<SEC-DOCUMENT>0001140361-21-019770.txt : 20210603
<SEC-HEADER>0001140361-21-019770.hdr.sgml : 20210603
<ACCEPTANCE-DATETIME>20210603172140
ACCESSION NUMBER:		0001140361-21-019770
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		5
FILED AS OF DATE:		20210603
DATE AS OF CHANGE:		20210603
EFFECTIVENESS DATE:		20210603

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Brooklyn ImmunoTherapeutics, Inc.
		CENTRAL INDEX KEY:			0000748592
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				311103425
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-256760
		FILM NUMBER:		21993612

	BUSINESS ADDRESS:	
		STREET 1:		140 58TH STREET, BUILDING A
		STREET 2:		SUITE 2100
		CITY:			BROOKLYN
		STATE:			NY
		ZIP:			11220
		BUSINESS PHONE:		(212) 582-1199

	MAIL ADDRESS:	
		STREET 1:		140 58TH STREET, BUILDING A
		STREET 2:		SUITE 2100
		CITY:			BROOKLYN
		STATE:			NY
		ZIP:			11220

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NTN BUZZTIME INC
		DATE OF NAME CHANGE:	20051230

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NTN COMMUNICATIONS INC
		DATE OF NAME CHANGE:	19920703

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ALROY INDUSTRIES INC
		DATE OF NAME CHANGE:	19850411
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>brhc10025341_s8.htm
<DESCRIPTION>S-8
<TEXT>
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    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">As filed with the Securities and Exchange Commission on June 3, 2021.</div>
    <div style="text-align: right; color: rgb(0, 0, 0); font-weight: bold;">Registration No. 333-</div>
    <div style="text-align: right; color: rgb(0, 0, 0); font-weight: bold;">
      <hr align="center" style="border: none; border-bottom: 1px solid black; border-top: 4px solid black; height: 10px; color: #ffffff; background-color: #ffffff; text-align: center; margin-left: auto; margin-right: auto;"> </div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-size: 14pt; font-weight: bold;">UNITED STATES SECURITIES AND EXCHANGE COMMISSION</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">
      <div style="color: rgb(0, 0, 0); font-size: 12pt; font-weight: bold;">WASHINGTON, D.C. 20549</div>
    </div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;"> <br>
    </div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">
      <hr noshade="noshade" align="center" style="background-color: #000000; border-bottom: medium none; border-left: medium none; border-right: medium none; border-top: medium none; margin: 0px auto; height: 2px; width: 18%; color: #000000;"></div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;"> <br>
    </div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-size: 18pt; font-weight: bold;">FORM S-8</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;"> <br>
    </div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">
      <hr noshade="noshade" align="center" style="background-color: #000000; border-bottom: medium none; border-left: medium none; border-right: medium none; border-top: medium none; margin: 0px auto; height: 2px; width: 18%; color: #000000;"></div>
    <div><br>
    </div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-size: 24pt; font-weight: bold;">BROOKLYN IMMUNOTHERAPEUTICS, INC.</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-style: italic;">(Exact name of registrant as specified in its charter)</div>
    <div>&#160;</div>
    <table cellspacing="0" cellpadding="0" id="z39464eaad9114b90931f718af17bfdbc" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

        <tr>
          <td style="width: 49.01%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Delaware</div>
          </td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">31-1103425</div>
          </td>
        </tr>
        <tr>
          <td style="width: 49.01%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-style: italic;">(State or other jurisdiction of incorporation or organization)</div>
          </td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-style: italic;">(I.R.S. Employer Identification Number)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 100%; vertical-align: top;" colspan="3">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;"><br>
              140 58th Street, Suite 2100</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Brooklyn, New York 11220</div>
          </td>
        </tr>
        <tr>
          <td style="width: 100%; vertical-align: top; text-align: center;" colspan="3">
            <div style="color: rgb(0, 0, 0); font-style: italic;">(Address, including zip code, of registrant&#8217;s principal executive offices)</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <div>
      <hr noshade="noshade" align="center" style="background-color: #000000; border-bottom: medium none; border-left: medium none; border-right: medium none; border-top: medium none; margin: 0px auto; height: 2px; width: 18%; color: #000000; text-align: center;"></div>
    <div>&#160;</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">2020 Stock Incentive Plan</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">2021 Inducement Stock Incentive Plan</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Executive Employment Agreement dated as of April 1, 2021 with Howard J. Federoff</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-style: italic;">&#160;(Full title of the plan)</div>
    <div><br>
    </div>
    <div>
      <hr noshade="noshade" align="center" style="background-color: #000000; border-bottom: medium none; border-left: medium none; border-right: medium none; border-top: medium none; margin: 0px auto; height: 2px; width: 18%; color: #000000; text-align: center;"></div>
    <div>&#160;</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Howard J. Federoff</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Chief Executive Officer and President</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Brooklyn ImmunoTherapeutics, Inc.</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">140 58th Street, Suite 2100</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Brooklyn, New York 11220</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Telephone: (212) 582-1199</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-style: italic;">(Name, address, including zip code, and telephone number, including area code, of agent for service)</div>
    <div>&#160;</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-style: italic;">Copy to:</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Mark L. Johnson</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Bella Zaslavsky</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">K&amp;L Gates LLP</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">One Lincoln Street</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Boston, Massachusetts 02111</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">(617) 261-3260</div>
    <div><br>
    </div>
    <div>
      <hr noshade="noshade" align="center" style="background-color: #000000; border-bottom: medium none; border-left: medium none; border-right: medium none; border-top: medium none; margin: 0px auto; height: 2px; width: 18%; color: #000000; text-align: center;"></div>
    <div> <br>
    </div>
    <div style="text-align: justify; color: rgb(0, 0, 0);">Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the
      definitions of &#8220;large accelerated filer,&#8221; &#8220;accelerated filer,&#8221; &#8220;smaller reporting company&#8221; and &#8220;emerging growth company&#8221; in Rule 12b-2 of the Exchange Act.</div>
    <table cellspacing="0" cellpadding="0" border="0" id="za592ceb9facd4ef5938e00fdc09321f5" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: rgb(0, 0, 0);">

