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Related Party Transactions (Details)						1 Months Ended		12 Months Ended
	Dec. 02, 2022 USD ($)	Nov. 23, 2022 $ / shares shares	Oct. 08, 2022 USD ($)	Jul. 12, 2022 USD ($) $ / shares	Mar. 06, 2022 $ / shares shares	Oct. 31, 2022 USD ($)	Sep. 30, 2022 USD ($)	Dec. 31, 2022 USD ($) Installment	Dec. 31, 2021 USD ($)
Related Party Transaction [Abstract]
Research and development expense								$ 10,392,000	$ 12,705,000
Common Warrants [Member]
Q4-22 PIPE Transaction [Abstract]
Warrant exercise price (in dollars per share) | $ / shares					$ 38.2
Warrant exercisable term								6 months
Warrant expiration term								5 years 6 months
Pre-funded Warrants [Member]
Q4-22 PIPE Transaction [Abstract]
Warrant exercise price (in dollars per share) | $ / shares		$ 0.125
PIPE Investor [Member]
Q4-22 PIPE Transaction [Abstract]
Private placement (in shares) | shares		2,185,000			343,000
Number of common stock (in shares) | shares					1
Unit price (in dollars per share) | $ / shares		$ 3.53
Warrant exercise price (in dollars per share) | $ / shares					$ 0.1
Proceeds from issuance of warrants to purchase of common stock	$ 7,700,000
Warrant exercisable term					6 months
Warrant expiration term					5 years 6 months
PIPE Investor [Member] | Common Warrants [Member]
Q4-22 PIPE Transaction [Abstract]
Private placement (in shares) | shares					343,000
Number of common stock (in shares) | shares		1			1
Warrant exercise price (in dollars per share) | $ / shares		$ 3.28
Warrant exercisable term								6 months
Warrant expiration term								5 years 6 months
PIPE Investor [Member] | Pre-funded Warrants [Member]
Q4-22 PIPE Transaction [Abstract]
Private placement (in shares) | shares					68,000
Number of common stock (in shares) | shares		2			1
Warrant exercise price (in dollars per share) | $ / shares				$ 0.1
Proceeds from issuance of warrants to purchase of common stock				$ 7,000
Factor Bioscience Inc. [Member]
Related Party Transaction [Abstract]
Master services agreement, initial fees payable							$ 5,000,000
Number of monthly installments for fees payable | Installment								12
Monthly installment fees amount							400,000
Initial license fees obligation							3,500,000
Monthly master services agreement fees payable initial 12-month							400,000
Deposit paid to be applied to last month of first work order							400,000
Notice period for first termination of contract								120 days
Notice period for superseding termination provisions								30 days
Agreed waive payment							3,500,000
Research and development expense							$ 3,500,000
Remaining license fee obligation								$ 3,000,000
Reimburse costs incurred or paid						$ 100,000
Exacis Biotherapeutics, Inc. [Member]
Exacis Option Agreement [Abstract]
Payment of option fee			$ 300,000

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