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Stockholders' Equity (Details Narrative) - USD ($)
 1 Months Ended 3 Months Ended 9 Months Ended
Dec. 18, 2015
Jun. 29, 2015
Jun. 17, 2015
Mar. 26, 2015
Jun. 29, 2015
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Dec. 31, 2015
Dec. 31, 2014
Common stock, shares authorized   25,000,000     25,000,000 25,000,000   25,000,000   25,000,000 50,000,000
Common stock, par value   $ 0.001     $ 0.001 $ 0.001   $ 0.001   $ 0.001 $ 0.001
Reverse stock split description     1-for-7.15 reverse stock split                
Common stock, shares issued           8,592,912   8,592,912   8,582,004  
Common stock, shares outstanding           8,592,912   8,592,912   8,582,004  
Aggregate gross proceeds from sale of common stock               $ 20,000,000    
Warrants exercise price           $ 8.45   $ 8.45   $ 8.45  
Preferred stock, shares authorized           5,000,000   5,000,000   5,000,000  
Preferred stock, par value           $ 0.001   $ 0.001   $ 0.001  
Payments to research and development           $ 2,348,755 $ 1,505,116 $ 7,112,177 $ 1,584,086    
Series A-1 Preferred Stock Member                      
Shares of common stock sold, per share           $ 0.07   $ 0.07      
Preferred stock, shares authorized           7,200,000   7,200,000      
Preferred stock, par value           $ 0.001   $ 0.001      
Preferred stock annual dividend rate per share               0.00556      
Preferred stock liquidation preference, per share           0.07   0.07      
Series A-2 Preferred Stock [Member]                      
Shares of common stock sold, per share           $ 0.40   $ 0.40      
Preferred stock, shares authorized           1,687,500   1,687,500      
Preferred stock, par value           $ 0.001   $ 0.001      
Preferred stock annual dividend rate per share               0.032      
Preferred stock liquidation preference, per share           0.40   0.40      
Series A-3 Preferred Stock [Member]                      
Shares of common stock sold, per share           $ 0.62   $ 0.62      
Preferred stock, shares authorized           4,220,464   4,220,464      
Preferred stock, par value           $ 0.001   $ 0.001      
Preferred stock redemption price per share           0.62   0.62      
Preferred stock annual dividend rate per share               0.04957      
Preferred stock liquidation preference, per share           0.62   0.62      
Series B Preferred Stock [Member]                      
Shares of common stock sold, per share           $ 1.19   $ 1.19      
Preferred stock, shares authorized           7,658,182   7,658,182      
Preferred stock, par value           $ 0.001   $ 0.001      
Preferred stock redemption price per share           1.19   1.19      
Preferred stock annual dividend rate per share               0.09524      
Preferred stock undeclared dividends in arrears   $ 2,000,000                  
Preferred stock liquidation preference, per share           1.19   1.19      
Series C Preferred Stock [Member]                      
Shares of common stock sold, per share           $ 1.30   $ 1.30      
Aggregate of shares issued during period               3,322,652      
Preferred stock, shares authorized           4,500,000   4,500,000      
Preferred stock, par value           $ 0.001   $ 0.001      
Preferred stock redemption price per share           1.30   1.30      
Preferred stock annual dividend rate per share               0.104      
Preferred stock liquidation preference, per share           1.30   $ 1.30      
Kolu Pohaku Management And Kolu Pohaku Technologies [Member] | Research And Development Agreement & License [Member]                      
Payments to research and development               $ 1,750,000      
Kolu Pohaku Technologies [Member] | Research And Development Agreement & License [Member]                      
Payment to royalty               $ 32,000      
Exercised period term               March 31, 2015 and continuing through December 31, 2035      
Kolu Pohaku Technologies [Member] | Series B Preferred Stock [Member] | Option Agreement [Member]                      
Payments to research and development               $ 1,750,000      
Original shares issued price per share           1.19   $ 1.19      
Aggregate converted shares of the common stock upon the closing of the IPO       1,469,994              
Shares issued               1,469,994      
Kolu Pohaku Management [Member] | Research And Development Agreement & License [Member]                      
Payment to royalty       $ 1,469,994              
Common Stock Purchase Agreement [Member] | Aspire Capital Fund LLC [Member]                      
Number of common shares sold 500,000             888,835      
Shares of common stock sold, per share $ 2.00         0.50   $ 0.50      
Payments to acquire common stock $ 10,000,000             $ 9,000,000      
Purchase agreement term 30 months                    
Aggregate of shares issued during period 188,864             100,000      
Number of stock sold during period, value $ 1,000,000                    
IPO [Member]                      
Number of common shares sold   4,000,000     4,000,000            
Shares of common stock sold, per share   $ 5.00     $ 5.00            
Aggregate gross proceeds from sale of common stock   $ 20,000,000                  
Underwriting discounts and commissions   1,600,000     $ 1,600,000            
Other expenses with offering   1,000,000                  
Underwriters paid an aggregate purchase price   $ 100                  
Warrant issued to purchase number of common stock   160,000                  
Percentage of initial public offering shares   4.00%                  
Warrants exercise price   $ 6.25     $ 6.25            
Percentage of warrants exercise price equal to initial public offering price   125.00%                  
Warrants exercisable expiration   June 29, 2016 and expire on June 29, 2020                  
Number of preferred stock and preferred stock subject to redemption converted into common stock (in shares)   3,322,652     3,322,652            
Aggregate converted shares of the common stock upon the closing of the IPO               205,593      
October 2016 Public Offering [Member]                      
Number of common shares sold               2,127,660      
Shares of common stock sold, per share           $ 2.35   $ 2.35      
Aggregate gross proceeds from sale of common stock               $ 5,000,000      
Underwriting discounts and commissions               400,000      
Other expenses with offering               200,000      
October 2016 Public Offering [Member] | Maximum [Member]                      
Aggregate gross proceeds from sale of common stock               150,000,000      
Debt securities issued               $ 150,000,000      
Over-Allotment Option [Member]                      
Number of common shares sold               212,766      
Aggregate gross proceeds from sale of common stock               $ 5,100,000      
Underwriting discounts and commissions               $ 400,000