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v3.23.1

Consolidated Statements of Cash Flows - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Cash flows from operating activities: |  |  |
Net loss | $ (112,662,027) | $ (37,127,303) | $ (53,478,812)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Acquired in-process research and development | 72,523,293 |  |
Depreciation and amortization | 4,403 | 12,829 | 28,834
Stockbased compensation | 16,981,266 | 7,813,743 | 4,983,023
Amortization of right of use lease asset | 182,042 | 258,848 | 200,776
Foreign currency (gain) loss | (281,534) | (317,402) | 890,252
Changes in operating assets and liabilities: |  |  |
Prepaid expenses and other current assets | 2,190,086 | (109,338) | (472,402)
Accounts payable | (858,513) | (2,730,587) | 2,326,767
Accrued expenses and other liabilities | (2,903,450) | (5,218,241) | 3,928,684
Lease liability | (186,702) | (268,728) | (209,794)
Net cash used in operating activities | (25,011,136) | (37,686,179) | (41,802,672)
Cash flows from investing activities: |  |  |
Purchases of property and equipment |  |  | (25,709)
Net cash used in investing activities |  |  | (25,709)
Cash flows from financing activities: |  |  |
Proceeds from the exercise of stock options |  | 208,367 | 150,949
Proceeds from at-the-market sales of common stock, net | 682,973 | 1,538,645 |
Net cash provided by financing activities | 682,973 | 1,747,012 | 150,949
Decrease in cash and cash equivalents | (24,328,163) | (35,939,167) | (41,677,432)
Effect of exchange rate changes on cash | 38,758 | (2,467) | 606,249
Cash and cash equivalents-beginning of year | 53,076,052 | 89,017,686 | 130,088,869
Cash and cash equivalents-end of period | 28,786,647 | 53,076,052 | $ 89,017,686
Non-cash investing and financing activities: |  |  |
Operating lease liabilities arising from obtaining right-of-use assets | 123,786 | $ 124,043 |
Issuance of convertible preferred stock and common stock in connection with acquisition | $ 70,107,167 |  |

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