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SHAREHOLDERS EQUITY (Tables)
6 Months Ended
Mar. 31, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Summary of Warrants Activity

Warrant transactions are summarized as follows:

    

    

Weighted

Number

Average

of Warrants

Exercise Price

 

Balance, September 30, 2021 and September 30, 2022

 

3,234,750

$

4.84

Warrants expired

 

(307,273)

 

(49.86)

Balance outstanding and exercisable, March 31, 2023

 

2,927,477

$

0.11

Summary of Warrants Outstanding

Number

    

    

of Warrants

Exercise Price

Expiry Date

7,477

  

$

42.80

 

November 18, 2023

2,920,000

$

0.0001

 

August 23, 2024

2,927,477

  

  

 

  

Employee Share Purchase Plan [Member]  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Schedule of Share Based Compensation Expense

During the six months ended March 31, 2023, the Company issued 19,298 shares (2022 – 2,444) upon the exercise of Purchase Rights. The Company recognizes compensation expense for purchase rights on a straight-line basis over the service period.

For the three months ended

For the six months ended

March 31, 

March 31, 

    

2023

    

2022

    

2023

    

2022

Research and development expense

$

754

 

$

8,483

$

1,352

 

$

12,133

General and administrative

 

41

 

805

 

494

 

6,957

$

795

$

9,288

$

1,846

$

19,090

Weighted Average Assumptions for the Valuation of Stock Options

The Company measures the purchase rights based on their estimated grant date fair value using the Black-Scholes option pricing model and the estimated number of shares that can be purchased. The following weighted average assumptions were used for the valuation of purchase rights:

2023

    

2022

    

Risk-free interest rate

 

3.19

%  

0.44

%  

Expected life of share purchase rights

 

6 months

 

6 months

 

Expected annualized volatility

 

103.56

%  

87.90

%  

Dividend

 

 

 

Stock Options Plan [Member]  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Schedule of Share Based Compensation Expense

The Company recognized share-based payments expense for options granted and vesting, net of recoveries on cancellations of unvested options, during the period ended March 31, 2023 and 2022 with allocations to its functional expense as follows:

For the three months ended

For the six months ended

March 31, 

March 31, 

2023

    

2022

2023

    

2022

Research and development expense

$

749,405

 

$

1,113,376

$

1,539,999

 

$

2,369,077

General and administrative

 

686,891

 

740,689

 

1,458,857

 

1,975,277

$

1,436,296

 

$

1,854,065

$

2,998,856

 

$

4,344,354

Weighted Average Assumptions for the Valuation of Stock Options

The following weighted average assumptions were used for the Black-Scholes option-pricing model valuation of stock options granted:

2023

    

2022

Risk-free interest rate

 

3.97

%  

1.20

%

Expected life of options

 

10.00

years

10.00

years

Expected annualized volatility

 

79.00

%  

80.00

%

Dividend

 

 

Summary of Stock Option Activity

Stock option transactions are summarized as follows:

    

    

Weighted

Number

Average

of Options

Exercise Price*

 

Balance, September 30, 2021

 

6,803,230

$

5.20

Options granted

 

1,347,500

 

4.55

Options exercised

(72,910)

(4.41)

Options expired/forfeited

 

(175,759)

 

(3.60)

Balance, September 30, 2022

 

7,902,061

$

5.13

Options granted

 

195,000

 

3.00

Options expired/forfeited

 

(51,787)

 

(5.03)

Balance outstanding, March 31, 2023

 

8,045,274

$

5.08

Balance exercisable, March 31, 2023

 

5,302,472

$

4.83

*Options exercisable in Canadian dollars as of March 31, 2023 are translated at current rates to reflect the current weighted average exercise price in US dollars for all outstanding options.
Summary of Stock Option Outstanding

At December 31, 2022, options were outstanding enabling holders to acquire common shares as follows:

    

Weighted average remaining

Exercise price

Number of options

contractual life (years)

$

2.39

50,000

9.46

$

2.91

175,000

9.83

$

3.23

3,629,400

6.52

$

3.59

26,667

 

6.55

$

3.60

922,500

 

9.25

$

3.75

20,000

 

9.68

$

3.81

185,816

 

5.87

$

4.00

539,518

 

4.73

$

4.67

168,227

 

6.59

$

5.99

190,000

 

9.07

$

7.00

1,458,646

 

7.70

$

8.47

120,000

 

8.54

$

9.76

50,000

 

8.89

$

13.96

190,000

 

7.79

$

29.63

100,000

 

8.08

$

31.62

75,000

 

8.17

C$

4.90

124,500

 

4.13

C$

5.06

20,000

 

5.87

8,045,274

 

7.15