<?xml version="1.0" encoding="utf-8"?>
<xbrl
  xmlns="http://www.xbrl.org/2003/instance"
  xmlns:apre="http://aprea.com/20240930"
  xmlns:dei="http://xbrl.sec.gov/dei/2024"
  xmlns:ecd="http://xbrl.sec.gov/ecd/2024"
  xmlns:iso4217="http://www.xbrl.org/2003/iso4217"
  xmlns:link="http://www.xbrl.org/2003/linkbase"
  xmlns:srt="http://fasb.org/srt/2024"
  xmlns:us-gaap="http://fasb.org/us-gaap/2024"
  xmlns:xbrldi="http://xbrl.org/2006/xbrldi"
  xmlns:xlink="http://www.w3.org/1999/xlink"
  xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <link:schemaRef xlink:href="apre-20240930.xsd" xlink:type="simple"/>
    <context id="As_Of_9_30_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_8visgBbaHUi1WL8smvF9Lg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">apre:ConvertiblePreferredStockSeriesaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:PreferredStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-09-30</instant>
        </period>
    </context>
    <context id="As_Of_9_30_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_vRazHx54bUee8EgCl6bZxg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">apre:ConvertiblePreferredStockSeriesaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-09-30</instant>
        </period>
    </context>
    <context id="As_Of_6_30_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_MQGoU-f5K02GZ9PlM-yOkA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">apre:ConvertiblePreferredStockSeriesaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:PreferredStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-06-30</instant>
        </period>
    </context>
    <context id="As_Of_3_31_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_liwNe_OrZkuTHNDpnZcmag">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">apre:ConvertiblePreferredStockSeriesaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:PreferredStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-03-31</instant>
        </period>
    </context>
    <context id="As_Of_12_31_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_7IVaogKI6UuHMaADrJkhsA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">apre:ConvertiblePreferredStockSeriesaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:PreferredStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-12-31</instant>
        </period>
    </context>
    <context id="As_Of_12_31_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_m1QoLrlDGE-p35iHaQN70A">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">apre:ConvertiblePreferredStockSeriesaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-12-31</instant>
        </period>
    </context>
    <context id="As_Of_9_30_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_7gGY2uLNAUOrIeOyl0Yu3Q">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">apre:ConvertiblePreferredStockSeriesaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:PreferredStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="As_Of_6_30_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_R6HjfKfj2kC0Dts-tFsRHg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">apre:ConvertiblePreferredStockSeriesaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:PreferredStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-06-30</instant>
        </period>
    </context>
    <context id="As_Of_3_31_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_rhWtSSOwCkCaEzpIAh-drA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">apre:ConvertiblePreferredStockSeriesaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:PreferredStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-03-31</instant>
        </period>
    </context>
    <context id="As_Of_12_31_2022_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_8CsMqAUtn0GBba1hxVBFiQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">apre:ConvertiblePreferredStockSeriesaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:PreferredStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-12-31</instant>
        </period>
    </context>
    <context id="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_Paz762NlyEuz8le-TUK-tw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">apre:AtMarketOfferingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-01-01</startDate>
            <endDate>2023-03-31</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2023_To_3_31_2023_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_oHdcOW4hiEyfgESy4f5Jzw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">apre:AtMarketOfferingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-01-01</startDate>
            <endDate>2023-03-31</endDate>
        </period>
    </context>
    <context id="Duration_7_1_2024_To_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_uk8mlSyVokKTP3XSCE6G2g">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-07-01</startDate>
            <endDate>2024-09-30</endDate>
        </period>
    </context>
    <context id="Duration_7_1_2023_To_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_bnRcQIiX2Eip-CUgrzN4Ag">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-07-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2024_To_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_SIsBYxIs2kWHjyNmgCyPrQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-01-01</startDate>
            <endDate>2024-03-31</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_sqNgwBmbiUi7e68XTiWaJg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">apre:AtMarketOfferingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-01-01</startDate>
            <endDate>2023-03-31</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_GS2DrbBqyE-0nKgeaspqPg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-01-01</startDate>
            <endDate>2023-03-31</endDate>
        </period>
    </context>
    <context id="As_Of_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_7APo5uzuAUeE_AwHD_aDyQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-09-30</instant>
        </period>
    </context>
    <context id="As_Of_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_w6HcF2RyJ0OwVohdYcyrWg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-09-30</instant>
        </period>
    </context>
    <context id="As_Of_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_mLJ_odBxZ0OgdXDNP5Doaw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-09-30</instant>
        </period>
    </context>
    <context id="As_Of_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_3OjBHmrFdEqql1a9Qd1d4w">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-06-30</instant>
        </period>
    </context>
    <context id="As_Of_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_z5h7zepvB0S3yMqUDLxYRQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-06-30</instant>
        </period>
    </context>
    <context id="As_Of_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_kRMbWJwEh0W2ZdxtrlSp2g">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-06-30</instant>
        </period>
    </context>
    <context id="As_Of_6_30_2024_ZePgtrw-B0izH24xd1d8mw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <instant>2024-06-30</instant>
        </period>
    </context>
    <context id="As_Of_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_wfx449lO0kKvBkD-ftLx7w">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-03-31</instant>
        </period>
    </context>
    <context id="As_Of_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_Wi8LbADSoE6H9bs8u0MVsQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-03-31</instant>
        </period>
    </context>
    <context id="As_Of_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_lCnJPy7l60uydEVcNxwm6g">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-03-31</instant>
        </period>
    </context>
    <context id="As_Of_3_31_2024_Zvq5nTZZy0aWnnp0Yr_H1w">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <instant>2024-03-31</instant>
        </period>
    </context>
    <context id="As_Of_12_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_mNt4s5ToekueR3QLxsxleQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-12-31</instant>
        </period>
    </context>
    <context id="As_Of_12_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_GQCbRqVK3kuaSwxkX6qMKA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-12-31</instant>
        </period>
    </context>
    <context id="As_Of_12_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_yLYKKEjvoUy7Hx5o25CtFw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-12-31</instant>
        </period>
    </context>
    <context id="As_Of_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_ibhlFLDIRka5MzPbpPpzAQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="As_Of_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_6rGZcRyRUEmEmilgCL28PA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="As_Of_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_Ezbxq8ZdSkqMSQnvf2yPiw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="As_Of_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_mlp_Zv_4RkCOvMMVab-nCw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-06-30</instant>
        </period>
    </context>
    <context id="As_Of_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_yt6vg4-7Hk-CNT47e35gSQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-06-30</instant>
        </period>
    </context>
    <context id="As_Of_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_VtyWAB_w50KEUnNv-Oaekg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-06-30</instant>
        </period>
    </context>
    <context id="As_Of_6_30_2023_Lr_RTA-Vhk-vAvhygDZlMw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <instant>2023-06-30</instant>
        </period>
    </context>
    <context id="As_Of_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_XHftf8DOMkW2QPF25BFt1A">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-03-31</instant>
        </period>
    </context>
    <context id="As_Of_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_DvSHu5RNCU269rSppFYYgw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-03-31</instant>
        </period>
    </context>
    <context id="As_Of_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_3R6cMW1KKUK6IIoYqDNzqg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-03-31</instant>
        </period>
    </context>
    <context id="As_Of_3_31_2023_slQjcR-CEUatMT3-GnhwQA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <instant>2023-03-31</instant>
        </period>
    </context>
    <context id="As_Of_12_31_2022_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_-el1flLwfkGvk1hb4s7jRQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-12-31</instant>
        </period>
    </context>
    <context id="As_Of_12_31_2022_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_X-C6_R8tJE29iS3my5-mwA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-12-31</instant>
        </period>
    </context>
    <context id="As_Of_12_31_2022_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_fJbOuezCP0ukeyIR7_AUvw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-12-31</instant>
        </period>
    </context>
    <context id="As_Of_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_Omg5HL2Zk0iyUrhlyHkYzQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-09-30</instant>
        </period>
    </context>
    <context id="As_Of_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_pTVYFBxdF0KO7SAVt4uiIg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-06-30</instant>
        </period>
    </context>
    <context id="As_Of_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_BOEuDXy_ZUeMtyMb1W31eg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-03-31</instant>
        </period>
    </context>
    <context id="As_Of_12_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_tUhQ63t-YU-t2nhI1MP0bg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-12-31</instant>
        </period>
    </context>
    <context id="As_Of_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_jAvkAIbuQECJ-En9TI9QOw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="As_Of_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_5KgXuLcFS0y6eld2ApcJhw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-06-30</instant>
        </period>
    </context>
    <context id="As_Of_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_jLLZztnJSEaM57oF94_7xQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-03-31</instant>
        </period>
    </context>
    <context id="As_Of_12_31_2022_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_ep_zwMxd8Uy2Rb83GGZtEA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-12-31</instant>
        </period>
    </context>
    <context id="As_Of_2_28_2023_us-gaap_StatementClassOfStockAxis_us-gaap_CommonStockMember_us-gaap_SubsidiarySaleOfStockAxis_apre_ShelfRegistrationStatementMember_UBxEuMVTak-jJ5nG9mM16A">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">apre:ShelfRegistrationStatementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-02-28</instant>
        </period>
    </context>
    <context id="Duration_2_1_2023_To_2_28_2023_us-gaap_StatementClassOfStockAxis_us-gaap_CommonStockMember_us-gaap_SubsidiarySaleOfStockAxis_apre_ShelfRegistrationStatementMember_LaEYUb2hjkW2KGU-74xlQw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">apre:ShelfRegistrationStatementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-02-01</startDate>
            <endDate>2023-02-28</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2023_To_9_30_2023_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_fSqftKDYcEGIBNux4uAuoQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">apre:AtMarketOfferingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-01-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="Duration_7_1_2024_To_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_wNRC8dghckiqZHMJ2Qab2A">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-07-01</startDate>
            <endDate>2024-09-30</endDate>
        </period>
    </context>
    <context id="Duration_4_1_2024_To_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_fmrXxlAg8k2LTPqbZsdqQw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-04-01</startDate>
            <endDate>2024-06-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2024_To_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_alO13T8cuE2PUKMnkFcK4Q">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-01-01</startDate>
            <endDate>2024-03-31</endDate>
        </period>
    </context>
    <context id="Duration_7_1_2023_To_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_ZYusih75WEqqXs5jfU46kA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-07-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="Duration_4_1_2023_To_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_BnvW7lwu70SqT0ZU3Hyn2A">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-04-01</startDate>
            <endDate>2023-06-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_ZDYsshJEZkqk3c9XgeoP5A">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-01-01</startDate>
            <endDate>2023-03-31</endDate>
        </period>
    </context>
    <context id="Duration_7_1_2024_To_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_jqM4BFBbeUqa02lyUgxwnw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-07-01</startDate>
            <endDate>2024-09-30</endDate>
        </period>
    </context>
    <context id="Duration_4_1_2024_To_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_SbTatJBJOUiFH1taEFtwHQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-04-01</startDate>
            <endDate>2024-06-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2024_To_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_pA-2oAPYMEqk86sHU18u8Q">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-01-01</startDate>
            <endDate>2024-03-31</endDate>
        </period>
    </context>
    <context id="Duration_7_1_2023_To_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_JK8xHrjZfkqa45FOBphUpw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-07-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="Duration_4_1_2023_To_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_NMOLLFp0TUWc89OurulIXA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-04-01</startDate>
