<SEC-DOCUMENT>0001558370-22-009490-index.html : 20220527
<SEC-HEADER>0001558370-22-009490.hdr.sgml : 20220527
<ACCEPTANCE-DATETIME>20220527170017
ACCESSION NUMBER:		0001558370-22-009490
CONFORMED SUBMISSION TYPE:	PRE 14A
PUBLIC DOCUMENT COUNT:		19
CONFORMED PERIOD OF REPORT:	20220728
FILED AS OF DATE:		20220527
DATE AS OF CHANGE:		20220527

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Aprea Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001781983
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		PRE 14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39069
		FILM NUMBER:		22978664

	BUSINESS ADDRESS:	
		STREET 1:		535 BOYLSTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
		BUSINESS PHONE:		6095104718

	MAIL ADDRESS:	
		STREET 1:		535 BOYLSTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
</SEC-HEADER>
<DOCUMENT>
<TYPE>PRE 14A
<SEQUENCE>1
<FILENAME>apre-20220728xpre14a.htm
<DESCRIPTION>PRE 14A
<TEXT>
Document 1 - file: apre-20220728xpre14a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>apre-20220728xpre14a008.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: apre-20220728xpre14a008.jpg

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<DOCUMENT>
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<SEQUENCE>3
<FILENAME>apre-20220728xpre14a013.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: apre-20220728xpre14a013.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>apre-20220728xpre14a011.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: apre-20220728xpre14a011.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>apre-20220728xpre14a012.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: apre-20220728xpre14a012.jpg

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<DOCUMENT>
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<SEQUENCE>6
<FILENAME>apre-20220728xpre14a001.jpg
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<TEXT>
Document 6 - file: apre-20220728xpre14a001.jpg

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<DOCUMENT>
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<FILENAME>apre-20220728xpre14a026.jpg
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<TEXT>
Document 7 - file: apre-20220728xpre14a026.jpg

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<DOCUMENT>
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<SEQUENCE>8
<FILENAME>apre-20220728xpre14a009.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: apre-20220728xpre14a009.jpg

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<DOCUMENT>
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Document 9 - file: apre-20220728xpre14a007.jpg

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Document 10 - file: apre-20220728xpre14a016.jpg

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<TEXT>
Document 11 - file: apre-20220728xpre14a025.jpg

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<SEQUENCE>12
<FILENAME>apre-20220728xpre14a010.jpg
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<TEXT>
Document 12 - file: apre-20220728xpre14a010.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>13
<FILENAME>apre-20220728xpre14a006.jpg
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<TEXT>
Document 13 - file: apre-20220728xpre14a006.jpg

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Document 14 - file: apre-20220728xpre14a018.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>15
<FILENAME>apre-20220728xpre14a004.jpg
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<TEXT>
Document 15 - file: apre-20220728xpre14a004.jpg

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<SEQUENCE>16
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Document 16 - file: apre-20220728xpre14a014.jpg

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<SEQUENCE>17
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<TEXT>
Document 17 - file: apre-20220728xpre14a015.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>18
<FILENAME>apre-20220728xpre14a005.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 18 - file: apre-20220728xpre14a005.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>19
<FILENAME>apre-20220728xpre14a017.jpg
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<TEXT>
Document 19 - file: apre-20220728xpre14a017.jpg

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