</td>
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            <div style="font-family: 'Times New Roman'; font-weight: bold;">Title of Class of Securities:</div>
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    </table>
    <div> <br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zd06f11ca2c9c4e9795617de07ca1c541" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Common Shares</div>
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    </table>
    <div><font style="font-family: 'Times New Roman'; font-weight: bold;"> </font><br>
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    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z71bb5798aabd4a778d73c33aa948001b" cellpadding="0" cellspacing="0">

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          <td style="width: 72pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Item 2(e)</td>
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            <div style="font-family: 'Times New Roman'; font-weight: bold;">CUSIP Number: </div>
          </td>
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    <div> <br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zc01eb49652704e2b94d1bfdf0acffa74" cellpadding="0" cellspacing="0">

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            <div style="font-family: 'Times New Roman';">2966H104</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zdd10157bd6454024a4b446979ef873ec" cellpadding="0" cellspacing="0">

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          <td style="width: 72pt; vertical-align: top; align: right; font-family: 'Times New Roman'; font-weight: bold;">Item 3.</td>
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            <div style="font-family: 'Times New Roman'; font-weight: bold;">If this Statement is filed Pursuant to Rule 13d-1(b), or 13d-2(b) or (c), check whether the person filing is</div>
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            <td style="width: 72pt; vertical-align: top;">&#160;</td>
            <td style="width: 36pt; vertical-align: top;">&#160;</td>
            <td style="width: 36pt; vertical-align: top;">&#160;</td>
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            <td style="width: 72pt; vertical-align: top;">&#160;</td>
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              <div style="font-family: 'Times New Roman';">(b)</div>
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              <div style="font-family: 'Segoe UI Symbol', sans-serif;">&#9744;</div>
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              <div style="font-family: 'Times New Roman';">Bank as defined in Section 3(a) (6) of the Exchange Act;</div>
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            <td style="width: 72pt; vertical-align: top;">&#160;</td>
            <td style="width: 36pt; vertical-align: top;">&#160;</td>
            <td style="width: 36pt; vertical-align: top;">&#160;</td>
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            <td style="width: 72pt; vertical-align: top;">&#160;</td>
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              <div style="font-family: 'Times New Roman';">(c)</div>
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              <div style="font-family: 'Segoe UI Symbol', sans-serif;">&#9744;</div>
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              <div style="font-family: 'Times New Roman';">Insurance company as defined in Section 3(a) (19) of the Exchange Act;</div>
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            <td style="width: 72pt; vertical-align: top;">&#160;</td>
            <td style="width: 36pt; vertical-align: top;">&#160;</td>
            <td style="width: 36pt; vertical-align: top;">&#160;</td>
            <td style="vertical-align: top;">&#160;</td>
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          <tr>
            <td style="width: 72pt; vertical-align: top;">&#160;</td>
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              <div style="font-family: 'Segoe UI Symbol', sans-serif;">&#9744;</div>
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              <div style="font-family: 'Times New Roman';">Investment company registered under Section 8 of the Investment Company Act;</div>
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            <td style="width: 72pt; vertical-align: top;">&#160;</td>
            <td style="width: 36pt; vertical-align: top;">&#160;</td>
            <td style="width: 36pt; vertical-align: top;">&#160;</td>
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          <tr>
            <td style="width: 72pt; vertical-align: top;">&#160;</td>
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              <div style="font-family: 'Times New Roman';">(e)</div>
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              <div style="font-family: 'Segoe UI Symbol', sans-serif;">&#9744;</div>
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              <div style="font-family: 'Times New Roman';">An investment adviser in accordance with Rule 13d-1(b) (1) (ii) (E);</div>
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            <td style="width: 72pt; vertical-align: top;">&#160;</td>
            <td style="width: 36pt; vertical-align: top;">&#160;</td>
            <td style="width: 36pt; vertical-align: top;">&#160;</td>
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              <div style="font-family: 'Segoe UI Symbol', sans-serif;">&#9744;</div>
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              <div style="font-family: 'Times New Roman';">An employee benefit plan or endowment fund in accordance with Rule 13d-1(b) (1) (ii) (F);</div>
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            <td style="width: 36pt; vertical-align: top;">&#160;</td>
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            <td style="width: 72pt; vertical-align: top;">&#160;</td>
            <td style="width: 36pt; vertical-align: top;">&#160;</td>
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              <div style="font-family: 'Times New Roman';"><font style="font-weight: bold;">CUSIP No. </font>29668H104</div>
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              <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">13G/A</div>
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            <td style="width: 33%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">&#160;</td>
          </tr>