            <endDate>2023-06-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_hNmUQDanvk2hr1a2pdyeMA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-01-01</startDate>
            <endDate>2023-03-31</endDate>
        </period>
    </context>
    <context id="As_Of_9_30_2024_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_WAR5SHVFkE6tbDGoKuqOZg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:ClassOfWarrantOrRightAxis">apre:PreFundedWarrantsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">us-gaap:PrivatePlacementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-09-30</instant>
        </period>
    </context>
    <context id="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_Do28_zwKEkmVihgrJpKe5A">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CounterpartyNameAxis">apre:CertainPurchasersMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ClassOfWarrantOrRightAxis">apre:PreFundedWarrantsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">us-gaap:PrivatePlacementMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">apre:SecuritiesPurchaseAgreementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-03-11</instant>
        </period>
    </context>
    <context id="As_Of_12_31_2022_XHHJ56Sb40GzY2_iFyVSmw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <instant>2022-12-31</instant>
        </period>
    </context>
    <context id="As_Of_9_30_2023_8FQi5hYCckGx-AAVXCTMIQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="Duration_1_1_2024_To_9_30_2024_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_WarrantMember_18zK2B__vkKA8IrK9I5aKw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis">us-gaap:WarrantMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-01-01</startDate>
            <endDate>2024-09-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2024_To_9_30_2024_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_RestrictedStockUnitsRSUMember_BniNzMIFNESCAEERHrL4Qg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis">us-gaap:RestrictedStockUnitsRSUMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-01-01</startDate>
            <endDate>2024-09-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2024_To_9_30_2024_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_EmployeeStockOptionMember_lWBjcVjr5UKoPSricaY5kw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis">us-gaap:EmployeeStockOptionMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-01-01</startDate>
            <endDate>2024-09-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2024_To_9_30_2024_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_ConvertiblePreferredStockMember_-xdRwU9xSUiPNwUETulTXA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis">us-gaap:ConvertiblePreferredStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-01-01</startDate>
            <endDate>2024-09-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2023_To_9_30_2023_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_RestrictedStockUnitsRSUMember_V6BVG1ivukSZDtIV_eHuyA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis">us-gaap:RestrictedStockUnitsRSUMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-01-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2023_To_9_30_2023_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_EmployeeStockOptionMember_I-_Nu9K7KEKrfxHT-XiE6A">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis">us-gaap:EmployeeStockOptionMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-01-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2023_To_9_30_2023_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_ConvertiblePreferredStockMember_z_oRFQwZ_U2_FPccUncU4Q">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis">us-gaap:ConvertiblePreferredStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-01-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <startDate>2023-01-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="Duration_7_1_2024_To_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_Ddh4E4AbBEerRzR7f0tdRQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-07-01</startDate>
            <endDate>2024-09-30</endDate>
        </period>
    </context>
    <context id="Duration_4_1_2024_To_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_00YNAPouPUS3eodKEdKUZQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-04-01</startDate>
            <endDate>2024-06-30</endDate>
        </period>
    </context>
    <context id="Duration_4_1_2024_To_6_30_2024_fAYnBVLhzUG8aJvV8WQWcQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <startDate>2024-04-01</startDate>
            <endDate>2024-06-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2024_To_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_JmDXfNDeoU-A7sBdCGSkpw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-01-01</startDate>
            <endDate>2024-03-31</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2024_To_3_31_2024_k6qmi3YCyUeoj4EzQWmoYg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <startDate>2024-01-01</startDate>
            <endDate>2024-03-31</endDate>
        </period>
    </context>
    <context id="Duration_7_1_2023_To_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_44A8CawaA0CwnlBa7i0axg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-07-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <startDate>2023-07-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="Duration_4_1_2023_To_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_5LQIj-xrt0am4-0q7OB9Gw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-04-01</startDate>
            <endDate>2023-06-30</endDate>
        </period>
    </context>
    <context id="Duration_4_1_2023_To_6_30_2023_P0QiqJFu3ku16O4sijWHpw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <startDate>2023-04-01</startDate>
            <endDate>2023-06-30</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_60CYeoJMNkOFtTQ-EB4jYg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-01-01</startDate>
            <endDate>2023-03-31</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2023_To_3_31_2023_zTcMywQwh0-rXqoAlfNCWw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <startDate>2023-01-01</startDate>
            <endDate>2023-03-31</endDate>
        </period>
    </context>
    <context id="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <startDate>2024-07-01</startDate>
            <endDate>2024-09-30</endDate>
        </period>
    </context>
    <context id="As_Of_11_7_2024_rCC5Lx28V0yL1CVfxqJ0aQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <instant>2024-11-07</instant>
        </period>
    </context>
    <context id="As_Of_11_12_2020_us-gaap_SubsidiarySaleOfStockAxis_apre_ShelfRegistrationStatementMember_ARwQ47H460ieVrWA3BWUnQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">apre:ShelfRegistrationStatementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-11-12</instant>
        </period>
    </context>
    <context id="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice9.1125PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_G-a6RTBX2E2Sy0VISZQI2A">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CounterpartyNameAxis">apre:CertainPurchasersMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ClassOfWarrantOrRightAxis">apre:PreFundedWarrantsExercisePrice9.1125PerShareMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">us-gaap:PrivatePlacementMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">apre:SecuritiesPurchaseAgreementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-03-11</instant>
        </period>
    </context>
    <context id="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice7.29PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_lx_pDgysWkWXlV3jLs59hg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CounterpartyNameAxis">apre:CertainPurchasersMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ClassOfWarrantOrRightAxis">apre:PreFundedWarrantsExercisePrice7.29PerShareMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">us-gaap:PrivatePlacementMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">apre:SecuritiesPurchaseAgreementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-03-11</instant>
        </period>
    </context>
    <context id="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_srt_StatementScenarioAxis_apre_AtEventOfElectionOfHolderMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_jryn2JxtuUiScam-ie0pMg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CounterpartyNameAxis">apre:CertainPurchasersMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementScenarioAxis">apre:AtEventOfElectionOfHolderMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">us-gaap:PrivatePlacementMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">apre:SecuritiesPurchaseAgreementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-03-11</instant>
        </period>
    </context>
    <context id="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_5KoUULH39EatBTbigzb7Nw">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CounterpartyNameAxis">apre:CertainPurchasersMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">us-gaap:PrivatePlacementMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">apre:SecuritiesPurchaseAgreementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-03-11</instant>
        </period>
    </context>
    <context id="Duration_3_11_2024_To_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice9.1125PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_zOEchtkouU6yqqanDoFo6w">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CounterpartyNameAxis">apre:CertainPurchasersMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ClassOfWarrantOrRightAxis">apre:PreFundedWarrantsExercisePrice9.1125PerShareMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">us-gaap:PrivatePlacementMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">apre:SecuritiesPurchaseAgreementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-03-11</startDate>
            <endDate>2024-03-11</endDate>
        </period>
    </context>
    <context id="Duration_3_11_2024_To_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice7.29PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_2erKOwIbbU-vg-0HBwM-Ew">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CounterpartyNameAxis">apre:CertainPurchasersMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ClassOfWarrantOrRightAxis">apre:PreFundedWarrantsExercisePrice7.29PerShareMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">us-gaap:PrivatePlacementMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">apre:SecuritiesPurchaseAgreementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-03-11</startDate>
            <endDate>2024-03-11</endDate>
        </period>
    </context>
    <context id="Duration_3_11_2024_To_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_NhXjTaJGO0qzpt50WX1aQA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CounterpartyNameAxis">apre:CertainPurchasersMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">us-gaap:PrivatePlacementMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">apre:SecuritiesPurchaseAgreementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2024-03-11</startDate>
            <endDate>2024-03-11</endDate>
        </period>
    </context>
    <context id="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <startDate>2024-01-01</startDate>
            <endDate>2024-09-30</endDate>
        </period>
    </context>
    <context id="As_Of_1_26_2024_srt_CounterpartyNameAxis_apre_HCWainrightCoLlcMember_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarket2024OfferingMember_M05-gKo8P0qhKNNnCJ2ynA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CounterpartyNameAxis">apre:HCWainrightCoLlcMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">apre:AtMarket2024OfferingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-01-26</instant>
        </period>
    </context>
    <context id="As_Of_1_26_2024_us-gaap_SubsidiarySaleOfStockAxis_apre_ShelfRegistrationStatement2024Member_hof9NYm7h0ub2MpXywHosA">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">apre:ShelfRegistrationStatement2024Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2024-01-26</instant>
        </period>
    </context>
    <context id="As_Of_11_12_2020_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_gmVaaYo2B0i-Fejiwesclg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">apre:AtMarketOfferingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-11-12</instant>
        </period>
    </context>
    <context id="Duration_11_12_2020_To_11_12_2020_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_MJWqDGoHuUiO0gnEMhlZUg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:SubsidiarySaleOfStockAxis">apre:AtMarketOfferingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-11-12</startDate>
            <endDate>2020-11-12</endDate>
        </period>
    </context>
    <context id="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <instant>2024-09-30</instant>
        </period>
    </context>
    <context id="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001781983</identifier>
        </entity>
        <period>
            <instant>2023-12-31</instant>
        </period>
    </context>
    <unit id="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">
        <measure>iso4217:USD</measure>
    </unit>
    <unit id="Unit_Standard_pure_psC0V7jouEy1pdZ9EBR0Hw">
        <measure>pure</measure>
    </unit>
    <unit id="Unit_Standard_Vote_xLAtZ3mDNEadoQnTSpr_cQ">
        <measure>apre:Vote</measure>
    </unit>
    <unit id="Unit_Standard_lease_uug6S_kQsEij919rCVEEeQ">
        <measure>apre:lease</measure>
    </unit>
    <unit id="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">
        <divide>
            <unitNumerator>
                <measure>iso4217:USD</measure>
            </unitNumerator>
            <unitDenominator>
                <measure>shares</measure>
            </unitDenominator>
        </divide>
    </unit>
    <unit id="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">
        <measure>shares</measure>
    </unit>
    <us-gaap:CommitmentsAndContingencies
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      id="Hidden_-zPpJ3bRgkyQ0nxFFzF5lw"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw"
      xsi:nil="true"/>
    <us-gaap:CommitmentsAndContingencies
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      id="Hidden_GlMZNwmHW0qzOUsp9CRjlg"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw"
      xsi:nil="true"/>
    <dei:EntityCentralIndexKey
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tc_XKnPpj0gkkCLXqbRAjdmRA_1_1">0001781983</dei:EntityCentralIndexKey>
    <dei:CurrentFiscalYearEndDate
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tc_napIRieUEU25LorZQCOpFA_2_1">--12-31</dei:CurrentFiscalYearEndDate>
    <dei:DocumentFiscalYearFocus
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tc_CwTW4B8KwEOKj1yJhkVIpw_3_1">2024</dei:DocumentFiscalYearFocus>
    <dei:DocumentFiscalPeriodFocus
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tc_GrlxfBf1qEet2t2j3Gc_lQ_4_1">Q3</dei:DocumentFiscalPeriodFocus>
    <dei:AmendmentFlag
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tc_XX9aeEqGc0uSOa5ZWi8sjw_5_1">false</dei:AmendmentFlag>
    <us-gaap:CommonStockSharesOutstanding
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="INF"
      id="Hidden_81GrG1sLMEy1hqocEcqz_A"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">5434903</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:CommonStockSharesIssued
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="INF"
      id="Hidden_RER4QCFRiEqM4rJJHJIF8Q"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">3736673</us-gaap:CommonStockSharesIssued>
    <us-gaap:TemporaryEquitySharesOutstanding
      contextRef="As_Of_9_30_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_vRazHx54bUee8EgCl6bZxg"
      decimals="INF"
      id="Hidden_T0es8AYRy0ahzFENb_YA5A"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">56227</us-gaap:TemporaryEquitySharesOutstanding>
    <us-gaap:TemporaryEquitySharesOutstanding
      contextRef="As_Of_12_31_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_m1QoLrlDGE-p35iHaQN70A"
      decimals="INF"
      id="Hidden_CwFh2Lkz30mFTRIyKnV_og"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">56227</us-gaap:TemporaryEquitySharesOutstanding>