        <tr>
          <td style="width: 37.3%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0);">Large accelerated filer</div>
          </td>
          <td style="width: 15.41%; vertical-align: top;">&#9744;</td>
          <td style="width: 23.64%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0);">Accelerated filer</div>
          </td>
          <td style="width: 23.66%; vertical-align: top; text-align: right;">&#9744;</td>
        </tr>
        <tr>
          <td style="width: 37.3%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0);">Non-accelerated filer</div>
          </td>
          <td style="width: 15.41%; vertical-align: top;">&#9746;</td>
          <td style="width: 23.64%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0);">Smaller reporting company</div>
          </td>
          <td style="width: 23.66%; vertical-align: top; text-align: right;">&#9746;</td>
        </tr>
        <tr>
          <td style="width: 37.3%; vertical-align: top;">&#160;</td>
          <td style="width: 15.41%; vertical-align: top;">&#160;</td>
          <td style="width: 23.64%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0);">Emerging growth company</div>
          </td>
          <td style="width: 23.66%; vertical-align: top; text-align: right;">&#9744;</td>
        </tr>

    </table>
    <div style="color: rgb(0, 0, 0);">If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revise financial accounting standards provided pursuant to
      Section 7(a)(2)(B) of the Securities Act. &#9744;</div>
    <div>&#160;</div>
    <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; text-align: left; color: #000000; width: 100%;" id="zb34ed1a3a4394d2d98645bfa79268282">

        <tr>
          <td valign="bottom" style="vertical-align: bottom; border-bottom: 4px double rgb(0, 0, 0);" rowspan="1" colspan="8">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">CALCULATION OF REGISTRATION FEE</div>
          </td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: bottom; border-right: 2px solid rgb(0, 0, 0); border-bottom: 2px solid rgb(0, 0, 0); width: 27%;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Title of Securities to be Registered</div>
          </td>
          <td valign="bottom" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); width: 1%;" colspan="1">&#160;</td>
          <td valign="bottom" nowrap="nowrap" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);" colspan="2">
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: &#38;quot; font-weight: bold;">Amount to be</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: &#38;quot; font-weight: bold;">Registered(1)</div>
          </td>
          <td valign="bottom" nowrap="nowrap" style="vertical-align: bottom; border-right: 2px solid rgb(0, 0, 0); border-bottom: 2px solid rgb(0, 0, 0); width: 1%;" colspan="1">&#160;</td>
          <td valign="bottom" style="vertical-align: bottom; border-right: 2px solid rgb(0, 0, 0); border-bottom: 2px solid rgb(0, 0, 0); width: 20%;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Proposed Maximum <br>
            </div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Offering Price Per </div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Share(2)</div>
          </td>
          <td valign="bottom" style="vertical-align: bottom; border-right: 2px solid rgb(0, 0, 0); border-bottom: 2px solid rgb(0, 0, 0); width: 20%;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: &#38;quot; font-weight: bold;">Proposed Maximum</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: &#38;quot; font-weight: bold;">Aggregate Offering</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: &#38;quot; font-weight: bold;"> Price(2)</div>
          </td>
          <td valign="bottom" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); width: 21%;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: &#38;quot; font-weight: bold;">Amount of</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: &#38;quot; font-weight: bold;">Registration Fee</div>
          </td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: middle; width: 27%; border-right: 2px solid rgb(0, 0, 0); background-color: rgb(204, 238, 255); border-bottom: 4px double rgb(0, 0, 0);">
            <div style="color: rgb(0, 0, 0); text-indent: -9pt; margin-left: 9pt;">Common stock, $0.005 par value per share</div>
          </td>
          <td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: rgb(204, 238, 255); border-bottom: 4px double rgb(0, 0, 0);" colspan="1">&#160;</td>
          <td valign="bottom" style="vertical-align: bottom; width: 1%; border-bottom: 4px double rgb(0, 0, 0); background-color: rgb(204, 238, 255);" colspan="1">&#160;</td>
          <td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: 4px double rgb(0, 0, 0); background-color: rgb(204, 238, 255);" colspan="1">
            <div style="color: rgb(0, 0, 0);">8,093,972</div>
          </td>
          <td valign="bottom" nowrap="nowrap" style="vertical-align: bottom; width: 1%; border-right: 2px solid rgb(0, 0, 0); background-color: rgb(204, 238, 255); border-bottom: 4px double rgb(0, 0, 0);" colspan="1">&#160;</td>
          <td valign="bottom" style="vertical-align: middle; width: 20%; border-right: 2px solid rgb(0, 0, 0); background-color: rgb(204, 238, 255); border-bottom: 4px double rgb(0, 0, 0);">
            <div style="text-align: center; color: rgb(0, 0, 0);">$14.185</div>
          </td>
          <td valign="bottom" style="vertical-align: middle; width: 20%; border-right: 2px solid rgb(0, 0, 0); background-color: rgb(204, 238, 255); border-bottom: 4px double rgb(0, 0, 0);">
            <div style="text-align: center; color: rgb(0, 0, 0);">$114,812,992.82</div>
          </td>
          <td valign="bottom" style="vertical-align: middle; width: 21%; background-color: rgb(204, 238, 255); border-bottom: 4px double rgb(0, 0, 0);">
            <div style="text-align: center; color: rgb(0, 0, 0);">$12,526.10</div>
          </td>
        </tr>

    </table>
    <table cellspacing="0" cellpadding="0" id="zaf74a89c212c4dc8a2dfe932833dff60" class="DSPFListTable" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

