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v3.23.1

Stockholders' equity (Details) |  |  | 12 Months Ended |
--- | --- | --- | --- | ---
Sep. 02, 2022 USD ($) | May 16, 2022 $ / shares shares | Dec. 31, 2022 USD ($) Vote $ / shares shares | Dec. 31, 2021 USD ($) $ / shares shares | Dec. 31, 2020 shares | Nov. 12, 2020 USD ($)
Common stock |  |  |  |  |  |
Stock, shares authorized |  |  | 440,000,000 |  |  |
Common stock, shares authorized |  |  | 400,000,000 | 400,000,000 |  |
Common stock, par value (in dollars per share) | $ / shares |  |  | $ 0.001 | $ 0.001 |  |
Preferred stock, shares authorized |  |  | 40,000,000 |  |  |
Preferred stock, par value (in dollars per share) | $ / shares |  |  | $ 0.001 |  |  |
Proceeds from at-the-market sales of common stock, net | $ |  |  | $ 682,973 | $ 1,538,645 |  |
Number of voting rights per common share | Vote |  |  | 1 |  |  |
Shelf Registration Statement |  |  |  |  |  |
Maximum amount to be issued under universal shelf registration statement | $ |  |  |  |  |  | $ 350,000,000.0
Common Stock |  |  |  |  |  |
Common stock |  |  |  |  |  |
Conversion of preferred stock into common stock (in shares) |  |  | 1,446,701 |  |  |
Series A Convertible Preferred Stock |  |  |  |  |  |
Common stock |  |  |  |  |  |
Conversion of preferred stock into common stock (in shares) |  |  | 2,893,403 |  |  |
Number of shares remained to be converted into common stock |  |  | 56,227 |  |  |
Atrin Pharmaceuticals, Inc | Common Stock |  |  |  |  |  |
Common stock |  |  |  |  |  |
Common stock, par value (in dollars per share) | $ / shares |  | $ 0.001 |  |  |  |
Issuance of stock upon acquisition of Atrin (in shares) |  | 55,869 |  |  |  |
Atrin Pharmaceuticals, Inc | Series A Convertible Preferred Stock |  |  |  |  |  |
Common stock |  |  |  |  |  |
Issuance of stock upon acquisition of Atrin (in shares) |  | 2,949,630 |  |  |  |
Preferred stock conversion ratio |  | 10 |  |  |  |
ATM offering |  |  |  |  |  |
Common stock |  |  |  |  |  |
Number of shares issued |  |  | 38,481 | 18,338 | 0 |
Commission payable as a percentage of gross proceeds from sale of common stock under ATM offering | 3.00% |  |  |  |  |
Proceeds from at-the-market sales of common stock, net | $ |  |  | $ 700,000 | $ 1,500,000 |  |
Shelf Registration Statement |  |  |  |  |  |
Maximum amount to be issued under at-the-market offering program | $ | $ 14,744,728 |  |  |  |  |

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