    <ecd:Rule10b51ArrAdoptedFlag
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      id="Hidden_crGT9flIcE6p7KBQXNYKVQ">false</ecd:Rule10b51ArrAdoptedFlag>
    <ecd:NonRule10b51ArrAdoptedFlag
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      id="Hidden_bgQIm2SdUki9zLB3cPayVA">false</ecd:NonRule10b51ArrAdoptedFlag>
    <ecd:Rule10b51ArrTrmntdFlag
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      id="Hidden_iA1bmvAgEkabBTZ1yPfd7g">false</ecd:Rule10b51ArrTrmntdFlag>
    <ecd:NonRule10b51ArrTrmntdFlag
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      id="Hidden_gT6Ck3ksFUm3M-K_GoMkjg">false</ecd:NonRule10b51ArrTrmntdFlag>
    <apre:LesseeOperatingLeaseAnnualBaseRentObligationAfterCurrentYear
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Hidden_dXY0fqi6LUqjrBt7mcO_tw"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">0</apre:LesseeOperatingLeaseAnnualBaseRentObligationAfterCurrentYear>
    <dei:DocumentType
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_3EyfGtKt4keo4c6_fk73Ow">10-Q</dei:DocumentType>
    <dei:DocumentQuarterlyReport
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_w0gcbDq8Y0-lDVN_QGJFAQ">true</dei:DocumentQuarterlyReport>
    <dei:DocumentPeriodEndDate
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_sB7B1yXT1Eqi7OUmWRRDtQ">2024-09-30</dei:DocumentPeriodEndDate>
    <dei:DocumentTransitionReport
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_G22wCT5rC025ytYgtEnqmw">false</dei:DocumentTransitionReport>
    <dei:EntityFileNumber
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_PSzfweh-q0CmlEk6Zbmp8Q">001-39069</dei:EntityFileNumber>
    <dei:EntityRegistrantName
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_ojBHyRfuIU-yLfD0HkKXaQ">Aprea Therapeutics, Inc.</dei:EntityRegistrantName>
    <dei:EntityIncorporationStateCountryCode
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tc_6ssEvX4HFUyAOw6CPms7vA_1_0">DE</dei:EntityIncorporationStateCountryCode>
    <dei:EntityTaxIdentificationNumber
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tc_Gu69SdIOok67RdkC-ejIiQ_1_1">84-2246769</dei:EntityTaxIdentificationNumber>
    <dei:EntityAddressAddressLine1
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tc_wzLS2aVhnEC2xb4qSAXwGQ_4_0">3805 Old Easton Road</dei:EntityAddressAddressLine1>
    <dei:EntityAddressCityOrTown
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_y41Qg7TG1kWkTvWB3OXf6w">Doylestown</dei:EntityAddressCityOrTown>
    <dei:EntityAddressStateOrProvince
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_wJasxAZpW0S0wgLumzRR_Q">PA</dei:EntityAddressStateOrProvince>
    <dei:EntityAddressPostalZipCode
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tc_8vVtiqNlCE2DSygFL1Kpqg_5_1">18902</dei:EntityAddressPostalZipCode>
    <dei:CityAreaCode
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_QKJzOCR1TU-hJgn6stk4AA">617</dei:CityAreaCode>
    <dei:LocalPhoneNumber
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_9_TxHZu_NUyLDP9q1WS0aQ">463-9385</dei:LocalPhoneNumber>
    <dei:Security12bTitle
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tc_P-tu_nVO6kWUmpn-GsQfsQ_1_0">Common stock, par value $0.001 per share</dei:Security12bTitle>
    <dei:TradingSymbol
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tc_PhsGREJQbEa0tMgS88zNvg_1_2">APRE</dei:TradingSymbol>
    <dei:SecurityExchangeName
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_rCNJGzOx60WSYn1O8RinCw">NASDAQ</dei:SecurityExchangeName>
    <dei:EntityCurrentReportingStatus
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_GiAzFkMRv0qtBZ8AX32WkQ">Yes</dei:EntityCurrentReportingStatus>
    <dei:EntityInteractiveDataCurrent
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_iJmIp6IRTU2w2xJCdKj7yQ">Yes</dei:EntityInteractiveDataCurrent>
    <dei:EntityFilerCategory
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_qba514AAzU67n8DjTcaNXQ">Non-accelerated Filer</dei:EntityFilerCategory>
    <dei:EntitySmallBusiness
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_yc7KsLwGeEmXF9XOThvrWg">true</dei:EntitySmallBusiness>
    <dei:EntityEmergingGrowthCompany
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_Xq-YVpI1VUWxoJlez3dpfw">true</dei:EntityEmergingGrowthCompany>
    <dei:EntityExTransitionPeriod
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_Yzrqj7RULESeNk-F_INK8Q">true</dei:EntityExTransitionPeriod>
    <dei:EntityShellCompany
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Narr_R4epJb8DE0CZFJUxC-6_vg">false</dei:EntityShellCompany>
    <dei:EntityCommonStockSharesOutstanding
      contextRef="As_Of_11_7_2024_rCC5Lx28V0yL1CVfxqJ0aQ"
      decimals="INF"
      id="Narr_W0_o68Wrn06Hp7RFBRwVVA"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">5434903</dei:EntityCommonStockSharesOutstanding>
    <us-gaap:CashAndCashEquivalentsAtCarryingValue
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_xwW35TRHikG2gd6kqiwslg_5_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">26249625</us-gaap:CashAndCashEquivalentsAtCarryingValue>
    <us-gaap:CashAndCashEquivalentsAtCarryingValue
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_6hmNAX_vfUypXc_dxTxKjw_5_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">21606820</us-gaap:CashAndCashEquivalentsAtCarryingValue>
    <us-gaap:PrepaidExpenseAndOtherAssetsCurrent
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_GpJBH-ibME6L-u3Ws7q0aA_6_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">234195</us-gaap:PrepaidExpenseAndOtherAssetsCurrent>
    <us-gaap:PrepaidExpenseAndOtherAssetsCurrent
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_3VirJ-6dL0-b7By9btMguw_6_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">914275</us-gaap:PrepaidExpenseAndOtherAssetsCurrent>
    <us-gaap:AssetsCurrent
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_-HQ_7mI41kepF7tIDOMqaA_7_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">26483820</us-gaap:AssetsCurrent>
    <us-gaap:AssetsCurrent
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_jX2RmYFcFE6K8PsTZ6lanA_7_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">22521095</us-gaap:AssetsCurrent>
    <us-gaap:PropertyPlantAndEquipmentNet
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_1q29ya2eskWzxSky3GfJEA_8_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">86950</us-gaap:PropertyPlantAndEquipmentNet>
    <us-gaap:PropertyPlantAndEquipmentNet
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_66ZnmiQRqUee3WJnATLdgg_8_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">88362</us-gaap:PropertyPlantAndEquipmentNet>
    <us-gaap:RestrictedCashNoncurrent
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_sGmvdS1hlUuxk6d_MEa-ng_9_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">41537</us-gaap:RestrictedCashNoncurrent>
    <us-gaap:RestrictedCashNoncurrent
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_SobIJs2yb06zlLhf3Kvv0A_9_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">40717</us-gaap:RestrictedCashNoncurrent>
    <us-gaap:OtherAssetsNoncurrent
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_CMsk6td60Ea1lYvFIXuT-Q_10_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">281662</us-gaap:OtherAssetsNoncurrent>
    <us-gaap:Assets
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_L9XfP9CCb0mieKdOOVB_Zg_11_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">26893969</us-gaap:Assets>
    <us-gaap:Assets
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_610Ua_jG1UWQ53-i2cBZ0g_11_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">22650174</us-gaap:Assets>
    <us-gaap:AccountsPayableCurrent
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_G8SMTKHz-EC9CD1sUoSmtw_14_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1153880</us-gaap:AccountsPayableCurrent>
    <us-gaap:AccountsPayableCurrent
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_j2RnaRuAiUSIXNpDgE-yNg_14_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1670369</us-gaap:AccountsPayableCurrent>
    <apre:AccruedLiabilitiesAndEmployeeRelatedLiabilitiesCurrent
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_DvCf-6xvzUSkG_4mtHOv9A_15_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">2482008</apre:AccruedLiabilitiesAndEmployeeRelatedLiabilitiesCurrent>
    <apre:AccruedLiabilitiesAndEmployeeRelatedLiabilitiesCurrent
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_WPDBb7I7_kiVHr1GMM2HBQ_15_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">2186262</apre:AccruedLiabilitiesAndEmployeeRelatedLiabilitiesCurrent>
    <us-gaap:DeferredRevenueCurrent
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_syxRxJg3KEaTYZIRFop_DQ_16_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">528974</us-gaap:DeferredRevenueCurrent>
    <us-gaap:LiabilitiesCurrent
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_nWTxQJptnUe7nDNsE5KWmA_17_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">3635888</us-gaap:LiabilitiesCurrent>
    <us-gaap:LiabilitiesCurrent
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_kLb6H9SqkU6vWVGatza3_A_17_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">4385605</us-gaap:LiabilitiesCurrent>
    <us-gaap:TemporaryEquityParOrStatedValuePerShare
      contextRef="As_Of_9_30_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_vRazHx54bUee8EgCl6bZxg"
      decimals="INF"
      id="Narr__V9i4AW9_k6mRdXL-u5v2g"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">0.001</us-gaap:TemporaryEquityParOrStatedValuePerShare>
    <us-gaap:TemporaryEquityParOrStatedValuePerShare
      contextRef="As_Of_12_31_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_m1QoLrlDGE-p35iHaQN70A"
      decimals="INF"
      id="Narr_ww2NYHLCo02p73H7Zokt4g"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">0.001</us-gaap:TemporaryEquityParOrStatedValuePerShare>
    <us-gaap:TemporaryEquitySharesAuthorized
      contextRef="As_Of_9_30_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_vRazHx54bUee8EgCl6bZxg"
      decimals="INF"
      id="Narr_fIcmEaL62Eee5WP5DnxjeQ"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">40000000</us-gaap:TemporaryEquitySharesAuthorized>
    <us-gaap:TemporaryEquitySharesAuthorized
      contextRef="As_Of_12_31_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_m1QoLrlDGE-p35iHaQN70A"
      decimals="INF"
      id="Narr_T_CcTl9AsEilG_lqrjgXlw"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">40000000</us-gaap:TemporaryEquitySharesAuthorized>
    <us-gaap:TemporaryEquitySharesIssued
      contextRef="As_Of_9_30_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_vRazHx54bUee8EgCl6bZxg"
      decimals="INF"
      id="Narr_Q-UyHMcmO0SXkeRavtxDKw"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">56227</us-gaap:TemporaryEquitySharesIssued>
    <us-gaap:TemporaryEquitySharesIssued
      contextRef="As_Of_12_31_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_m1QoLrlDGE-p35iHaQN70A"
      decimals="INF"
      id="Narr_AMl_s0_W7EKGp5DesUOxDQ"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">56227</us-gaap:TemporaryEquitySharesIssued>
    <us-gaap:TemporaryEquityCarryingAmountAttributableToParent
      contextRef="As_Of_9_30_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_vRazHx54bUee8EgCl6bZxg"
      decimals="0"
      id="Tc_7EHv4_rGN0aztZpi02rVYQ_19_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1311063</us-gaap:TemporaryEquityCarryingAmountAttributableToParent>
    <us-gaap:TemporaryEquityCarryingAmountAttributableToParent
      contextRef="As_Of_12_31_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_m1QoLrlDGE-p35iHaQN70A"
      decimals="0"
      id="Tc_FRVEsfynN0S5OW42AsVqgg_19_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1311063</us-gaap:TemporaryEquityCarryingAmountAttributableToParent>
    <us-gaap:CommonStockParOrStatedValuePerShare
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="INF"
      id="Narr_IzFUVydXVEqY14-FurjyBw"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">0.001</us-gaap:CommonStockParOrStatedValuePerShare>
    <us-gaap:CommonStockParOrStatedValuePerShare
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="INF"
      id="Narr_sRx6OH7OEUyR4jywFXrn9A"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">0.001</us-gaap:CommonStockParOrStatedValuePerShare>
    <us-gaap:CommonStockSharesAuthorized
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="INF"
      id="Narr_RHAFHvIrg0e4XRZ15Fw_sA"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">400000000</us-gaap:CommonStockSharesAuthorized>
    <us-gaap:CommonStockSharesAuthorized
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="INF"
      id="Narr_Utdo9x2l8Eq0_JHzixqffg"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">400000000</us-gaap:CommonStockSharesAuthorized>
    <us-gaap:CommonStockSharesIssued
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="INF"
      id="Narr_CeoWckkCGkC6kFFbaqU6Xg"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">5434903</us-gaap:CommonStockSharesIssued>
    <us-gaap:CommonStockSharesOutstanding
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="INF"
      id="Narr_02rt8iZOK0WyuG6e8v9Xvg"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">3736673</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:CommonStockValue
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_IB9CDappAUeSQeUyuvd7rw_21_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">5435</us-gaap:CommonStockValue>
    <us-gaap:CommonStockValue
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_hn7wXOOUmEy1bRtO2pQVMw_21_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">3736</us-gaap:CommonStockValue>
    <us-gaap:AdditionalPaidInCapital
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_p82MmbT6-0-t28Gb2HJ1lw_22_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">350693403</us-gaap:AdditionalPaidInCapital>
    <us-gaap:AdditionalPaidInCapital
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_k9oFhNleUkynEB1A7rfDjw_22_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">335644204</us-gaap:AdditionalPaidInCapital>
    <us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_UDrU77dll0uPN7MBnSPaXQ_23_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10604747</us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_x8t1Lq8Evk20wrORScWGKA_23_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10611273</us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:RetainedEarningsAccumulatedDeficit
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_R8mtH81G00-s4AqKkVIK9g_24_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-318147073</us-gaap:RetainedEarningsAccumulatedDeficit>
    <us-gaap:RetainedEarningsAccumulatedDeficit
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_Ia9vhyWi8kCx5yEU55i_IA_24_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-308083161</us-gaap:RetainedEarningsAccumulatedDeficit>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_MyabgoqC40S8zY8Uqwhf_Q_25_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">21947018</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_kqyHzXa8WUKQi1oMbl84wQ_25_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">16953506</us-gaap:StockholdersEquity>
    <us-gaap:LiabilitiesAndStockholdersEquity
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_G6d0rDvyI06c4U_RnSaZEg_26_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">26893969</us-gaap:LiabilitiesAndStockholdersEquity>
    <us-gaap:LiabilitiesAndStockholdersEquity
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_dhYvgRCBnkue2QssJiEqQg_26_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">22650174</us-gaap:LiabilitiesAndStockholdersEquity>
    <us-gaap:RevenueNotFromContractWithCustomer
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_7y_Xx6ROoEuyq-rLuifFIQ_3_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">354621</us-gaap:RevenueNotFromContractWithCustomer>
    <us-gaap:RevenueNotFromContractWithCustomer
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_ddvt6rKo4kKAztQ5EVTCcQ_3_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">319468</us-gaap:RevenueNotFromContractWithCustomer>
    <us-gaap:RevenueNotFromContractWithCustomer
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_ZJCmpVXFWUKB0E2md9d5lQ_3_9"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1296764</us-gaap:RevenueNotFromContractWithCustomer>
    <us-gaap:RevenueNotFromContractWithCustomer
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_s6oBQp0UJ06rQNpG8kmt3g_3_12"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">569156</us-gaap:RevenueNotFromContractWithCustomer>