        <tr>
          <td style="width: 18pt; vertical-align: top; color: rgb(0, 0, 0);">(1)</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div style="color: rgb(0, 0, 0);">Consists of (a) 3,368,804 shares authorized for issuance under the registrant&#8217;s 2020 Stock Incentive Plan, (b) 1,500,000 shares authorized for issuance under the registrant&#8217;s 2021 Inducement Stock Incentive
              Plan and (c) 3,225,168 shares authorized for issuance under the registrant&#8217;s Executive Employment Agreement dated as of April 1, 2021 with Howard J. Federoff. In accordance with Rule 416 under the Securities Act of 1933, this registration
              statement shall be deemed to cover any additional securities that may from time to time be offered or issued to prevent dilution resulting from stock splits, stock dividends or similar transactions.</div>
          </td>
        </tr>

    </table>
    <table cellspacing="0" cellpadding="0" id="zc6dd1041c374445881888574640a31b7" class="DSPFListTable" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

        <tr>
          <td style="width: 18pt; vertical-align: top; color: rgb(0, 0, 0);">(2)</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div style="color: rgb(0, 0, 0);">
              <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif;">Estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and (h) under the Securities Act of 1933 and based upon
                the average of the high and low prices of the registrant&#8217;s common stock as reported on the NYSE American on May 26, 2021.</div>
            </div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <div>
      <hr align="center" style="border: none; border-bottom: 4px solid black; border-top: 1px solid black; height: 10px; color: #ffffff; background-color: #ffffff; text-align: center; margin-left: auto; margin-right: auto;"></div>
    <div id="DSPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div id="DSPFPageFooter"></div>
      <div id="DSPFPageBreak" style="page-break-after:always;">
        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
      <div id="DSPFPageHeader"></div>
    </div>
    <div style="text-align: justify; margin-right: 0.1pt; margin-left: 0.1pt; color: rgb(0, 0, 0);">This Registration Statement on Form S-8 is being filed by Brooklyn ImmunoTherapeutics, Inc. (the &#8220;Company&#8221;) for the purpose of registering (a) 3,368,804
      shares of the Company&#8217;s common stock, $0.005 par value per share (&#8220;Common Stock&#8221;), authorized for issuance under the Company&#8217;s 2020 Stock Incentive Plan, (b) 1,500,000 shares of Common Stock authorized for issuance under the Company&#8217;s Inducement
      Stock Incentive Plan and (c) 3,225,168 shares of Common Stock authorized for issuance under the Executive Employment Agreement dated as of April 1, 2021 between the Company and Howard J. Federoff. Such 2020 Stock Incentive Plan, such 2021 Inducement
      Stock Incentive Plan and such Executive Employment Agreement and are referred to below collectively as the &#8220;Plans.&#8221;</div>
    <div>&#160;</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">PART I</div>
    <div>&#160;</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</div>
    <div>&#160;</div>
    <table cellspacing="0" cellpadding="0" id="z3af3032c7860474199c024c1047c2627" class="DSPFListTable" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

        <tr>
          <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-weight: bold;">Item 1.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-weight: bold;">Plan Information.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: justify; color: rgb(0, 0, 0);">The information required by Item 1 is included in documents sent or given by the Company to participants in the Plans pursuant to Rule 428(b)(1) of the Securities Act of 1933 (the &#8220;Securities
      Act&#8221;).</div>
    <div>&#160;</div>
    <table cellspacing="0" cellpadding="0" id="z5689f7b76c7f40d7b12207eb680f511f" class="DSPFListTable" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

        <tr>
          <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-weight: bold;">Item 2.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-weight: bold;">Registrant Information and Employee Plan Annual Information.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div>&#160;</div>
    <div style="text-align: justify; margin-right: 0.1pt; margin-left: 0.1pt; color: rgb(0, 0, 0);">The written statement required by Item 2 is included in documents sent or given by the Company to participants in the Plans pursuant to Rule 428(b)(1) of
      the Securities Act.</div>
    <div>&#160;</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">PART II</div>
    <div>&#160;</div>
    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</div>
    <div>&#160;</div>
    <table cellspacing="0" cellpadding="0" id="z0debc1b35632447883ed4fe9e3860932" class="DSPFListTable" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

        <tr>
          <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-weight: bold;">Item 3.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-weight: bold;">Incorporation of Documents by Reference.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: justify; color: rgb(0, 0, 0);">The following documents filed by the Company with the Securities and Exchange Commission are incorporated by reference in this registration statement:</div>
    <div>&#160;</div>
    <table cellspacing="0" cellpadding="0" id="z5d98792d4a824427851fee943799b870" class="DSPFListTable" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

        <tr>
          <td style="width: 18pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top; color: rgb(0, 0, 0);">(a)</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div style="color: rgb(0, 0, 0);">the&#160; latest annual report on Form <a href="https://www.sec.gov/Archives/edgar/data/748592/000149315221005827/form10-k.htm">10-K</a> of the Company filed pursuant to Section 13(a) or 15(d) of the Securities
              Exchange Act of 1934 (the &#8220;Exchange Act&#8221;) that contains audited financial statements for the Company&#8217;s latest fiscal year for which such statements have been filed;</div>
          </td>
        </tr>

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    <div>&#160;</div>
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        <tr>
          <td style="width: 18pt;"><br>
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            <div style="color: rgb(0, 0, 0);">all other reports filed by the Company pursuant to Section 13(a) or 15(d) of the Exchange Act since the end of the fiscal year covered by the annual report referred to in (a) above; and</div>
          </td>
        </tr>

