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Summary of significant accounting policies - Net loss per share (Details) - shares | 12 Months Ended
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Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Potentially dilutive securities that have been excluded from the calculation of diluted net loss per share |  |  |
Total shares of common stock equivalents | 3,771,459 | 3,499,934 | 14,405,301
Series A convertible preferred stock |  |  |
Potentially dilutive securities that have been excluded from the calculation of diluted net loss per share |  |  |
Total shares of common stock equivalents |  |  | 612,446
Series B convertible preferred stock |  |  |
Potentially dilutive securities that have been excluded from the calculation of diluted net loss per share |  |  |
Total shares of common stock equivalents |  |  | 7,235,969
Series C convertible preferred stock |  |  |
Potentially dilutive securities that have been excluded from the calculation of diluted net loss per share |  |  |
Total shares of common stock equivalents |  |  | 4,712,698
Options to purchase common stock |  |  |
Potentially dilutive securities that have been excluded from the calculation of diluted net loss per share |  |  |
Total shares of common stock equivalents | 3,771,459 | 3,499,934 | 1,844,188

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- Definition Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 + Details
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