    <us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_yITcHZEuqk-fAY00aoF2bg_5_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">2846399</us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost>
    <us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_oOoDLeUmzE-e81Mihua7hQ_5_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">2122603</us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost>
    <us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_YzR9eCMJTkODSf5km1tJIQ_5_9"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">7004451</us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost>
    <us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_EQl2UFcYo0eq5ymgj675kg_5_12"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">5581802</us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost>
    <us-gaap:GeneralAndAdministrativeExpense
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_iQkcGfVGTU-p2_dxc0jAnw_6_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1605238</us-gaap:GeneralAndAdministrativeExpense>
    <us-gaap:GeneralAndAdministrativeExpense
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_3e0K-4Cqs0qO8ANBNNFHhw_6_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1719715</us-gaap:GeneralAndAdministrativeExpense>
    <us-gaap:GeneralAndAdministrativeExpense
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_Rb8ynzCUYk2bjmG-pfr-mA_6_9"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">5385923</us-gaap:GeneralAndAdministrativeExpense>
    <us-gaap:GeneralAndAdministrativeExpense
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_Y7VuOiY1E0Oln5mHOe0wLA_6_12"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">6784388</us-gaap:GeneralAndAdministrativeExpense>
    <us-gaap:OperatingExpenses
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_pJ0Swk21b0qyxkjlB4FUrQ_7_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">4451637</us-gaap:OperatingExpenses>
    <us-gaap:OperatingExpenses
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_vGqvNxYTQkam4wsOmgxbHA_7_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">3842318</us-gaap:OperatingExpenses>
    <us-gaap:OperatingExpenses
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_6PD9TGIr10Wy_K7_jDWmyQ_7_9"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">12390374</us-gaap:OperatingExpenses>
    <us-gaap:OperatingExpenses
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_Twcp66QJG06omA2ntD4KSw_7_12"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">12366190</us-gaap:OperatingExpenses>
    <us-gaap:OperatingIncomeLoss
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_cACtO86oEE-nb6IbfvgyTg_8_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-4097016</us-gaap:OperatingIncomeLoss>
    <us-gaap:OperatingIncomeLoss
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_GiSotAG6ZkmOxUyLeQFNuQ_8_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3522850</us-gaap:OperatingIncomeLoss>
    <us-gaap:OperatingIncomeLoss
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_GORYa6gDJkC-7STYIRofeg_8_9"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-11093610</us-gaap:OperatingIncomeLoss>
    <us-gaap:OperatingIncomeLoss
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_jcbyP1wD0UWshqU1k_2AUQ_8_12"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-11797034</us-gaap:OperatingIncomeLoss>
    <us-gaap:InterestIncomeExpenseNonoperatingNet
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_lQ4wsYYrGEuW_RQ2_j9ulw_10_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">348741</us-gaap:InterestIncomeExpenseNonoperatingNet>
    <us-gaap:InterestIncomeExpenseNonoperatingNet
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_teuSu4Qnk0CKYgS_O78cPw_10_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">321215</us-gaap:InterestIncomeExpenseNonoperatingNet>
    <us-gaap:InterestIncomeExpenseNonoperatingNet
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_PnU4y0h67kKwJphCx8_fAg_10_9"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1014518</us-gaap:InterestIncomeExpenseNonoperatingNet>
    <us-gaap:InterestIncomeExpenseNonoperatingNet
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_EneG2cUihkSjL1BnOAxjIw_10_12"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">913846</us-gaap:InterestIncomeExpenseNonoperatingNet>
    <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_r0pOf9nJskmUOmyZEcVzBA_11_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-35494</us-gaap:ForeignCurrencyTransactionGainLossBeforeTax>
    <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_5wR7RpAhP0K8Ez-W50MOsA_11_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-2880</us-gaap:ForeignCurrencyTransactionGainLossBeforeTax>
    <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_DHm_G4UGbkyashh7Isyjvw_11_9"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">15180</us-gaap:ForeignCurrencyTransactionGainLossBeforeTax>
    <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_bT7QhfdONkqJlfvZRp-ptQ_11_12"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">39686</us-gaap:ForeignCurrencyTransactionGainLossBeforeTax>
    <us-gaap:OtherNonoperatingIncomeExpense
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_yAnRuydnYkyb0CGyPXQbug_12_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">313247</us-gaap:OtherNonoperatingIncomeExpense>
    <us-gaap:OtherNonoperatingIncomeExpense
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_-7vTNQR0FEmjqKxWgDSaiA_12_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">318335</us-gaap:OtherNonoperatingIncomeExpense>
    <us-gaap:OtherNonoperatingIncomeExpense
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_XCKY8Z0E00mY9z6bUhCuoQ_12_9"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1029698</us-gaap:OtherNonoperatingIncomeExpense>
    <us-gaap:OtherNonoperatingIncomeExpense
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_nm0lEou1OECjoHCHEUFynw_12_12"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">953532</us-gaap:OtherNonoperatingIncomeExpense>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_Gjx7df3vpESV5TgwiUz1uQ_13_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3783769</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_-a1dYDSGp0GuU331YUjksA_13_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3204515</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_d31DbBKb3kGC94AfWlFjIg_13_9"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10063912</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_JFuC-qrg_UKGciO0ZaSHgA_13_12"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10843502</us-gaap:NetIncomeLoss>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_SYY3bec_dUWcbhBEYcY-1w_15_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">23557</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_w0unpQdUKkiylkn65epYNg_15_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-1002</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_GIeEB23lDUiwYoYF0da5KQ_15_9"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">6526</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_q8rhOJU62kmU7GPxJ8IyWw_15_12"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-12466</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:ComprehensiveIncomeNetOfTax
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc__MEf_cTHNEu_Hl2hpPslMQ_16_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3760212</us-gaap:ComprehensiveIncomeNetOfTax>
    <us-gaap:ComprehensiveIncomeNetOfTax
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_uNjUnw3Ve0ez35gYCOxGeg_16_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3205517</us-gaap:ComprehensiveIncomeNetOfTax>
    <us-gaap:ComprehensiveIncomeNetOfTax
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_YMyG7bqgdE2bpYpgNdy_Kg_16_9"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10057386</us-gaap:ComprehensiveIncomeNetOfTax>
    <us-gaap:ComprehensiveIncomeNetOfTax
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_u47a4RwY5U2VFB_zGIw70w_16_12"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10855968</us-gaap:ComprehensiveIncomeNetOfTax>
    <us-gaap:EarningsPerShareBasic
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="2"
      id="Tc_BYOISHvoVUGifAaOX-50UQ_17_3"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">-0.64</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareDiluted
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="2"
      id="Tc_BYOISHvoVUGifAaOX-50UQ_17_3_2"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">-0.64</us-gaap:EarningsPerShareDiluted>
    <us-gaap:EarningsPerShareBasic
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="2"
      id="Tc_M413Etpf_k2VfBcfXzr6xg_17_6"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">-0.86</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareDiluted
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="2"
      id="Tc_M413Etpf_k2VfBcfXzr6xg_17_6_2"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">-0.86</us-gaap:EarningsPerShareDiluted>
    <us-gaap:EarningsPerShareBasic
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="2"
      id="Tc_a1vxov7CUkqlRXZkxgJWhA_17_9"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">-1.88</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareDiluted
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="2"
      id="Tc_a1vxov7CUkqlRXZkxgJWhA_17_9_2"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">-1.88</us-gaap:EarningsPerShareDiluted>
    <us-gaap:EarningsPerShareBasic
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="2"
      id="Tc_uFaRapRVrkaHM6IeJFMuzQ_17_12"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">-3.03</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareDiluted
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="2"
      id="Tc_uFaRapRVrkaHM6IeJFMuzQ_17_12_2"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">-3.03</us-gaap:EarningsPerShareDiluted>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_CCzNvXdEUUiLCd_TvgLd7Q_18_3"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">5939755</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_CCzNvXdEUUiLCd_TvgLd7Q_18_3_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">5939755</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_WW9VMFFrZk-O6AyGbnvl8w_18_6"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">3735176</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_WW9VMFFrZk-O6AyGbnvl8w_18_6_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">3735176</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_F7BRbzPD80S8-oz_3y-hnQ_18_9"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">5360579</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_F7BRbzPD80S8-oz_3y-hnQ_18_9_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">5360579</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_BnLGV-j-R0-7QFwEjdrhJg_18_12"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">3577482</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_BnLGV-j-R0-7QFwEjdrhJg_18_12_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">3577482</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:TemporaryEquitySharesOutstanding
      contextRef="As_Of_12_31_2022_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_8CsMqAUtn0GBba1hxVBFiQ"
      decimals="INF"
      id="Tc_rYJnYlIKmUKtoEbZyzKBIA_5_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">56227</us-gaap:TemporaryEquitySharesOutstanding>
    <us-gaap:TemporaryEquityCarryingAmountAttributableToParent
      contextRef="As_Of_12_31_2022_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_8CsMqAUtn0GBba1hxVBFiQ"
      decimals="0"
      id="Tc_N2MD-RF8jkSpkz38eNGJfg_5_5"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1311063</us-gaap:TemporaryEquityCarryingAmountAttributableToParent>
    <us-gaap:SharesOutstanding
      contextRef="As_Of_12_31_2022_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_ep_zwMxd8Uy2Rb83GGZtEA"
      decimals="INF"
      id="Tc_gJby4NOGZECrbmsenrs6PQ_5_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">2655269</us-gaap:SharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_12_31_2022_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_ep_zwMxd8Uy2Rb83GGZtEA"
      decimals="0"
      id="Tc_-2Om3geWA0O1M_K-ORrjNQ_5_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">2655</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_12_31_2022_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_X-C6_R8tJE29iS3my5-mwA"
      decimals="0"
      id="Tc_9d9ygiS_w0y1W6tg8g9UoA_5_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">330060836</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_12_31_2022_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_fJbOuezCP0ukeyIR7_AUvw"
      decimals="0"
      id="Tc_slq1pKZNUEODjk_BsxvddA_5_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10623408</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_12_31_2022_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_-el1flLwfkGvk1hb4s7jRQ"
      decimals="0"
      id="Tc_8YssXp_NaUKhCTUE3tMH2w_5_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-293796405</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_12_31_2022_XHHJ56Sb40GzY2_iFyVSmw"
      decimals="0"
      id="Tc_lZUwz_OJNU-XfcXFiyAjjQ_5_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">25643678</us-gaap:StockholdersEquity>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_GS2DrbBqyE-0nKgeaspqPg"
      decimals="INF"
      id="Tc_Gl5Jw6b1K0KaOQ8gfa6YJg_6_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">1050000</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:StockIssuedDuringPeriodValueNewIssues
      contextRef="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_GS2DrbBqyE-0nKgeaspqPg"
      decimals="0"
      id="Tc_2H0ieNUHA0q_5h48fejfrg_6_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1050</us-gaap:StockIssuedDuringPeriodValueNewIssues>
    <us-gaap:StockIssuedDuringPeriodValueNewIssues
      contextRef="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_60CYeoJMNkOFtTQ-EB4jYg"
      decimals="0"
      id="Tc_TZGzhsoFyUqSuIhx-dmeng_6_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">4870815</us-gaap:StockIssuedDuringPeriodValueNewIssues>
    <us-gaap:StockIssuedDuringPeriodValueNewIssues
      contextRef="Duration_1_1_2023_To_3_31_2023_zTcMywQwh0-rXqoAlfNCWw"
      decimals="0"
      id="Tc_AKXS8MAmZ0WBIBzv2VmRNg_6_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">4871865</us-gaap:StockIssuedDuringPeriodValueNewIssues>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_sqNgwBmbiUi7e68XTiWaJg"
      decimals="INF"
      id="Tc_UdVYTxVTSUaEMpC70fC7XA_7_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">26302</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:StockIssuedDuringPeriodValueNewIssues
      contextRef="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_sqNgwBmbiUi7e68XTiWaJg"
      decimals="0"
      id="Tc_V18kTdRnZkmMl77TRVVV-w_7_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">26</us-gaap:StockIssuedDuringPeriodValueNewIssues>
    <us-gaap:StockIssuedDuringPeriodValueNewIssues
      contextRef="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_Paz762NlyEuz8le-TUK-tw"
      decimals="0"
      id="Tc_-iXtGOiaNkWLa6jCfJkx_A_7_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">268099</us-gaap:StockIssuedDuringPeriodValueNewIssues>
    <us-gaap:StockIssuedDuringPeriodValueNewIssues
      contextRef="Duration_1_1_2023_To_3_31_2023_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_oHdcOW4hiEyfgESy4f5Jzw"
      decimals="0"
      id="Tc_EaFVj2x9mkCxNURHwrwVpg_7_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">268125</us-gaap:StockIssuedDuringPeriodValueNewIssues>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_60CYeoJMNkOFtTQ-EB4jYg"
      decimals="0"
      id="Tc_PFH4BHd6h0KJBkzIKaqf_Q_8_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">16244</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="Duration_1_1_2023_To_3_31_2023_zTcMywQwh0-rXqoAlfNCWw"
      decimals="0"
      id="Tc_dJWMkckVaUmdBOl875FRtg_8_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">16244</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_ZDYsshJEZkqk3c9XgeoP5A"
      decimals="0"
      id="Tc_SjPP6aTTgkS05x-qSm5NPw_9_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">61956</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_1_1_2023_To_3_31_2023_zTcMywQwh0-rXqoAlfNCWw"