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    <div>&#160;</div>
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        <tr>
          <td style="width: 18pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top; color: rgb(0, 0, 0);">(c)</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div style="color: rgb(0, 0, 0);">the description of the Common Stock set forth in <a href="https://www.sec.gov/Archives/edgar/data/748592/000114036121015372/nt10023650x1_ex4-2.htm">Exhibit 4.2</a> to the Company&#8217;s Registration Statement on
              Form S-1 filed with the SEC on April 30, 2021, together with any amendment or report filed with the SEC for the purpose of updating such description.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: justify; color: rgb(0, 0, 0);">All reports and other documents subsequently filed by the Company pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act prior to the filing of a post-effective amendment that
      indicates that all securities offered have been sold, or that deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference in this registration statement and to be part of this registration statement from the
      respective dates of the filing of such reports and other documents.</div>
    <div>&#160;</div>
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        <tr>
          <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-weight: bold;">Item 4.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-weight: bold;">Description of Securities.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: justify; color: rgb(0, 0, 0);">Not applicable.</div>
    <div>&#160;</div>
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        <tr>
          <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-weight: bold;">Item 5.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-weight: bold;">Interests of Named Experts and Counsel</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: justify; color: rgb(0, 0, 0);">K&amp;L Gates LLP has opined as to the legality of the shares of Common Stock being offered by this registration statement.</div>
    <div>&#160;</div>
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        <tr>
          <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-weight: bold;">Item 6.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-weight: bold;">Indemnification of Directors and Officers.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: justify; color: rgb(0, 0, 0);">Section 102 of the Delaware General Corporation Law permits a corporation to eliminate the personal liability of its directors for monetary damages for a breach of fiduciary duty as a director,
      except where the director breached his or her duty of loyalty, failed to act in good faith, engaged in intentional misconduct or knowingly violated a law, authorized the payment of a dividend or approved a stock repurchase in violation of the
      Delaware General Corporation Law or obtained an improper personal benefit. The Company&#8217;s restated certificate of incorporation provides that none of its directors shall be personally liable to the Company or its stockholders for monetary damages for
      any breach of fiduciary duty as a director, notwithstanding any provision of law imposing such liability, except for liability (i) for any breach of the director&#8217;s duty of loyalty to the corporation or its stockholders, (ii) for acts or omissions not
      in good faith or which involve intentional misconduct or a knowing violation of law, (iii) under section 174 of the Delaware General Corporation Law, or (iv) for any transaction from which the director derived an improper personal benefit.</div>
    <div>&#160;</div>
    <div style="text-align: justify; color: rgb(0, 0, 0);">Section 145 of the Delaware General Corporation Law provides that a corporation has the power to indemnify a director, officer, employee, or agent of the corporation and certain other persons
      serving at the request of the corporation in related capacities against expenses (including attorneys&#8217; fees), judgments, fines and amounts paid in settlements actually and reasonably incurred by the person in connection with an action, suit or
      proceeding to which he or she is or is threatened to be made a party by reason of such position, if such person acted in good faith and in a manner he or she reasonably believed to be in or not opposed to the best interests of the corporation, and,
      in any criminal action or proceeding, had no reasonable cause to believe his or her conduct was unlawful, except that, in the case of actions brought by or in the right of the corporation, no indemnification shall be made with respect to any claim,
      issue or matter as to which such person shall have been adjudged to be liable to the corporation unless and only to the extent that the Court of Chancery or other adjudicating court determines that, despite the adjudication of liability but in view
      of all of the circumstances of the case, such person is fairly and reasonably entitled to indemnity for such expenses which the Court of Chancery or such other court shall deem proper.</div>
    <div>&#160;</div>
    <div style="text-align: justify; color: rgb(0, 0, 0);">The Company&#8217;s restated certificate of incorporation provides that it will indemnify, in the manner and to the full extent permitted by law, any person (or the estate of any person) who was or is a
      party, or is threatened to be made a party to, any threatened, pending or completed action, suit or proceeding, whether or not by or in the right of the Company, and whether civil, criminal, administrative, investigative or otherwise, by reason of
      the fact that such person is or was a director, officer, employee or agent of the Company, or is or was serving at the request of the Company as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other
      enterprise. Where required by law, the indemnification provided for shall be made only as authorized in the specific case upon a determination in the manner provided by law, that indemnification of the director, officer, employee or agent is proper
      under the circumstances. The Company may, to the full extent permitted by law, purchase and maintain insurance on behalf of any such person against any liability which may be asserted against him. To the full extent permitted by law, the
      indemnification provided shall include expenses (including attorneys&#8217; fees) in any action, suit or proceeding, or in connection with any appeal therein, judgments, fines and amounts paid in settlement, and in the manner provided by law any such
      expenses may be paid by the Company in advance of the final disposition of such action, suit or proceeding. The indemnification described herein shall not be deemed limit the Company&#8217;s right to indemnify any other person for any such expense to the
      full extent permitted by law, nor shall it be deemed exclusive of any other rights to which any person seeking indemnification from the Company may be entitled under any agreement, vote of stockholders or disinterested directors or otherwise, both as
      to action in his or her official capacity and as to action in another capacity while holding such office.</div>
    <div>&#160;</div>
    <div style="text-align: justify; color: rgb(0, 0, 0);">The board of directors has approved a form of indemnification agreement that has been executed by each of the Company&#8217;s directors and executive officers. In general, these agreements each provide
      that the Company will indemnify the director or executive officer to the fullest extent permitted by law for claims arising in his or her capacity as a director or executive officer of the Company or in connection with their service at the Company&#8217;s
      request for another corporation or entity. The indemnification agreements also provide for procedures that will apply in the event that a director or executive officer makes a claim for indemnification and establish certain presumptions that are
      favorable to the director or executive officer.</div>
    <div>&#160;</div>
    <div style="text-align: justify; color: rgb(0, 0, 0);">The Company maintains a general liability insurance policy that covers certain liabilities of the Company&#8217;s directors and officers arising out of claims based on acts or omissions in their
      capacities as directors or officers.</div>
    <div>&#160;</div>
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        <tr>
          <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-weight: bold;">Item 7.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-weight: bold;">Exemption from Registration Claimed.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: justify; color: rgb(0, 0, 0);">Not applicable.</div>
    <div>&#160;</div>
    <div>
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          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 36pt;">
              <div style="text-align: left;"><font style="font-weight: bold; color: rgb(0, 0, 0);">Item </font><font style="font-weight: bold; color: rgb(0, 0, 0);">8.</font> <br>
              </div>
            </td>
            <td style="vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="font-weight: bold; color: rgb(0, 0, 0);">Exhibits.</font></div>
            </td>
          </tr>

