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Statements of Cash Flows - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2019 | Dec. 31, 2018
Cash flows from operating activities |  |  |
Net loss |  | $ (10,133,019) | $ (16,868,711)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation |  | 6,093 | 5,721
Amortization of right-of-use assets |  | 105,287 |
Stock-based compensation |  | 438,248 | 645,823
Settlement of accounts payable | [1] | 588,114 | 893,823
Amortization of discount on available-for-sale debt securities |  | (9,769) | (19,789)
Change in unrealized gain (loss) on investment in marketable debt securities |  | 923 | (923)
Changes in operating assets and liabilities: |  |  |
Accrued interest receivable |  | 53,685 | (54,456)
Prepaid expenses and other current assets |  | (87,997) | (254,122)
Other assets |  | (455,350) | (12,399)
Accounts payable |  | (2,506,885) | 3,168,559
Accrued expenses |  | (1,228,585) | 953,591
Lease liabilities |  | (97,848) |
Other liabilities |  | (13,359) | (2,398)
Net cash and cash equivalents used in operating activities |  | (14,516,690) | (13,332,927)
Cash flows from investing activities |  |  |
Purchase of property and equipment |  | (1,589) | (2,008)
Purchase of investment in marketable securities |  |  | (6,968,991)
Sale of investments in marketable debt securities |  | 6,998,549 |
Net cash and cash equivalents provided by (used) in investing activities |  | 6,996,960 | (6,970,999)
Cash flows from financing activities |  |  |
Proceeds from the issuance of preferred shares upon closing of private placement |  |  | 6,000,000
Commission and issuance costs of private placement |  |  | (512,530)
Proceeds from the issuance of shares from ATM Agreement |  | 1,457,068 |
Stock issuance costs of ATM Agreement |  | (49,626) |
Payout to shareholders for fractional shares |  |  | (3,256)
Net cash and cash equivalents provided by financing activities |  | 1,407,442 | 5,484,214
Net decrease in cash and cash equivalents |  | (6,112,288) | (14,819,712)
Cash and cash equivalents at beginning of year |  | 7,812,259 | 22,631,971
Cash and cash equivalents at end of year |  | 1,699,971 | 7,812,259
Supplemental disclosure of cash flow activities: |  |  |
Cash paid for taxes |  | 187,095 | 2,233
Supplemental disclosure of non-cash investing and financing activities: |  |  |
Deemed dividend on preferred stock |  |  | 2,537,844
Conversion of preferred stock to common stock |  | 6,547,299 | 2,057,794
Conversion of Series A preferred stock to Series C preferred stock |  |  | 1,880,000
Right-of-use assets obtained in exchange for lease liabilities |  | (198,319) |
Lease liabilities arising from obtaining right-of-use assets |  | $ 100,471 |
[1] | For comparative presentation purposes, settlement of accounts payable of $893,823 for the year ended December 31, 2018 was reclassified out of research and development and into settlement of accounts payable under other income.

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