      decimals="0"
      id="Tc_VkER0-aLIUevgH2-CvS-RA_9_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">61956</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_1_1_2023_To_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_hNmUQDanvk2hr1a2pdyeMA"
      decimals="0"
      id="Tc_5o2H9TRwxEOqgQHM-B2SFQ_10_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-4379890</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_1_1_2023_To_3_31_2023_zTcMywQwh0-rXqoAlfNCWw"
      decimals="0"
      id="Tc_TGKL6ZusVE2f7rzg231IRA_10_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-4379890</us-gaap:NetIncomeLoss>
    <us-gaap:TemporaryEquitySharesOutstanding
      contextRef="As_Of_3_31_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_rhWtSSOwCkCaEzpIAh-drA"
      decimals="INF"
      id="Tc_ax8xvdRxF0eHxkNWD0mZug_11_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">56227</us-gaap:TemporaryEquitySharesOutstanding>
    <us-gaap:TemporaryEquityCarryingAmountAttributableToParent
      contextRef="As_Of_3_31_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_rhWtSSOwCkCaEzpIAh-drA"
      decimals="0"
      id="Tc_cQZrGvEYBkywD5SKZwTOQA_11_5"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1311063</us-gaap:TemporaryEquityCarryingAmountAttributableToParent>
    <us-gaap:SharesOutstanding
      contextRef="As_Of_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_jLLZztnJSEaM57oF94_7xQ"
      decimals="INF"
      id="Tc_weAIF-6ElkeBrm7XfK_mdw_11_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">3731571</us-gaap:SharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_jLLZztnJSEaM57oF94_7xQ"
      decimals="0"
      id="Tc_Aovzn_X7FEafSPcd28Iheg_11_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">3731</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_DvSHu5RNCU269rSppFYYgw"
      decimals="0"
      id="Tc_Fc8IdYziZESdPJaa3i_m_A_11_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">335215994</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_3R6cMW1KKUK6IIoYqDNzqg"
      decimals="0"
      id="Tc_xE8GTP80uUyDk_lWj8c_Dg_11_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10561452</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_3_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_XHftf8DOMkW2QPF25BFt1A"
      decimals="0"
      id="Tc_RiDIs5sja0GNKeUHXdcZqQ_11_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-298176295</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_3_31_2023_slQjcR-CEUatMT3-GnhwQA"
      decimals="0"
      id="Tc_goFTpJ-bqkyAM_WDqnuJmw_11_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">26481978</us-gaap:StockholdersEquity>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="Duration_4_1_2023_To_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_5LQIj-xrt0am4-0q7OB9Gw"
      decimals="0"
      id="Tc_58jUGNEagEePu-xAEliPWQ_13_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">269323</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="Duration_4_1_2023_To_6_30_2023_P0QiqJFu3ku16O4sijWHpw"
      decimals="0"
      id="Tc_LQlZ1Ff090Sb8U08__ehcg_13_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">269323</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_4_1_2023_To_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_BnvW7lwu70SqT0ZU3Hyn2A"
      decimals="0"
      id="Tc_QKPz9QPc-EWM_xmRZPegug_14_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-73420</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_4_1_2023_To_6_30_2023_P0QiqJFu3ku16O4sijWHpw"
      decimals="0"
      id="Tc_Zjqu9LP7fESb5GM0eZCUnQ_14_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-73420</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_4_1_2023_To_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_NMOLLFp0TUWc89OurulIXA"
      decimals="0"
      id="Tc_qh0QxN4nCUuFwMDwCEC93Q_15_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3259097</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_4_1_2023_To_6_30_2023_P0QiqJFu3ku16O4sijWHpw"
      decimals="0"
      id="Tc_AQclITxQsUKS2bY7XStwoQ_15_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3259097</us-gaap:NetIncomeLoss>
    <us-gaap:TemporaryEquitySharesOutstanding
      contextRef="As_Of_6_30_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_R6HjfKfj2kC0Dts-tFsRHg"
      decimals="INF"
      id="Tc_Qy7_somJ9kKqceTu_sFS_Q_16_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">56227</us-gaap:TemporaryEquitySharesOutstanding>
    <us-gaap:TemporaryEquityCarryingAmountAttributableToParent
      contextRef="As_Of_6_30_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_R6HjfKfj2kC0Dts-tFsRHg"
      decimals="0"
      id="Tc_SOUY8tHo50y9PZTec3oyQQ_16_5"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1311063</us-gaap:TemporaryEquityCarryingAmountAttributableToParent>
    <us-gaap:SharesOutstanding
      contextRef="As_Of_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_5KgXuLcFS0y6eld2ApcJhw"
      decimals="INF"
      id="Tc_iwUFYWVYbkef2rSENk55tQ_16_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">3731571</us-gaap:SharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_5KgXuLcFS0y6eld2ApcJhw"
      decimals="0"
      id="Tc_3jR6znR6CEyW92w2SpPLXw_16_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">3731</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_yt6vg4-7Hk-CNT47e35gSQ"
      decimals="0"
      id="Tc_UPhKSI5wqk68OoCsIE0Exg_16_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">335485317</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_VtyWAB_w50KEUnNv-Oaekg"
      decimals="0"
      id="Tc_To-LrBbqL0SntT7i3xuKKg_16_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10634872</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_6_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_mlp_Zv_4RkCOvMMVab-nCw"
      decimals="0"
      id="Tc_gr3nUHCt-U-ndU61DuXAEA_16_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-301435392</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_6_30_2023_Lr_RTA-Vhk-vAvhygDZlMw"
      decimals="0"
      id="Tc_Zws_CVYYuUuctysOk2rndw_16_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">23418784</us-gaap:StockholdersEquity>
    <us-gaap:StockIssuedDuringPeriodSharesRestrictedStockAwardGross
      contextRef="Duration_7_1_2023_To_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_bnRcQIiX2Eip-CUgrzN4Ag"
      decimals="INF"
      id="Tc_1zUeHAdhj0-Zb-qnnmj17Q_18_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">5102</us-gaap:StockIssuedDuringPeriodSharesRestrictedStockAwardGross>
    <us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardGross
      contextRef="Duration_7_1_2023_To_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_bnRcQIiX2Eip-CUgrzN4Ag"
      decimals="0"
      id="Tc_aHEyEDRYaUaN1TSGso7f9g_18_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">5</us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardGross>
    <us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardGross
      contextRef="Duration_7_1_2023_To_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_44A8CawaA0CwnlBa7i0axg"
      decimals="0"
      id="Tc_EdHlBaf9RUCC3xuEnz1kaQ_18_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-5</us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardGross>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="Duration_7_1_2023_To_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_44A8CawaA0CwnlBa7i0axg"
      decimals="0"
      id="Tc_lpYT2VV7mUitWgULN5vpyw_19_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">76031</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_XSvVt1gRd0ap1cQ-G4yzrw_19_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">76031</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_7_1_2023_To_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_ZYusih75WEqqXs5jfU46kA"
      decimals="0"
      id="Tc_YZYNCDMUyUSAWi0suFHm0g_20_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-1002</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_PW4wOvLU30K9RhNyQnKXEw_20_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-1002</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_7_1_2023_To_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_JK8xHrjZfkqa45FOBphUpw"
      decimals="0"
      id="Tc_qJ3gZrut5kODQ9BzObcRbQ_21_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3204515</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Tc_a9x6kAVYFk-FmQhtDTAznQ_21_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3204515</us-gaap:NetIncomeLoss>
    <us-gaap:TemporaryEquitySharesOutstanding
      contextRef="As_Of_9_30_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_7gGY2uLNAUOrIeOyl0Yu3Q"
      decimals="INF"
      id="Tc_SxJCi4wonUywZFiHkOj65w_22_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">56227</us-gaap:TemporaryEquitySharesOutstanding>
    <us-gaap:TemporaryEquityCarryingAmountAttributableToParent
      contextRef="As_Of_9_30_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_7gGY2uLNAUOrIeOyl0Yu3Q"
      decimals="0"
      id="Tc_dB85EOhWdUKHn2B12msSww_22_5"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1311063</us-gaap:TemporaryEquityCarryingAmountAttributableToParent>
    <us-gaap:SharesOutstanding
      contextRef="As_Of_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_jAvkAIbuQECJ-En9TI9QOw"
      decimals="INF"
      id="Tc_63Oo28tpwkuX4A7n0YEvHA_22_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">3736673</us-gaap:SharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_jAvkAIbuQECJ-En9TI9QOw"
      decimals="0"
      id="Tc_jsnxbIRC7Ua8ifbTRgTt0A_22_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">3736</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_6rGZcRyRUEmEmilgCL28PA"
      decimals="0"
      id="Tc_eanh1mR0qkK6ozZ6En7NFw_22_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">335561343</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_Ezbxq8ZdSkqMSQnvf2yPiw"
      decimals="0"
      id="Tc_IpgLjsbQLUuxkhSv45w_jw_22_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10635874</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_9_30_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_ibhlFLDIRka5MzPbpPpzAQ"
      decimals="0"
      id="Tc_uhMDXllJwkuNE8kTdLPO-g_22_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-304639907</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_9_30_2023_8FQi5hYCckGx-AAVXCTMIQ"
      decimals="0"
      id="Tc_EI6K793eBkOT5QzbaLq78g_22_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">20289298</us-gaap:StockholdersEquity>
    <us-gaap:TemporaryEquitySharesOutstanding
      contextRef="As_Of_12_31_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_7IVaogKI6UuHMaADrJkhsA"
      decimals="INF"
      id="Tc_is5H_HkXDEaQRTyApAsJpA_24_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">56227</us-gaap:TemporaryEquitySharesOutstanding>
    <us-gaap:TemporaryEquityCarryingAmountAttributableToParent
      contextRef="As_Of_12_31_2023_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_7IVaogKI6UuHMaADrJkhsA"
      decimals="0"
      id="Tc_uuBemZZmx0-T-IZKni1PEA_24_5"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1311063</us-gaap:TemporaryEquityCarryingAmountAttributableToParent>
    <us-gaap:SharesOutstanding
      contextRef="As_Of_12_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_tUhQ63t-YU-t2nhI1MP0bg"
      decimals="INF"
      id="Tc_f7UbBznXp0qSGFYOYeo8GQ_24_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">3736673</us-gaap:SharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_12_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_tUhQ63t-YU-t2nhI1MP0bg"
      decimals="0"
      id="Tc_502LkiTAOEKLfBBnRit3_g_24_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">3736</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_12_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_GQCbRqVK3kuaSwxkX6qMKA"
      decimals="0"
      id="Tc_NEUS4kCIkUGCZtK1Mf_Tpw_24_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">335644204</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_12_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_yLYKKEjvoUy7Hx5o25CtFw"
      decimals="0"
      id="Tc_TuZyCX6LekSK3FcKPUk9rw_24_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10611273</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_12_31_2023_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_mNt4s5ToekueR3QLxsxleQ"
      decimals="0"
      id="Tc_eRzrSu0qVkmXSE4wCmwm8Q_24_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-308083161</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_txOc2BkAQE-746oI_IigeA_24_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">16953506</us-gaap:StockholdersEquity>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="Duration_1_1_2024_To_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_SIsBYxIs2kWHjyNmgCyPrQ"
      decimals="INF"
      id="Tc_JtN92iCFXE253ZvLNvCs-Q_25_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">1687712</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:StockIssuedDuringPeriodValueNewIssues
      contextRef="Duration_1_1_2024_To_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_SIsBYxIs2kWHjyNmgCyPrQ"
      decimals="0"
      id="Tc_-GtKXuNoJES_Oh2l543NGQ_25_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1688</us-gaap:StockIssuedDuringPeriodValueNewIssues>
    <us-gaap:StockIssuedDuringPeriodValueNewIssues
      contextRef="Duration_1_1_2024_To_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_JmDXfNDeoU-A7sBdCGSkpw"
      decimals="0"
      id="Tc_b_2Cc4onAka7mYa8yZwnlg_25_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">14708017</us-gaap:StockIssuedDuringPeriodValueNewIssues>
    <us-gaap:StockIssuedDuringPeriodValueNewIssues
      contextRef="Duration_1_1_2024_To_3_31_2024_k6qmi3YCyUeoj4EzQWmoYg"
      decimals="0"
      id="Tc_CQO3rWVbEEqYhkFz0y0Wgw_25_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">14709705</us-gaap:StockIssuedDuringPeriodValueNewIssues>
    <us-gaap:StockIssuedDuringPeriodSharesRestrictedStockAwardGross
      contextRef="Duration_1_1_2024_To_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_SIsBYxIs2kWHjyNmgCyPrQ"
      decimals="INF"
      id="Tc_s0BkeOazmkKLs1_bilfYGA_26_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">5830</us-gaap:StockIssuedDuringPeriodSharesRestrictedStockAwardGross>
    <us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardGross
      contextRef="Duration_1_1_2024_To_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_SIsBYxIs2kWHjyNmgCyPrQ"
      decimals="0"
      id="Tc_bEuV6eerHE-8_rmot_Vjrw_26_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">6</us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardGross>
    <us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardGross
      contextRef="Duration_1_1_2024_To_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_JmDXfNDeoU-A7sBdCGSkpw"
      decimals="0"
      id="Tc_J_NnGop33ECcL-Xis1lrnw_26_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-6</us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardGross>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="Duration_1_1_2024_To_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_JmDXfNDeoU-A7sBdCGSkpw"
      decimals="0"
      id="Tc_bi9HuC2pqkSj4H9A3i-OdQ_27_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">85830</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="Duration_1_1_2024_To_3_31_2024_k6qmi3YCyUeoj4EzQWmoYg"
      decimals="0"
      id="Tc_INs23ZkBr0-bnLHKk2E2PA_27_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">85830</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_1_1_2024_To_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_alO13T8cuE2PUKMnkFcK4Q"
      decimals="0"
      id="Tc_C1p-HqRkqUSsh96ddf9OfQ_28_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-15083</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_1_1_2024_To_3_31_2024_k6qmi3YCyUeoj4EzQWmoYg"
      decimals="0"
      id="Tc_2V0hjTGqFUWHA66-afbUUw_28_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-15083</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_1_1_2024_To_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_pA-2oAPYMEqk86sHU18u8Q"
      decimals="0"
      id="Tc_mLcBVJw9GEqM14aB6TRuig_29_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-2810091</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_1_1_2024_To_3_31_2024_k6qmi3YCyUeoj4EzQWmoYg"