      </table>
    </div>
    <div>&#160;</div>
    <table cellspacing="0" cellpadding="0" id="z0d855d486c314127985eabb83be74fda" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

        <tr>
          <td style="width: 10%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Exhibit</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;"> Number</div>
          </td>
          <td style="width: 1.49%; vertical-align: middle;">&#160;</td>
          <td style="width: 88.51%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">Description</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: center; color: rgb(0, 0, 0);"><a href="https://www.sec.gov/Archives/edgar/data/748592/000101968713003135/ntn_10q-ex0301.htm">3.1</a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 88.51%; vertical-align: bottom; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; color: rgb(0, 0, 0);">Restated Certificate of Incorporation of Brooklyn ImmunoTherapeutics, Inc. (formerly NTN Buzztime, Inc.) (incorporated herein by reference to Exhibit 3.1 to the Quarterly Report on Form
              10-Q filed on August 14, 2013)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);"><a href="https://www.sec.gov/Archives/edgar/data/748592/000149315216010919/ex3-1.htm">3.1(a)</a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top;">&#160;</td>
          <td style="width: 88.51%; vertical-align: bottom;">
            <div style="text-align: justify; color: rgb(0, 0, 0);">Certificate of Amendment to the Restated Certificate of Incorporation of Brooklyn ImmunoTherapeutics, Inc. (formerly NTN Buzztime, Inc.), dated June 16, 2016 (incorporated herein by
              reference to Exhibit 3.1 to the Current Report on Form 8-K filed on June 17, 2016)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: center; color: rgb(0, 0, 0);"><a href="https://www.sec.gov/Archives/edgar/data/748592/000149315217003784/ex3-1.htm">3.1(b)</a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 88.51%; vertical-align: bottom; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; color: rgb(0, 0, 0);">Certificate of Decrease of the Series A convertible preferred stock of Brooklyn ImmunoTherapeutics, Inc. (formerly NTN Buzztime, Inc.), dated April 10, 2017 (incorporated herein by
              reference to Exhibit 3.1 to the Current Report on Form 8-K filed on April 12, 2017)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);"><a href="https://www.sec.gov/Archives/edgar/data/748592/000149315217006434/ex3-1.htm">3.1(c)</a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top;">&#160;</td>
          <td style="width: 88.51%; vertical-align: bottom;">
            <div style="text-align: justify; color: rgb(0, 0, 0);">Certificate of Amendment of Restated Certificate of Incorporation of Brooklyn ImmunoTherapeutics, Inc. (formerly NTN Buzztime, Inc.), dated June 8, 2017 (incorporated herein by reference to
              Exhibit 3.1 to the Current Report on Form 8-K filed on June 9, 2017)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: center; color: rgb(0, 0, 0);"><a href="https://www.sec.gov/Archives/edgar/data/748592/000114036121011095/brhc10022537_ex3-1.htm">3.1(d)</a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 88.51%; vertical-align: bottom; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; color: rgb(0, 0, 0);">Certificate of Amendment of Restated Certificate of Incorporation of Brooklyn ImmunoTherapeutics, Inc. (formerly NTN Buzztime, Inc.), dated March 25, 2021 (incorporated herein by reference
              to Exhibit 3.1 to the Current Report on Form 8-K filed on March 31, 2021)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top;">
            <div style="text-align: center; color: rgb(0, 0, 0);"><a href="https://www.sec.gov/Archives/edgar/data/748592/000114036121011095/brhc10022537_ex3-2.htm">3.1(e)</a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top;">&#160;</td>
          <td style="width: 88.51%; vertical-align: bottom;">
            <div style="text-align: justify; color: rgb(0, 0, 0);">Certificate of Amendment of Restated Certificate of Incorporation of Brooklyn ImmunoTherapeutics, Inc. (formerly NTN Buzztime, Inc.), dated March 25, 2021 (incorporated herein by reference
              to Exhibit 3.2 to the Current Report on Form 8-K filed on March 31, 2021)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: center; color: rgb(0, 0, 0);"><a href="https://www.sec.gov/Archives/edgar/data/748592/000114036121011095/brhc10022537_ex3-3.htm">3.1(f)</a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 88.51%; vertical-align: bottom; background-color: rgb(204, 238, 255);">
            <div style="text-align: justify; color: rgb(0, 0, 0);">Certificate of Amendment of Restated Certificate of Incorporation of Brooklyn ImmunoTherapeutics, Inc. (formerly NTN Buzztime, Inc.), dated March 25, 2021 (incorporated herein by reference
              to Exhibit 3.3 to the Current Report on Form 8-K filed on March 31, 2021)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top;">
            <div style="text-align: center;"><a href="https://www.sec.gov/Archives/edgar/data/748592/000114036121011095/brhc10022537_ex3-4.htm">3.2</a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top;">&#160;</td>
          <td style="width: 88.51%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0);">Amended and Restated Bylaws of Brooklyn ImmunoTherapeutics, Inc. (incorporated herein by reference to Exhibit 3.4 to the Current Report on Form 8-K filed on March 31, 2021)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: center;"><a href="brhc10025341_ex5-1.htm">5.1</a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 88.51%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="color: rgb(0, 0, 0);">Opinion of K&amp;L Gates LLP</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top;">
            <div style="text-align: center;"><a href="brhc10025341_ex23-1.htm">23.1</a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top;">&#160;</td>
          <td style="width: 88.51%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0);">Consent of Baker Tilly US, LLP</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: center;"><a href="brhc10025341_ex23-2.htm">23.2</a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 88.51%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="color: rgb(0, 0, 0);">Consent of Marcum LLP</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top;">
            <div style="text-align: center;"><a href="brhc10025341_ex5-1.htm">23.3</a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top;">&#160;</td>
          <td style="width: 88.51%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0);">Consent of K&amp;L Gates LLP (included in Exhibit 5.1)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: center;"><a href="#SIGNATURE">24.1</a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 88.51%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="color: rgb(0, 0, 0);">Power of Attorney (included on the signature page)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top;">
            <div style="text-align: center;"><a href="https://www.sec.gov/Archives/edgar/data/748592/000114036121011095/brhc10022537_ex10-2.htm">99.1<font style="color: rgb(0, 0, 0);">&#8224;</font></a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top;">&#160;</td>
          <td style="width: 88.51%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0);">Brooklyn ImmunoTherapeutics, Inc. 2020 Stock Incentive Plan (incorporated herein by reference to Exhibit 10.2 to the Current Report on Form 8-K filed on March 31, 2021)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: center;"><a href="https://www.sec.gov/Archives/edgar/data/748592/000114036121012036/brhc10022864_ex10-1.htm">99.2<font style="color: rgb(0, 0, 0);">&#8224;</font></a></div>
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          <td style="width: 1.49%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
          <td style="width: 88.51%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="color: rgb(0, 0, 0);">Executive Employment Agreement, dated as of April 1, 2021 and effective as of April 16, 2021, between Brooklyn ImmunoTherapeutics, Inc. and Howard J. Federoff (incorporated herein by reference to Exhibit 10.1
              to the Current Report on Form 8-K filed on April 7, 2021)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 10%; vertical-align: top;">
            <div style="text-align: center;"><a href="https://www.sec.gov/Archives/edgar/data/748592/000114036121018871/brhc10025183_ex10-3.htm">99.3<font style="color: rgb(0, 0, 0);">&#8224;</font></a></div>
          </td>
          <td style="width: 1.49%; vertical-align: top;">&#160;</td>
          <td style="width: 88.51%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0);">Brooklyn ImmunoTherapeutics, Inc. 2021 Inducement Stock Incentive Plan (incorporated herein by reference to Exhibit 10.3 to the Current Report on Form 8-K filed on May 26, 2021)</div>
          </td>
        </tr>