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              <td style="width: 36pt; vertical-align: top; align: right;"><font style="font-family: 'Times New Roman';">(i)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" id="TRGRRTFtoHTMLTab">&#160;</font></td>
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              <td style="width: auto; vertical-align: top; text-align: justify; font-family: 'Times New Roman';">A church plan that is excluded from the definition of an investment company under Section 3(c) (14) of the Investment Company Act;</td>
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            <div style="font-family: 'Times New Roman';">Not applicable.</div>
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    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z43793db0a9eb45039ea97f0c9b217738" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right; font-family: 'Times New Roman'; font-weight: bold;">Item 4.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Ownership.</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z677058a2677c423abb7522d746efb9aa" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';"><font style="font-weight: bold;">(a) Amount Beneficially Owned</font>:&#160; The Reporting Person is the general partner of each of Soleus Master Fund and Soleus Special Fund (the &#8220;Funds&#8221;), which
              collectively hold an aggregate of 3,474,658 common shares (the &#8220;Shares&#8221;) of the Issuer, including an aggregate of 1,098,977 common shares issuable upon exercise of certain warrants (&#8220;Warrants&#8221;) to purchase common shares within 60 days of the
              date of this Report.&#160; As the general partner of the Funds, the Reporting Person may be deemed to have sole power to vote or direct the vote and to dispose or to direct the disposition of the Shares.&#160; As the sole general partner of the
              Reporting Person, Soleus Group may be deemed to have shared power to vote or to direct the vote and to dispose or direct the disposition the Shares.&#160; The sole managing member of Soleus Group is Mr. Guy Levy, who may be deemed to have shared
              power to vote or direct the vote and to dispose or to direct the disposition of the Shares. Neither the filing of this Schedule 13G/A nor any of its contents shall be deemed to constitute an admission that Mr. Levy or Soleus Group is the
              beneficial owner of the Common Stock referred to herein for purposes of Section&#160;13(d) of the Securities Exchange Act of 1934, as amended, or for any other purpose, and such beneficial ownership is expressly disclaimed.</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zddcd8795b0dd4c4b86afe5fbde1b9bf3" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';"><font style="font-weight: bold;">(b)&#160; &#160; &#160;&#160; Percent of Class</font>:&#160; 9.99%, based on a total of 33,682,383 common shares outstanding as of January 13, 2021 as reported by the Issuer.</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="za189bc7d5d144a30a680df8c7130809d" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';"><font style="font-weight: bold;">(c)&#160; &#160; &#160;&#160; Number of shares as to which the Reporting Person has</font>:&#160; See Item 4(a) above.</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z2bba0f45ce9e47349a86a48dc58d8344" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right; font-family: 'Times New Roman'; font-weight: bold;">Item 5.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Ownership of Five Percent or Less of a Class.</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z8b7212e8e121478d8bf76bb966be38d2" cellpadding="0" cellspacing="0">

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          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Not Applicable</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zd9ff8c70b0094d2bb22c54d14f09c44f" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right; font-family: 'Times New Roman'; font-weight: bold;">Item 6.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Ownership of More than Five Percent on Behalf of Another Person.</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zf889df4d5268461b938687e8a65a6b2d" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Not Applicable</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z5dc25957ede1479aadfc0b692557e643" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right; font-family: 'Times New Roman'; font-weight: bold;">Item 7.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Identification and Classification of the Subsidiary Which Acquired the Security&#160; Being Reported on by the Parent Holding Company or Control Person.</div>
          </td>
        </tr>

    </table>
    <div> <br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zed74548daa5a4745bf960ea67194d309" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Not Applicable</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z4e7ab9fa1136452b8821e5a4f8c82238" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right; font-family: 'Times New Roman'; font-weight: bold;">Item 8.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Identification and Classification of Members of the Group.</div>
          </td>
        </tr>

    </table>
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    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zc6766568885344dfa83641ff3008c3ed" cellpadding="0" cellspacing="0">

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          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Not Applicable</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z2e9cd28c99b94ee781b564384a8c5071" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; align: right; font-family: 'Times New Roman'; font-weight: bold;">Item 9.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Notice of Dissolution of Group.</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zce830ef5e94c417d983a8877e7f5bf39" cellpadding="0" cellspacing="0">

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          <td style="width: 72pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Not Applicable</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z573697796db349e0a58e8d126851c5e6" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 72pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Item 10.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Certifications.</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zcc7749aa49cd4e07918a0a48fc95f386" cellpadding="0" cellspacing="0">

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          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Not Applicable</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <div>&#160;</div>
    <div style="text-align: center; font-family: 'Times New Roman';">[<font style="font-style: italic;">The remainder of this page intentionally left blank</font>]</div>
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              <div style="font-family: 'Times New Roman';"><font style="font-weight: bold;">CUSIP No. </font>29668H104</div>
            </td>
            <td style="width: 34%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">13G/A</div>
            </td>
            <td style="width: 33%; vertical-align: top; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">&#160;</td>
          </tr>

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    <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;"> <br>
    </div>
    <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;"> <br>
    </div>
    <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">SIGNATURE</div>
    <div><br>
    </div>
    <div style="text-align: justify; text-indent: 36pt; font-family: 'Times New Roman';">After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.</div>
    <div><br>
    </div>
    <div><br>
    </div>
    <div style="text-align: justify; font-family: 'Times New Roman';">Date:&#160; February 12, 2021</div>
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        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">
            <div style="text-indent: -12pt; margin-left: 12pt; font-family: 'Times New Roman'; font-weight: bold;">Soleus Capital, LLC,</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;" nowrap="nowrap">
            <div style="font-family: 'Times New Roman';">By: Soleus Capital Group, LLC, its general partner</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: middle;">&#160;</td>
        </tr>
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          <td style="width: 50%; vertical-align: top; padding-bottom: 1px;">&#160;</td>
          <td style="width: 50%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">/s/ Steven Musumeci</td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: bottom;">
            <div style="font-family: 'Times New Roman';">Name: Steven Musumeci</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Title: Authorized Person</div>
          </td>
        </tr>

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    <div>&#160;</div>
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</DOCUMENT>
</SEC-DOCUMENT>