      decimals="0"
      id="Tc_RwnYD04C0UCmTyultyETnw_29_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-2810091</us-gaap:NetIncomeLoss>
    <us-gaap:TemporaryEquitySharesOutstanding
      contextRef="As_Of_3_31_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_liwNe_OrZkuTHNDpnZcmag"
      decimals="INF"
      id="Tc_oLxASaoHiUKHeXnWnCoU0A_30_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">56227</us-gaap:TemporaryEquitySharesOutstanding>
    <us-gaap:TemporaryEquityCarryingAmountAttributableToParent
      contextRef="As_Of_3_31_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_liwNe_OrZkuTHNDpnZcmag"
      decimals="0"
      id="Tc_DF0PTZU_uUOh0BIzg2vv9w_30_5"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1311063</us-gaap:TemporaryEquityCarryingAmountAttributableToParent>
    <us-gaap:SharesOutstanding
      contextRef="As_Of_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_BOEuDXy_ZUeMtyMb1W31eg"
      decimals="INF"
      id="Tc_Rj-Ucl0f0UqsJHArFKZaEQ_30_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">5430215</us-gaap:SharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_BOEuDXy_ZUeMtyMb1W31eg"
      decimals="0"
      id="Tc_20TxZIpBJkaaB6UW_Yq-Tw_30_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">5430</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_Wi8LbADSoE6H9bs8u0MVsQ"
      decimals="0"
      id="Tc_dIBOXoQAdEOW1r7iaUqwVQ_30_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">350438045</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_lCnJPy7l60uydEVcNxwm6g"
      decimals="0"
      id="Tc_PhGDturCZka3LhawtgdD8A_30_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10626356</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_3_31_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_wfx449lO0kKvBkD-ftLx7w"
      decimals="0"
      id="Tc_wDHGrFlnkUWT9q0ee9t9_g_30_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-310893252</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_3_31_2024_Zvq5nTZZy0aWnnp0Yr_H1w"
      decimals="0"
      id="Tc_cetyQA1NdkCwYjZHJJ2_6A_30_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">28923867</us-gaap:StockholdersEquity>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts
      contextRef="Duration_4_1_2024_To_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_00YNAPouPUS3eodKEdKUZQ"
      decimals="0"
      id="Tc_ELSTK5OGVkiepBqLX7gHfw_32_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">21060</us-gaap:AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts
      contextRef="Duration_4_1_2024_To_6_30_2024_fAYnBVLhzUG8aJvV8WQWcQ"
      decimals="0"
      id="Tc_W2OCHiciskGAx_Q-smyp3Q_32_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">21060</us-gaap:AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="Duration_4_1_2024_To_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_00YNAPouPUS3eodKEdKUZQ"
      decimals="0"
      id="Tc_gXw8mwKWlU6LRhsTVFXIXw_33_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">128488</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="Duration_4_1_2024_To_6_30_2024_fAYnBVLhzUG8aJvV8WQWcQ"
      decimals="0"
      id="Tc_oLJpawGesESlVmuxgjoobQ_33_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">128488</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_4_1_2024_To_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_fmrXxlAg8k2LTPqbZsdqQw"
      decimals="0"
      id="Tc_rLRxlXmfTE228VQibOQ7yw_34_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-1948</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_4_1_2024_To_6_30_2024_fAYnBVLhzUG8aJvV8WQWcQ"
      decimals="0"
      id="Tc_VFM1Q7atxk-LyWeIYbwflg_34_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-1948</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_4_1_2024_To_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_SbTatJBJOUiFH1taEFtwHQ"
      decimals="0"
      id="Tc_BCgAz4PX8ECdxHIomRtlxA_35_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3470052</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_4_1_2024_To_6_30_2024_fAYnBVLhzUG8aJvV8WQWcQ"
      decimals="0"
      id="Tc_8nlOTVObRUS7svFJ1WkXqg_35_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3470052</us-gaap:NetIncomeLoss>
    <us-gaap:TemporaryEquitySharesOutstanding
      contextRef="As_Of_6_30_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_MQGoU-f5K02GZ9PlM-yOkA"
      decimals="INF"
      id="Tc_ZQVfN2jzY0SChWCPBqkOBA_36_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">56227</us-gaap:TemporaryEquitySharesOutstanding>
    <us-gaap:TemporaryEquityCarryingAmountAttributableToParent
      contextRef="As_Of_6_30_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_MQGoU-f5K02GZ9PlM-yOkA"
      decimals="0"
      id="Tc_VeHMKDZVnUmYYxij1Wcpkg_36_5"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1311063</us-gaap:TemporaryEquityCarryingAmountAttributableToParent>
    <us-gaap:SharesOutstanding
      contextRef="As_Of_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_pTVYFBxdF0KO7SAVt4uiIg"
      decimals="INF"
      id="Tc_qbk8jpjWNUOgI4Jd3e59hg_36_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">5430215</us-gaap:SharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_pTVYFBxdF0KO7SAVt4uiIg"
      decimals="0"
      id="Tc_90JYYeMYKkOEwkLiE6Bl7Q_36_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">5430</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_z5h7zepvB0S3yMqUDLxYRQ"
      decimals="0"
      id="Tc_DrECCqGVS0eKehXfyfAH4g_36_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">350545473</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_kRMbWJwEh0W2ZdxtrlSp2g"
      decimals="0"
      id="Tc_3oaFCXqwJESVIWVbw8TU9w_36_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10628304</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_6_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_3OjBHmrFdEqql1a9Qd1d4w"
      decimals="0"
      id="Tc_aRs8y1oe6k606zdmcjwkeQ_36_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-314363304</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_6_30_2024_ZePgtrw-B0izH24xd1d8mw"
      decimals="0"
      id="Tc_nAUYZ59yN0ixEdyV6uq6yQ_36_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">25559295</us-gaap:StockholdersEquity>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts
      contextRef="Duration_7_1_2024_To_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_Ddh4E4AbBEerRzR7f0tdRQ"
      decimals="0"
      id="Tc_qqTVArkW_EKD6wDcc49_XA_38_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1155</us-gaap:AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_SfxR5orYmkqu1C1xYuuu_A_38_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1155</us-gaap:AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts>
    <us-gaap:StockIssuedDuringPeriodSharesRestrictedStockAwardGross
      contextRef="Duration_7_1_2024_To_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_uk8mlSyVokKTP3XSCE6G2g"
      decimals="INF"
      id="Tc_KIwqepWFSEurnCt61t_htw_39_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">4688</us-gaap:StockIssuedDuringPeriodSharesRestrictedStockAwardGross>
    <us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardGross
      contextRef="Duration_7_1_2024_To_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_uk8mlSyVokKTP3XSCE6G2g"
      decimals="0"
      id="Tc_N1-gr3wjUUmZQzopvK7AVA_39_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">5</us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardGross>
    <us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardGross
      contextRef="Duration_7_1_2024_To_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_Ddh4E4AbBEerRzR7f0tdRQ"
      decimals="0"
      id="Tc_dbn6qIPNeUm-k-GoeJjxkw_39_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-5</us-gaap:StockIssuedDuringPeriodValueRestrictedStockAwardGross>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="Duration_7_1_2024_To_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_Ddh4E4AbBEerRzR7f0tdRQ"
      decimals="0"
      id="Tc_sJUng0xS1kWa26TT1ttK8g_40_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">149090</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_uO2DP1y5Tk-o8k77X6k_rA_40_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">149090</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_7_1_2024_To_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_wNRC8dghckiqZHMJ2Qab2A"
      decimals="0"
      id="Tc_ihOf5Z-JdkmitOkqCugwUQ_41_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">23557</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_LhSz1FXEFEquHwmIJr070Q_41_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">23557</us-gaap:OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_7_1_2024_To_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_jqM4BFBbeUqa02lyUgxwnw"
      decimals="0"
      id="Tc_CBja0fVZhUirP3pnJa70jQ_42_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3783769</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Tc_5yPaoXcW1U2U5_FrMmwTfw_42_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3783769</us-gaap:NetIncomeLoss>
    <us-gaap:TemporaryEquitySharesOutstanding
      contextRef="As_Of_9_30_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_8visgBbaHUi1WL8smvF9Lg"
      decimals="INF"
      id="Tc_SIU0NfKtAUOJYofxOJx4eQ_43_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">56227</us-gaap:TemporaryEquitySharesOutstanding>
    <us-gaap:TemporaryEquityCarryingAmountAttributableToParent
      contextRef="As_Of_9_30_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_us-gaap_StatementEquityComponentsAxis_us-gaap_PreferredStockMember_8visgBbaHUi1WL8smvF9Lg"
      decimals="0"
      id="Tc_LNQK1zSDK0OCFEMWQmA5RA_43_5"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1311063</us-gaap:TemporaryEquityCarryingAmountAttributableToParent>
    <us-gaap:SharesOutstanding
      contextRef="As_Of_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_Omg5HL2Zk0iyUrhlyHkYzQ"
      decimals="INF"
      id="Tc_zhjCrA09TkGlEH4SzdYCvQ_43_7"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">5434903</us-gaap:SharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_CommonStockMember_Omg5HL2Zk0iyUrhlyHkYzQ"
      decimals="0"
      id="Tc_wOdablRwJUWW1ykGVWhTqw_43_10"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">5435</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AdditionalPaidInCapitalMember_w6HcF2RyJ0OwVohdYcyrWg"
      decimals="0"
      id="Tc_i3KFprF0gE-ftkZJfLVbng_43_13"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">350693403</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_AccumulatedOtherComprehensiveIncomeMember_mLJ_odBxZ0OgdXDNP5Doaw"
      decimals="0"
      id="Tc_NlitUHHPYUmQZl-ab1S4HQ_43_16"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10604747</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_9_30_2024_us-gaap_StatementEquityComponentsAxis_us-gaap_RetainedEarningsMember_7APo5uzuAUeE_AwHD_aDyQ"
      decimals="0"
      id="Tc_BxTBDTKQBU2fhKBuLA1bXw_43_19"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-318147073</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_iwwPbiox6E2qUizsV8Yl0A_43_22"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">21947018</us-gaap:StockholdersEquity>
    <us-gaap:ProfitLoss
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_E6xUcTdyakuJbGtov2eIaQ_4_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10063912</us-gaap:ProfitLoss>
    <us-gaap:ProfitLoss
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_R8Knvky9EkOReX2iuNX-Sw_4_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10843502</us-gaap:ProfitLoss>
    <us-gaap:DepreciationDepletionAndAmortization
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_wMC1oh2qE067hY-7gf47rA_6_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">16890</us-gaap:DepreciationDepletionAndAmortization>
    <us-gaap:DepreciationDepletionAndAmortization
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_xS-cmM5RcUS6z8RB_9K7Yg_6_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">2066</us-gaap:DepreciationDepletionAndAmortization>
    <us-gaap:EmployeeBenefitsAndShareBasedCompensationNoncash
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_aVimeM__bkaUhjnF6upm7g_7_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">363408</us-gaap:EmployeeBenefitsAndShareBasedCompensationNoncash>
    <us-gaap:EmployeeBenefitsAndShareBasedCompensationNoncash
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_kKNvnMy8x0uaejvkej2ROw_7_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">361598</us-gaap:EmployeeBenefitsAndShareBasedCompensationNoncash>
    <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_2lEC7ksPrUKDtpBfD3ZASw_8_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">15180</us-gaap:ForeignCurrencyTransactionGainLossBeforeTax>
    <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_a6O_7wYhrUaO65kKAbyF_w_8_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">39686</us-gaap:ForeignCurrencyTransactionGainLossBeforeTax>
    <us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_9Koi3yWe_USOujYy23nyPQ_10_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-398531</us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets>
    <us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_ayc7qxDpnEKDSC5haHJWdQ_10_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-1077138</us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets>
    <us-gaap:IncreaseDecreaseInAccountsPayable
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_FhjMNFpPz0e5xD4cv5Dt_w_11_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-515964</us-gaap:IncreaseDecreaseInAccountsPayable>
    <us-gaap:IncreaseDecreaseInAccountsPayable
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_Ax9FROEw6ECueY8hxbjq6Q_11_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">21873</us-gaap:IncreaseDecreaseInAccountsPayable>
    <us-gaap:IncreaseDecreaseInAccruedLiabilities
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_7_eNzTsIt0qa4nCVgVJyqA_12_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">299387</us-gaap:IncreaseDecreaseInAccruedLiabilities>
    <us-gaap:IncreaseDecreaseInAccruedLiabilities
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_nxvdP25JkU6kzIxvJtWHlw_12_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">982563</us-gaap:IncreaseDecreaseInAccruedLiabilities>
    <us-gaap:IncreaseDecreaseInDeferredRevenue
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_VMKFVvl94EGcyanBhHOfhA_13_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-528974</us-gaap:IncreaseDecreaseInDeferredRevenue>
    <us-gaap:NetCashProvidedByUsedInOperatingActivities
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_8aSI2cRW3UCU6SvDW6g-Zw_14_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-10045814</us-gaap:NetCashProvidedByUsedInOperatingActivities>
    <us-gaap:NetCashProvidedByUsedInOperatingActivities
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_9WMCVT0CI0idQDC1mHVacA_14_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-8437950</us-gaap:NetCashProvidedByUsedInOperatingActivities>
    <us-gaap:PaymentsToAcquirePropertyPlantAndEquipment
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_3078a0AMJ0C8aLuZa9QkEA_16_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">15478</us-gaap:PaymentsToAcquirePropertyPlantAndEquipment>
    <us-gaap:PaymentsToAcquirePropertyPlantAndEquipment
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_MdnOIdkB7EK9gdtXOoHzAw_16_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">85943</us-gaap:PaymentsToAcquirePropertyPlantAndEquipment>
    <us-gaap:NetCashProvidedByUsedInInvestingActivities
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_FU9-x1wnV0WLjyoZb-pZBw_17_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-15478</us-gaap:NetCashProvidedByUsedInInvestingActivities>
    <us-gaap:NetCashProvidedByUsedInInvestingActivities
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_RFVoCFxkGU2TQ3j9JoeLQw_17_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-85943</us-gaap:NetCashProvidedByUsedInInvestingActivities>
    <us-gaap:ProceedsFromIssuanceOfCommonStock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_ve8iv9D9zkGM_KbOpDeNDw_19_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">15999598</us-gaap:ProceedsFromIssuanceOfCommonStock>
    <us-gaap:ProceedsFromIssuanceOfCommonStock