    </table>
    <div><br>
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          <td style="width: 18pt; vertical-align: top; color: rgb(0, 0, 0);">&#8224;</td>
          <td style="width: auto; vertical-align: top;">
            <div style="color: rgb(0, 0, 0);">Management contract or compensatory plan.</div>
          </td>
        </tr>

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    <div><font style="color: rgb(0, 0, 0);">1.</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(0, 0, 0);">The Company hereby undertakes:</font></div>
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            <div style="color: rgb(0, 0, 0);">to file, during any period in which offers or sales are being made, a post-effective amendment to this registration statement:</div>
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            <div style="color: rgb(0, 0, 0);">to include any prospectus required by Section 10(a)(3) of the Securities Act;</div>
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            <div style="color: rgb(0, 0, 0);">to include any material information with respect to the plan of distribution not previously disclosed in the registration statement or any material change to such information in the registration statement;</div>
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    <div style="text-align: justify; margin-left: 36pt; color: rgb(0, 0, 0);"><font style="font-style: italic;">provided, however, </font>that paragraphs (a)(i) and (a)(ii) do not apply if the registration statement is on Form S&#8209;8 and the information
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            <div style="color: rgb(0, 0, 0);">that, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered herein, and
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            <div style="color: rgb(0, 0, 0);">to remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.</div>
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            <div style="color: rgb(0, 0, 0);">The Company hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Company&#8217;s annual report pursuant to Section 13(a) or 15(d) of the Exchange Act (and,
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            <div style="color: rgb(0, 0, 0);">Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Company pursuant to the foregoing provisions, or otherwise, the
              Company has been advised that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for
              indemnification against such liabilities (other than the payment by the Company of expenses incurred or paid by a director, officer or controlling person of the Company in the successful defense of any action, suit or proceeding) is asserted
              by such director, officer or controlling person in connection with the securities being registered, the Company will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate
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    <div style="text-align: justify; color: rgb(0, 0, 0);">Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has
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          <td style="width: 50%; vertical-align: top;" rowspan="1">&#160;</td>
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    <div style="text-align: justify; color: rgb(0, 0, 0);">Each person whose signature appears below hereby constitutes and appoints Howard J. Federoff and Ronald Guido, and each of them, as his or her true and lawful attorney-in-fact and agent with full
      power of substitution, for him or her in any and all capacities, to sign any and all amendments to this registration statement (including post-effective amendments or any abbreviated registration statement), and to file the same, with all exhibits
      thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite and necessary to be done
      in connection therewith, as fully for all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorney-in-fact and agent, or his substitute, may lawfully do or cause to be done by virtue
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    <div style="text-align: justify; color: rgb(0, 0, 0);">Pursuant to the requirements of the Securities Act of 1933, this registration statement has been signed below by the following persons on behalf of the registrant in the capacities and on the dates
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          <td style="width: 46.32%; vertical-align: bottom;">&#160;</td>
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          <td style="width: 0.54%; vertical-align: bottom;">&#160;</td>
          <td style="width: 16.68%; vertical-align: bottom;">&#160;</td>
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<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>brhc10025341_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
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      <div style="text-align: right; color: rgb(0, 0, 0); font-variant: normal; font-weight: bold;">Exhibit 5.1</div>
      <div>&#160;</div>
      <div style="text-align: center; color: rgb(0, 0, 0);">
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          <div style="text-align: left;">&#160; <br>
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        <div style="text-align: justify;">June 3, 2021</div>
        <div>&#160;</div>
        <div style="text-align: justify; text-indent: -36pt; margin-left: 36pt; font-variant: small-caps;"><a name="lblRe"></a>Brooklyn ImmunoTherapeutics, Inc.</div>
        <div style="text-align: justify;"><a name="Salutation"></a>140 58<sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">th</sup> Street, Building A, Suite 2100</div>
        <div style="text-align: justify;">Brooklyn, New York 11220</div>
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        <div style="text-align: justify;">Ladies and Gentlemen:</div>
        <div>&#160;</div>
        <div style="text-align: justify;">We are counsel to Brooklyn ImmunoTherapeutics, Inc., a Delaware corporation (the &#8220;<font style="font-style: italic;">Company</font>&#8221;), and we have acted as counsel to the Company in connection with the preparation
          of the Registration Statement on Form S-8 (the &#8220;<font style="font-style: italic;">Registration Statement</font>&#8221;) to be filed by the Company with the Securities and Exchange Commission (the &#8220;<font style="font-style: italic;">SEC</font>&#8221;) for the
          registration under the Securities Act of 1933, as amended (the &#8220;<font style="font-style: italic;">Securities Act</font>&#8221;), of <font style="color: rgb(0, 0, 0);">8,093,972</font> shares (the &#8220;<font style="font-style: italic;">Shares</font>&#8221;) of
