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v3.23.1

Related Party Transactions (Details) |  |  |  |  |  | 1 Months Ended | 12 Months Ended
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Dec. 02, 2022 USD ($) | Nov. 23, 2022 $ / shares shares | Oct. 08, 2022 USD ($) | Jul. 12, 2022 USD ($) $ / shares | Mar. 06, 2022 $ / shares shares | Oct. 31, 2022 USD ($) | Sep. 30, 2022 USD ($) | Dec. 31, 2022 USD ($) Installment | Dec. 31, 2021 USD ($)
Related Party Transaction [Abstract] |  |  |  |  |  |  |  |  |
Research and development expense |  |  |  |  |  |  |  | $ 10,392,000 | $ 12,705,000
Common Warrants [Member] |  |  |  |  |  |  |  |  |
Q4-22 PIPE Transaction [Abstract] |  |  |  |  |  |  |  |  |
Warrant exercise price (in dollars per share) | $ / shares |  |  |  |  | $ 38.2 |  |  |  |
Warrant exercisable term |  |  |  |  |  |  |  | 6 months |
Warrant expiration term |  |  |  |  |  |  |  | 5 years 6 months |
Pre-funded Warrants [Member] |  |  |  |  |  |  |  |  |
Q4-22 PIPE Transaction [Abstract] |  |  |  |  |  |  |  |  |
Warrant exercise price (in dollars per share) | $ / shares |  | $ 0.125 |  |  |  |  |  |  |
PIPE Investor [Member] |  |  |  |  |  |  |  |  |
Q4-22 PIPE Transaction [Abstract] |  |  |  |  |  |  |  |  |
Private placement (in shares) | shares |  | 2,185,000 |  |  | 343,000 |  |  |  |
Number of common stock (in shares) | shares |  |  |  |  | 1 |  |  |  |
Unit price (in dollars per share) | $ / shares |  | $ 3.53 |  |  |  |  |  |  |
Warrant exercise price (in dollars per share) | $ / shares |  |  |  |  | $ 0.1 |  |  |  |
Proceeds from issuance of warrants to purchase of common stock | $ 7,700,000 |  |  |  |  |  |  |  |
Warrant exercisable term |  |  |  |  | 6 months |  |  |  |
Warrant expiration term |  |  |  |  | 5 years 6 months |  |  |  |
PIPE Investor [Member] | Common Warrants [Member] |  |  |  |  |  |  |  |  |
Q4-22 PIPE Transaction [Abstract] |  |  |  |  |  |  |  |  |
Private placement (in shares) | shares |  |  |  |  | 343,000 |  |  |  |
Number of common stock (in shares) | shares |  | 1 |  |  | 1 |  |  |  |
Warrant exercise price (in dollars per share) | $ / shares |  | $ 3.28 |  |  |  |  |  |  |
Warrant exercisable term |  |  |  |  |  |  |  | 6 months |
Warrant expiration term |  |  |  |  |  |  |  | 5 years 6 months |
PIPE Investor [Member] | Pre-funded Warrants [Member] |  |  |  |  |  |  |  |  |
Q4-22 PIPE Transaction [Abstract] |  |  |  |  |  |  |  |  |
Private placement (in shares) | shares |  |  |  |  | 68,000 |  |  |  |
Number of common stock (in shares) | shares |  | 2 |  |  | 1 |  |  |  |
Warrant exercise price (in dollars per share) | $ / shares |  |  |  | $ 0.1 |  |  |  |  |
Proceeds from issuance of warrants to purchase of common stock |  |  |  | $ 7,000 |  |  |  |  |
Factor Bioscience Inc. [Member] |  |  |  |  |  |  |  |  |
Related Party Transaction [Abstract] |  |  |  |  |  |  |  |  |
Master services agreement, initial fees payable |  |  |  |  |  |  | $ 5,000,000 |  |
Number of monthly installments for fees payable | Installment |  |  |  |  |  |  |  | 12 |
Monthly installment fees amount |  |  |  |  |  |  | 400,000 |  |
Initial license fees obligation |  |  |  |  |  |  | 3,500,000 |  |
Monthly master services agreement fees payable initial 12-month |  |  |  |  |  |  | 400,000 |  |
Deposit paid to be applied to last month of first work order |  |  |  |  |  |  | 400,000 |  |
Notice period for first termination of contract |  |  |  |  |  |  |  | 120 days |
Notice period for superseding termination provisions |  |  |  |  |  |  |  | 30 days |
Agreed waive payment |  |  |  |  |  |  | 3,500,000 |  |
Research and development expense |  |  |  |  |  |  | $ 3,500,000 |  |
Remaining license fee obligation |  |  |  |  |  |  |  | $ 3,000,000 |
Reimburse costs incurred or paid |  |  |  |  |  | $ 100,000 |  |  |
Exacis Biotherapeutics, Inc. [Member] |  |  |  |  |  |  |  |  |
Exacis Option Agreement [Abstract] |  |  |  |  |  |  |  |  |
Payment of option fee |  |  | $ 300,000 |  |  |  |  |  |

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