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_XP4SmZ4CUESJJjMRIlad_w_19_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">5788918</us-gaap:ProceedsFromIssuanceOfCommonStock>
    <us-gaap:PaymentsOfStockIssuanceCosts
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_GS2eKvY0fEWLSDcEcQ1Mtg_20_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1312108</us-gaap:PaymentsOfStockIssuanceCosts>
    <us-gaap:PaymentsOfStockIssuanceCosts
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_KS-TISJsBEiIHaB_SGxApA_20_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">648928</us-gaap:PaymentsOfStockIssuanceCosts>
    <us-gaap:NetCashProvidedByUsedInFinancingActivities
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_21HEAg_oS0KpYh-nYm0rzw_21_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">14687490</us-gaap:NetCashProvidedByUsedInFinancingActivities>
    <us-gaap:NetCashProvidedByUsedInFinancingActivities
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_EGEHlyoq_UClxeF8W2oVAg_21_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">5139990</us-gaap:NetCashProvidedByUsedInFinancingActivities>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_xnNRDbyUMUmYGC_A9nLvVw_22_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">4626198</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_NFXWDFP4S0SwJCYnDSSWjQ_22_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-3383903</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect>
    <us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Tc_UA3AZJRhdEqDwmW_ntNd5Q_23_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">17427</us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations>
    <us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Tc_0WZZc6xVk0SJNu6k35WfOA_23_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">-8782</us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_YLm40TYIEkO4yUUHoxni2w_24_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">21647537</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
      contextRef="As_Of_12_31_2022_XHHJ56Sb40GzY2_iFyVSmw"
      decimals="0"
      id="Tc_17qOXeXOCEqBkufiqi0gXA_24_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">28786647</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_ah3Z_wHXtEaEG75XmY6pGA_25_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">26291162</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
      contextRef="As_Of_9_30_2023_8FQi5hYCckGx-AAVXCTMIQ"
      decimals="0"
      id="Tc_lQa3zhiJ-EufanUosTfIPA_25_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">25393962</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:CashAndCashEquivalentsAtCarryingValue
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_uAH4rAPjEkqvT0PBo0s8Hw_28_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">26249625</us-gaap:CashAndCashEquivalentsAtCarryingValue>
    <us-gaap:CashAndCashEquivalentsAtCarryingValue
      contextRef="As_Of_9_30_2023_8FQi5hYCckGx-AAVXCTMIQ"
      decimals="0"
      id="Tc_UM7ZHtXWS0mDfmePnNEbvg_28_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">25353513</us-gaap:CashAndCashEquivalentsAtCarryingValue>
    <us-gaap:RestrictedCash
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_yGKDC_AP3E2LwXJ8z5IrkA_29_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">41537</us-gaap:RestrictedCash>
    <us-gaap:RestrictedCash
      contextRef="As_Of_9_30_2023_8FQi5hYCckGx-AAVXCTMIQ"
      decimals="0"
      id="Tc_Ty6yjJITAE6QaPW7lZFd8w_29_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">40449</us-gaap:RestrictedCash>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_a6qNa-ezyEGLWn3I4HZiQw_30_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">26291162</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
      contextRef="As_Of_9_30_2023_8FQi5hYCckGx-AAVXCTMIQ"
      decimals="0"
      id="Tc_e09gepk1Uk2wKqkDYeH13w_30_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">25393962</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_4hMiYW5Kv0uZlXk3aNT0EQ">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;1. Nature of business and basis of presentation&lt;/b&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Nature of business&lt;/b&gt;&lt;span style="white-space:pre-wrap;"&gt;&#x2014;Aprea Therapeutics, Inc. (the &#x201c;Company&#x201d;) is a clinical-stage biopharmaceutical company focused on precision oncology through synthetic lethality. The Company began principal operations in 2006 and is headquartered in Doylestown, Pennsylvania.  Prior to the acquisition of Atrin Pharmaceuticals Inc. (&#x201c;Atrin&#x201d;) in May 2022, the Company was engaged in the clinical development of cancer therapeutics that reactivate the mutant p53 tumor suppressor protein. In December 2020, the Company announced that its pivotal Phase 3 myelodysplastic syndromes trial failed to meet its predefined primary endpoint of complete remission (CR) rate. Given these results, FDA feedback and the costs of continuing the APR-246 development program, the Company shifted focus of its activities to the assets acquired in the May 2022 acquisition of Atrin. The Company&#x2019;s two clinical programs are a novel oral macrocyclic ATR inhibitor, ATRN-119, and our next-generation oral inhibitor of the WEE1 kinase, APR-1051. Both programs are the cornerstones of our pipeline of synthetic lethality-based cancer therapeutics and were internally discovered, developed, and evaluated by our dedicated team of chemists, scientists, and clinicians.&lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Basis of presentation and management plans&lt;/b&gt;&#x2014;The accompanying financial statements are prepared in conformity with accounting principles generally accepted in the United States (&#x201c;U.S.&#160;GAAP&#x201d;). The accompanying financial statements have been prepared on a going concern basis, which contemplates the realization of assets and the satisfaction of liabilities in the normal course of business.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;Since its inception, the Company has devoted substantially all of its efforts to business planning, clinical operations, research and development, recruiting management, technical staff, raising capital and has financed its operations through the issuance of convertible preferred stock and common stock.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The Company is subject to risks common to companies in the biopharmaceutical industry. There can be no assurance that the Company&#x2019;s research and development will be successfully completed, that adequate protection for the Company&#x2019;s intellectual property will be maintained, that any therapeutic products developed will obtain required regulatory approval or that any approved or consumer products will be commercially viable. Even if the Company&#x2019;s development efforts are successful, it is uncertain when, if ever, the Company will generate significant product sales.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The Company believes that the September&#160;30,&#160;2024 cash balance of approximately $26.2 million will be sufficient to fund the Company&#x2019;s operating expenses and capital expenditure requirements through at least twelve months from the date of issuance of these condensed consolidated financial statements. In the event that additional funds are not available thereafter, management would expect to significantly reduce expenditures to conserve cash, which would involve scaling back or curtailing new development activity.&lt;/p&gt;</us-gaap:OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock>
    <us-gaap:CashAndCashEquivalentsAtCarryingValue
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="-5"
      id="Narr_qFKatj8cIEOKUvJPAYFZcw"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">26200000</us-gaap:CashAndCashEquivalentsAtCarryingValue>
    <us-gaap:SignificantAccountingPoliciesTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_V89E-hcq5k2vWo_LtPPkEA">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-weight:bold;margin:0pt 0pt 12pt 0pt;"&gt;2. Summary of significant accounting policies&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The Company's complete listing of significant accounting policies are described in Note 2 to the Company's audited consolidated financial statements as of December&#160;31,&#160;2023 included in its annual report on Form 10-K filed with the Securities and Exchange Commission (the &#x201c;SEC&#x201d;).&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Principles of consolidation&lt;/b&gt;&#x2014;The consolidated financial statements include the accounts of the Company and its wholly owned subsidiaries Aprea Therapeutics AB, which was incorporated in May 2009, Aprea US,&#160;Inc., which was incorporated in June&#160;2016 and ATR Pharmaceuticals LLC which was incorporated in May 2022. Management has concluded it has a single reporting segment for purposes of reporting financial condition and results of operations. All intercompany transactions and balances have been eliminated.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Unaudited interim consolidated financial statements&lt;/b&gt;&#x2014;The accompanying unaudited interim condensed consolidated financial statements have been prepared by the Company in accordance with U.S. GAAP for interim information and pursuant to the rules and regulations of the SEC for reporting on Form 10-Q. Accordingly, certain information and footnote disclosure normally included in financial statements prepared in accordance with U.S. GAAP have been &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;condensed or omitted pursuant to such rules and regulations. These unaudited condensed interim financial statements should be read in conjunction with the audited financial statements and related notes included in the Company&#x2019;s annual report on Form 10-K for the year ended December&#160;31,&#160;2023 filed with the SEC.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The unaudited interim consolidated financial statements have been prepared on the same basis as the audited consolidated financial statements, and in management&#x2019;s opinion, include all adjustments, consisting of only normal recurring adjustments, necessary for the fair presentation of the financial information for the interim periods have been made. The results of operations for the three and nine months ended September&#160;30,&#160;2024 are not necessarily indicative of the results to be expected for the full fiscal year or any future period.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Use of estimates&lt;/b&gt;&#x2014;The preparation of financial statements in conformity with U.S.&#160;GAAP requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenue, and expenses as of and during the reporting period. The Company bases estimates and assumptions on historical experience when available and on various factors that it believes to be reasonable under the circumstances. The Company assesses estimates on an ongoing basis; however, actual results could materially differ from those estimates. Significant items subject to such estimates and assumptions, are used for, but not limited to, include stock-based compensation and accounting for research and development costs.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Foreign currency and currency translation&lt;/b&gt;&#x2014;The functional currency for Aprea Therapeutics AB is the Swedish Krona. Assets and liabilities of Aprea Therapeutics AB are translated into United States dollars at the exchange rate in effect on the balance sheet date. Operating expenses are translated at the average exchange rate in effect during the period. Unrealized translation gains and losses are recorded as a cumulative translation adjustment, which is included in the consolidated statements of stockholders&#x2019; equity as a component of accumulated other comprehensive loss. Adjustments that arise from exchange rate changes on transactions denominated in a currency other than the local currency are included in other income, net in the condensed consolidated statements of operations and comprehensive loss as incurred.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Cash and cash equivalents&#x2014; &lt;/b&gt;The Company considers all highly liquid investments with original maturities of three months or less at the date of purchase to be cash equivalents.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Restricted cash&#x2014; &lt;/b&gt;The Company has restricted cash of $41,537 and $40,717 at September&#160;30,&#160;2024 and December&#160;31,&#160;2023, respectively, that is securing the Company&#x2019;s credit card program.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Fair value of financial instruments&lt;/b&gt;&#x2014;The accounting standard for fair value measurements provides a framework for measuring fair value and requires expanded disclosures regarding fair value measurements. Fair value is defined as the price that would be received upon sale of an asset or paid to transfer a liability between market participants at measurement dates. ASC Topic 820, Fair Value Measurement (&#x201c;ASC 820&#x201d;), establishes a three-level valuation hierarchy for instruments measured at fair value. The hierarchy is based on the transparency of inputs to the valuation of an asset or liability as of the measurement date. The hierarchy defines three levels of valuation inputs, of which the first two are considered observable and the last is considered unobservable:&lt;/p&gt;&lt;table style="border-collapse:collapse;font-family:'Times New Roman','Times','serif';font-size:10pt;margin-bottom:12pt;margin-top:0pt;table-layout:fixed;width:100%;border:0pt;"&gt;&lt;tr&gt;&lt;td style="font-family:'Times New Roman','Times','serif';font-size:10pt;vertical-align:text-top;white-space:nowrap;width:18pt;padding:0pt;"&gt;&#x25cf;&lt;/td&gt;&lt;td style="padding:0pt;"&gt;&lt;span style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:normal;font-weight:normal;"&gt;Level&#160;1 inputs: Quoted prices in active markets for identical assets or liabilities.&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;table style="border-collapse:collapse;font-family:'Times New Roman','Times','serif';font-size:10pt;margin-bottom:12pt;margin-top:0pt;table-layout:fixed;width:100%;border:0pt;"&gt;&lt;tr&gt;&lt;td style="font-family:'Times New Roman','Times','serif';font-size:10pt;vertical-align:text-top;white-space:nowrap;width:18pt;padding:0pt;"&gt;&#x25cf;&lt;/td&gt;&lt;td style="padding:0pt;"&gt;&lt;span style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:normal;font-weight:normal;"&gt;Level&#160;2 inputs: Inputs other than quoted prices included within Level&#160;1 that are either directly or indirectly observable, such as quoted market prices, interest rates and yield curves.&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;table style="border-collapse:collapse;font-family:'Times New Roman','Times','serif';font-size:10pt;margin-bottom:0pt;margin-top:0pt;table-layout:fixed;width:100%;border:0pt;"&gt;&lt;tr&gt;&lt;td style="font-family:'Times New Roman','Times','serif';font-size:10pt;vertical-align:text-top;white-space:nowrap;width:18pt;padding:0pt;"&gt;&#x25cf;&lt;/td&gt;&lt;td style="padding:0pt;"&gt;&lt;span style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:normal;font-weight:normal;"&gt;Level&#160;3 inputs: Unobservable inputs developed using estimates or assumptions developed by the Company, which reflect those that a market participant would use in pricing the asset or liability.&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;div style="margin-top:12pt;"&gt;&lt;/div&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;To the extent that the valuation is based on models or inputs that are less observable or unobservable in the market, the determination of fair value requires more judgment. Accordingly, the degree of judgment exercised by the Company in &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;determining fair value is greatest for instruments categorized in Level&#160;3. A financial instrument&#x2019;s level within the fair value hierarchy is based on the lowest level of any input that is significant to the fair value measurement.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The Company&#x2019;s financial instruments consist of cash, cash equivalents, restricted cash, accounts payable and accrued expenses. The carrying amount of accounts payable and accrued expenses is considered a reasonable estimate of fair value due to the short-term maturity.