          the Company&#8217;s common stock, $0.005 par value per share (&#8220;<font style="font-style: italic;">Common Stock</font>&#8221;), consisting of (a) 3,368,804 shares authorized for issuance under the Company&#8217;s 2020 Stock Incentive Plan (the &#8220;<font style="font-style: italic;">Incentive Plan</font>&#8221;), (b) 1,500,000 shares authorized for issuance under the Company&#8217;s 2021 Inducement Stock Incentive Plan (the &#8220;<font style="font-style: italic;">Inducement Plan</font>&#8221;), and (c) 3,225,168
          shares authorized for issuance under the Company&#8217;s Executive Employment Agreement dated as of April 1, 2021 with Howard J. Federoff (the &#8220;<font style="font-style: italic;">Employment Agreement</font>&#8221;).</div>
        <div>&#160;</div>
        <div style="text-align: justify;">This opinion letter is being delivered in accordance with the requirements of Item 601(b)(5) of Regulation S&#8209;K under the Securities Act.</div>
        <div>&#160;</div>
        <div style="text-align: justify;">You have requested our opinion as to the matters set forth below in connection with the Registration Statement. For purposes of rendering that opinion, we have examined and relied on (i) a signed copy of the
          Registration Statement, (ii) the Incentive Plan, (iii) the Inducement Plan, (iv) a signed copy of the Employment Agreement, (v) the Restated Certificate of Incorporation of the Company, as amended, and the Amended and Restated Bylaws of the
          Company, each as currently in effect, (vi) the Company&#8217;s stock ledger, and (v) the corporate actions of the Company that provide for the issuance of the Shares, <font style="color: rgb(0, 0, 0);">and we have made such other investigation as we
            have deemed appropriate. </font>We have also examined and relied upon certificates of public officials and, as to certain matters of fact that are material to our opinion, we have also relied on a certificate of an officer of the Company.</div>
        <div>&#160;</div>
        <div style="text-align: justify;">
          <div style="color: #000000; font-family: 'Times New Roman', Times, serif;">For the purposes of this opinion letter, we have made assumptions that are customary in opinion letters of this kind, including the
            accuracy and completeness of each document furnished to us, the authenticity of all documents submitted to us as originals, the conformity to original documents of all documents submitted to us as copies and the authenticity of all such
            originals, the legal competence of all signatories to such documents, and the genuineness of all signatures. In rendering our opinion below, we also have assumed that (a) the Company will have sufficient authorized and unissued or treasury
            shares of Common Stock at the time of issuance of the Shares, (b) all Shares will be evidenced by certificates or the Company&#8217;s Board of Directors will have adopted a resolution providing that all shares of Common Stock shall be uncertificated
            in accordance with Section 158 of the Delaware General Corporation Law (the &#8220;<font style="font-style: italic;">DGCL</font>&#8221;), prior to their issuance, (c) the issuance of the Shares
            will be duly noted in the Company&#8217;s stock ledger upon issuance, and (d) the Company will receive consideration for each of the Shares at least equal to the par value of such share of Common Stock and in the amount required by the Incentive
            Plan, the Inducement Plan or the Employment Agreement, as applicable. We have not verified any of those assumptions.</div>
        </div>
        <div style="text-align: justify;"> <br>
        </div>
        <div id="DSPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
          <div style="width: 100%;" id="DSPFPageFooter">
            <div>
              <div style="text-align: left; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">K&amp;L GATES LLP</div>
              <div style="text-align: left; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">STATE STREET FINANCIAL CENTER&#160;&#160; ONE LINCOLN STREET&#160;&#160; BOSTON&#160;&#160; MA 02111</div>
              <div style="text-align: left; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">T +1 617 261 3100&#160; F +1 617 261 3175&#160; klgates.com</div>
            </div>
          </div>
          <div id="DSPFPageBreak" style="page-break-after:always;">
            <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
          <div style="width: 100%;" id="DSPFPageHeader">
            <div>
              <div style="text-align: left; font-family: 'Times New Roman', Times, serif;">K&amp;L Gates LLP</div>
              <div style="text-align: left; font-family: 'Times New Roman', Times, serif;">June 3, 2021</div>
              <div style="text-align: left; font-family: 'Times New Roman', Times, serif;">Page <font id="DSPFPageNumber">2</font></div>
            </div>
          </div>
        </div>
        <div style="text-align: justify;">Our opinion is limited to the DGCL.&#160; The foregoing opinion is rendered as of the date of this letter. We assume no obligation to update or supplement such opinion in order to reflect any changes of law or fact that
          may occur.</div>
        <div>&#160;</div>
        <div style="text-align: justify;">Based upon and subject to the foregoing and the additional qualifications and other matters set forth below, we are of the opinion that the Shares have been duly and validly authorized and reserved for issuance and
          that the Shares, when issued in accordance with the terms of the Incentive Plan, the Inducement Plan or the Employment Agreement, as applicable, will be validly issued, fully paid and nonassessable.</div>
        <div>&#160;</div>
        <div style="text-align: justify;">Our opinion is subject to the effects of general principles of equity, whether considered in a proceeding at law or equity.</div>
        <div>&#160;</div>
        <div style="text-align: justify; color: rgb(0, 0, 0);">We are furnishing this opinion letter to you solely in connection with the Registration Statement.&#160; You may not rely on this opinion letter in any other connection, and it may not be furnished
          to or relied upon by any other person for any purpose, without our specific prior written consent.</div>
        <div>&#160;</div>
        <div style="text-align: justify;">We hereby consent to the filing of this opinion letter with the SEC as Exhibit 5.1 to the Registration Statement in accordance with the requirements of Item 6.01(b)(5) of Regulation S-K under the Securities Act and
          to the reference to our firm wherever appearing in the Registration Statement. In giving our consent we do not thereby admit that we are in the category of persons whose consent is required under Section 7 of the Securities Act or the rules and
          regulations thereunder.</div>
        <div>&#160;</div>
        <table cellspacing="0" cellpadding="0" border="0" id="z73858536b0d54f1eaa29df4d8f1c1fab" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

