<SEC-DOCUMENT>0001104659-21-050962-index.html : 20210416
<SEC-HEADER>0001104659-21-050962.hdr.sgml : 20210416
<ACCEPTANCE-DATETIME>20210415202133
ACCESSION NUMBER:		0001104659-21-050962
CONFORMED SUBMISSION TYPE:	S-1/A
PUBLIC DOCUMENT COUNT:		23
FILED AS OF DATE:		20210416
DATE AS OF CHANGE:		20210415

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Transcode Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001829635
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				811065054
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-253599
		FILM NUMBER:		21829868

	BUSINESS ADDRESS:	
		STREET 1:		6 LIBERTY SQUARE
		STREET 2:		#2382
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02109
		BUSINESS PHONE:		857-301-6857

	MAIL ADDRESS:	
		STREET 1:		6 LIBERTY SQUARE
		STREET 2:		#2382
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02109
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-1/A
<SEQUENCE>1
<FILENAME>tm2038085-13_s1a.htm
<DESCRIPTION>S-1/A
<TEXT>
Document 1 - file: tm2038085-13_s1a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>2
<FILENAME>tm2038085d15_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
Document 2 - file: tm2038085d15_ex23-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>lg_transcode-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: lg_transcode-4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>tm2038085d5-cover_page14clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: tm2038085d5-cover_page14clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>tm2038085d5-cover_page24clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: tm2038085d5-cover_page24clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>tm203808510-fc_modular4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: tm203808510-fc_modular4c.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>tm2038085d2-fc_overview4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: tm2038085d2-fc_overview4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>tm2038085d5-tbl_pipe4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: tm2038085d5-tbl_pipe4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>tm2038085d5-ph_select4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: tm2038085d5-ph_select4c.jpg

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<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>tm2038085d2-ph_target4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: tm2038085d2-ph_target4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>tm2038085d2-ph_axialmr4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: tm2038085d2-ph_axialmr4c.jpg

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<SEQUENCE>12
<FILENAME>tm2038085d2-fc_position4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 12 - file: tm2038085d2-fc_position4c.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>13
<FILENAME>tm2038085d2-fc_key4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 13 - file: tm2038085d2-fc_key4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>14
<FILENAME>tm2038085d2-ph_inhibit4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 14 - file: tm2038085d2-ph_inhibit4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>15
<FILENAME>tm2038085d2-fc_effect4c.jpg
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<TEXT>
Document 15 - file: tm2038085d2-fc_effect4c.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>16
<FILENAME>tm2038085d10-bc_effect4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 16 - file: tm2038085d10-bc_effect4clr.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>17
<FILENAME>tm2038085d2-fc_study4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 17 - file: tm2038085d2-fc_study4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>18
<FILENAME>tm2038085d5-lc_preclin4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 18 - file: tm2038085d5-lc_preclin4clr.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>19
<FILENAME>tm2038085d5-bc_preclin4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 19 - file: tm2038085d5-bc_preclin4clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>20
<FILENAME>tm2038085d5-fc_clinical4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 20 - file: tm2038085d5-fc_clinical4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>21
<FILENAME>tm2038085d5-ph_mechan4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 21 - file: tm2038085d5-ph_mechan4clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>22
<FILENAME>tm2038085d7-lc_figure144c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 22 - file: tm2038085d7-lc_figure144c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>23
<FILENAME>tm2038085d2-lc_figure154clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 23 - file: tm2038085d2-lc_figure154clr.jpg

</DOCUMENT>
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