            <tr>
              <td style="width: 100%; vertical-align: top;">
                <div style="text-align: justify;"><a name="Closing"></a>Very truly yours,</div>
              </td>
            </tr>
            <tr>
              <td style="width: 100%; vertical-align: top;">&#160;</td>
            </tr>
            <tr>
              <td style="width: 100%; vertical-align: top;">
                <div style="text-align: justify;">/s/ K&amp;L Gates LLP</div>
              </td>
            </tr>
            <tr>
              <td style="width: 100%; vertical-align: top;">&#160;</td>
            </tr>
            <tr>
              <td style="width: 100%; vertical-align: top;">
                <div style="text-align: justify; font-variant: small-caps;">K&amp;L Gates LLP</div>
              </td>
            </tr>

        </table>
        <div style="text-align: justify;"><a name="Initials"></a><a name="Enclosure"></a><a name="CC"></a><a name="bcc"></a><br>
        </div>
        <div>&#160;</div>
      </div>
      <div style="text-align: center; color: rgb(0, 0, 0);">
        <hr noshade="noshade" align="center" style="height: 2px; color: rgb(0, 0, 0); background-color: rgb(0, 0, 0); border: medium none;"> </div>
    </div>
  </div>
</body>
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</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>brhc10025341_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
<html>
  <head>
    <title></title>
    <!-- Licensed to: Broadridge
         Document created using EDGARfilings PROfile 7.5.0.0
         Copyright 1995 - 2021 Broadridge -->
  </head>
<body bgcolor="#ffffff" style="font-family: 'Times New Roman'; font-size: 10pt; text-align: left; color: #000000;">
  <div>
    <hr noshade="noshade" align="center" style="height: 4px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;">
    <div>
      <div style="text-align: right; color: rgb(0, 0, 0); font-variant: small-caps; font-weight: bold;">Exhibit 23.1</div>
      <div>&#160;</div>
      <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;">CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM</div>
      <div>&#160;</div>
      <div style="text-align: justify; color: rgb(0, 0, 0);">We consent to the incorporation by reference in this Registration Statement on Form S-8 of Brooklyn ImmunoTherapeutics, Inc. (formerly
        known as NTN Buzztime, Inc.) of our report dated March 11, 2021, relating to the consolidated financial statements of NTN Buzztime, Inc. appearing in the Annual Report on Form 10-K of NTN Buzztime, Inc. for the year ended December 31, 2020 (which
        report expresses an unqualified opinion and includes an explanatory paragraph relating to the Company&#8217;s ability to continue as a going concern).</div>
      <div><br>
      </div>
      <div style="color: rgb(0, 0, 0);">/s/ BAKER TILLY US, LLP</div>
      <div style="color: rgb(0, 0, 0);">San Diego, California</div>
      <div style="color: rgb(0, 0, 0);">June 3, 2021</div>
      <div style="color: rgb(0, 0, 0);"> <br>
      </div>
      <div style="color: rgb(0, 0, 0);"> <br>
      </div>
      <div style="color: rgb(0, 0, 0);">
        <hr noshade="noshade" align="center" style="height: 2px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;"> </div>
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  </div>
</body>
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</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>4
<FILENAME>brhc10025341_ex23-2.htm
<DESCRIPTION>EXHIBIT 23.2
<TEXT>
<html>
  <head>
    <title></title>
    <!-- Licensed to: Broadridge
         Document created using EDGARfilings PROfile 7.5.0.0
         Copyright 1995 - 2021 Broadridge -->
  </head>
<body bgcolor="#ffffff" style="font-family: 'Times New Roman'; font-size: 10pt; text-align: left; color: #000000;">
  <div>
    <hr noshade="noshade" align="center" style="height: 4px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;">
    <div>
      <div style="text-align: right; color: rgb(0, 0, 0); font-variant: small-caps; font-weight: bold;">Exhibit 23.2</div>
      <div>&#160;</div>
      <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold;"><u>INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM&#8217;S CONSENT</u></div>
      <div>&#160;</div>
      <div>
        <div style="text-align: justify; color: rgb(0, 0, 0);">We consent to the incorporation by reference in this Registration Statement of Brooklyn ImmunoTherapeutics, Inc. on Form S-8 of our
          report dated April 30, 2021, with respect to our audits of the financial statements of Brooklyn ImmunoTherapeutics, LLC as of December 31, 2020 and 2019 and for each of the two years in the period ended December 31, 2020 appearing in Amendment
          No. 1 to Form 8-K/A of Brooklyn ImmunoTherapeutics, Inc. dated April 30, 2021.</div>
        <div>&#160;</div>
      </div>
      <div>
        <div style="color: rgb(0, 0, 0);">/s/ Marcum <font style="font-variant: small-caps;">llp</font></div>
        <div><br>
        </div>
      </div>
      <div>
        <div style="color: rgb(0, 0, 0);">Marcum <font style="font-variant: small-caps;">llp</font></div>
        <div style="color: rgb(0, 0, 0);">New York, NY</div>
        <div style="color: rgb(0, 0, 0);">June 3, 2021</div>
        <div><br>
        </div>
        <div><br>
        </div>
        <div>
          <hr noshade="noshade" align="center" style="height: 2px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;"></div>
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</TEXT>
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