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Series A Convertible Preferred Stock&lt;/b&gt;&#x2014;The Company classifies the Series A Preferred Stock as temporary equity outside of stockholders&#x2019; equity on the accompanying condensed consolidated balance sheets&#160;due to certain events that are not within the Company's control.&#160;The Series A Preferred Stock was recorded at fair value upon the acquisition of Atrin in May 2022.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Accounting for leases&lt;/b&gt;&#x2014;At the inception of an arrangement, the Company determines whether the arrangement is or contains a lease based on specific facts and circumstances, the existence of an identified asset(s), if any, and the Company&#x2019;s control over the use of the identified asset(s), if applicable. Operating lease liabilities and their corresponding right of use assets are recorded based on the present value of future lease payments over the expected lease term. The interest rate implicit in lease contracts is typically not readily determinable. As such, the Company utilizes the incremental borrowing rate, which is the rate incurred to borrow on a collateralized basis over a similar term an amount equal to the lease payments in a similar economic environment. &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;padding-bottom:12pt;margin:0pt;"&gt;The Company has elected not to separate lease and non-lease components as a single component. Operating leases are recognized on the balance sheet as right of use (ROU) lease assets, lease liabilities current and lease liabilities non-current. Fixed rents are included in the calculation of the lease balances while variable costs paid for certain operating and pass-through costs are excluded. Lease expense is recognized over the expected term on a straight-line basis. The Company has also elected the short-term lease exemption for all leases with an original term of less than 12&#160;months.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;background:#ffffff;margin:0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Research and development costs&lt;/b&gt;&#x2014;Research and development costs are charged to expense as incurred. Research and development expenses incurred in performing research and development activities, include salaries and benefits, materials and supplies, preclinical expenses, stock-based compensation expense, depreciation of equipment, contract services, and other outside expenses. Costs for certain development activities are recognized based on an evaluation of the progress to completion of specific tasks using information provided to the Company by its vendors on their actual costs incurred. Payments for these activities are based on the terms of the individual arrangements, which may differ from the pattern of costs incurred, and are reflected in the financial statements as prepaid or accrued research and development. Deposits made by the Company with certain service providers that are to be applied to future payments due under the service agreements or returned to the Company if not utilized are recorded in the consolidated balance sheets.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;background:#ffffff;margin:0pt;"&gt;&lt;span style="font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;background:#ffffff;margin:0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Revenue recognition&lt;/b&gt;&#x2014; The Company&#x2019;s revenue is primarily generated through grants from government and non-government organizations. Grant revenue is recognized during the period that the reimbursable research and development services occur, as qualifying expenses are incurred or conditions of the grants are met. Grant revenue received in advance is recorded as deferred grant revenue and recognized as revenue once the conditions for revenue recognition are met. Associated expenses are recognized when incurred as research and development expenses. The Company concluded that payments received under these grants represent conditional, nonreciprocal contributions, as described in ASC&#160;&lt;i style="font-style:italic;"&gt;958,&lt;/i&gt;&lt;i style="font-style:italic;"&gt;&#160;&lt;/i&gt;Not-for-Profit Entities, and that the grants are&#160;&lt;i style="font-style:italic;"&gt;not&lt;/i&gt;&#160;within the scope of ASC&#160;&lt;i style="font-style:italic;"&gt;606,&lt;/i&gt;&#160;Revenue from Contracts with Customers, as the organizations providing the grants do&#160;&lt;i style="font-style:italic;"&gt;not&lt;/i&gt;&#160;meet the definition of a customer. &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;background:#ffffff;margin:0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Stock-based compensation&lt;/b&gt;&#x2014;The Company measures stock options and other stock-based awards granted to employees and directors based on their fair value on the date of the grant and recognize compensation expense of those awards over the requisite service period, which is generally the vesting period of the respective award. The Company applies the straight-line method of expense recognition to all awards with only service based vesting conditions.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;For stock-based awards granted to non-employees, compensation expense is recognized over the period during which services are rendered by such non-employees until completed in accordance with ASC 718. &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The Company estimates the fair value of each stock option grant on the date of grant using the Black Scholes option pricing model, which uses as inputs the fair value of the Company&#x2019;s common stock and assumptions the Company makes for the volatility of its common stock, the expected term of its stock options, the risk-free interest rate for a period that approximates the expected term of its stock options and its expected dividend yield. The Company elects to account for forfeitures when they occur.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;The Company also awards restricted stock units (&#x201c;RSUs&#x201d;) to employees and directors. RSUs are generally subject to forfeiture if employment terminates prior to the completion of the vesting restrictions. The Company expenses the cost of the RSUs, which is determined to be the fair market value of the shares of common stock underlying the RSUs at the date of grant, ratably over the period during which the vesting restrictions lapse.&lt;span style="font-size:12pt;"&gt; &lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;span style="font-size:12pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Net loss per share&lt;/b&gt;&#x2014;The Company has reported losses since inception and has computed basic net loss per share attributable to common stockholders by dividing net loss attributable to common stockholders by the weighted-average number of common shares outstanding for the period, without consideration for potentially dilutive securities. The Company computes diluted net loss per common share after giving consideration to all potentially dilutive common shares, including options to purchase common stock, outstanding during the period determined using the treasury-stock and if-converted methods, except where the effect of including such securities would be antidilutive. Because the Company has reported net losses since inception, these potential common shares have been anti-dilutive and basic and diluted loss per share have been the same. &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;Included within weighted average common shares outstanding for the three and nine months ended September&#160;30,&#160;2024 are 507,076 common shares issuable upon the exercise of certain warrants, which are exercisable at any time for nominal consideration, and as such, the shares are considered outstanding for the purpose of calculating basic and diluted net loss per share attributable to common stockholders.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The following table sets forth the potentially dilutive securities that have been excluded from the calculation of diluted net loss per share because to include them would be anti-dilutive (in common stock equivalent shares):&lt;/p&gt;&lt;table style="border-collapse:collapse;font-size:16pt;height:max-content;margin-left:auto;margin-right:auto;padding-left:0pt;padding-right:0pt;width:80%;"&gt;&lt;tr style="height:1pt;"&gt;&lt;td style="vertical-align:bottom;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:bottom;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td colspan="3" style="vertical-align:bottom;white-space:nowrap;width:30.57%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Nine months ended September&#160;30,&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:bottom;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;&#160;&#160;&#160;&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;2024&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;&#160;&#160;&#160;&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;2023&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Convertible preferred stock (as converted)&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 28,112&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 28,112&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Options to purchase common stock&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 734,131&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 582,641&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Warrants to purchase common stock&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 2,194,788&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; &#x2014;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Unvested restricted stock units&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 36,442&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 23,870&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Total shares of common stock equivalents&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 2,993,473&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 634,623&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;span style="margin-bottom:12pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-weight:bold;margin:0pt 0pt 12pt 0pt;"&gt;Recently issued accounting pronouncements&#x2014;&lt;span style="font-weight:normal;"&gt;From time to time, new accounting pronouncements are issued by the Financial Accounting Standards Board (&#x201c;FASB&#x201d;) or other standard setting bodies that the Company adopts as of the specified effective date. &lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;In November 2023, the FASB issued ASU 2023-07, Segment Reporting (Topic 280): Improvements to Reportable Segment Disclosures. ASU 2023-07 will improve reportable segment disclosure requirements, primarily through enhanced disclosures about significant segment expenses on an interim and annual basis. The ASU is effective for fiscal years beginning after December 15, 2023, and interim periods after December 15, 2024, with early adoption permitted. The adoption of this standard is not expected to have a material impact on the Company&#x2019;s condensed financial statements at adoption date.&lt;/p&gt;</us-gaap:SignificantAccountingPoliciesTextBlock>
    <us-gaap:ConsolidationPolicyTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_XjMNNj98okKG-FrxmVh3Vw">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Principles of consolidation&lt;/b&gt;&#x2014;The consolidated financial statements include the accounts of the Company and its wholly owned subsidiaries Aprea Therapeutics AB, which was incorporated in May 2009, Aprea US,&#160;Inc., which was incorporated in June&#160;2016 and ATR Pharmaceuticals LLC which was incorporated in May 2022. Management has concluded it has a single reporting segment for purposes of reporting financial condition and results of operations. All intercompany transactions and balances have been eliminated.&lt;/p&gt;</us-gaap:ConsolidationPolicyTextBlock>
    <apre:UnauditedInterimCondensedConsolidatedFinancialStatementsPolicyTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_aC6XweIQFEalESnViFaknA">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Unaudited interim consolidated financial statements&lt;/b&gt;&#x2014;The accompanying unaudited interim condensed consolidated financial statements have been prepared by the Company in accordance with U.S. GAAP for interim information and pursuant to the rules and regulations of the SEC for reporting on Form 10-Q. Accordingly, certain information and footnote disclosure normally included in financial statements prepared in accordance with U.S. GAAP have been &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;condensed or omitted pursuant to such rules and regulations. These unaudited condensed interim financial statements should be read in conjunction with the audited financial statements and related notes included in the Company&#x2019;s annual report on Form 10-K for the year ended December&#160;31,&#160;2023 filed with the SEC.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The unaudited interim consolidated financial statements have been prepared on the same basis as the audited consolidated financial statements, and in management&#x2019;s opinion, include all adjustments, consisting of only normal recurring adjustments, necessary for the fair presentation of the financial information for the interim periods have been made. The results of operations for the three and nine months ended September&#160;30,&#160;2024 are not necessarily indicative of the results to be expected for the full fiscal year or any future period.&lt;/p&gt;</apre:UnauditedInterimCondensedConsolidatedFinancialStatementsPolicyTextBlock>
    <us-gaap:UseOfEstimates
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_vFBQmcYH-0mD_l3znCrj0g">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Use of estimates&lt;/b&gt;&#x2014;The preparation of financial statements in conformity with U.S.&#160;GAAP requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenue, and expenses as of and during the reporting period. The Company bases estimates and assumptions on historical experience when available and on various factors that it believes to be reasonable under the circumstances. The Company assesses estimates on an ongoing basis; however, actual results could materially differ from those estimates. Significant items subject to such estimates and assumptions, are used for, but not limited to, include stock-based compensation and accounting for research and development costs.&lt;/p&gt;</us-gaap:UseOfEstimates>
    <us-gaap:ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_M96s1MFyGk6iJYD7hgzl5A">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Foreign currency and currency translation&lt;/b&gt;&#x2014;The functional currency for Aprea Therapeutics AB is the Swedish Krona. Assets and liabilities of Aprea Therapeutics AB are translated into United States dollars at the exchange rate in effect on the balance sheet date. Operating expenses are translated at the average exchange rate in effect during the period. Unrealized translation gains and losses are recorded as a cumulative translation adjustment, which is included in the consolidated statements of stockholders&#x2019; equity as a component of accumulated other comprehensive loss. Adjustments that arise from exchange rate changes on transactions denominated in a currency other than the local currency are included in other income, net in the condensed consolidated statements of operations and comprehensive loss as incurred.&lt;/p&gt;</us-gaap:ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock>
    <us-gaap:CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_L73sOzHNz0230_5eTcJZgQ">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Cash and cash equivalents&#x2014; &lt;/b&gt;The Company considers all highly liquid investments with original maturities of three months or less at the date of purchase to be cash equivalents.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Restricted cash&#x2014; &lt;/b&gt;The Company has restricted cash of $41,537 and $40,717 at September&#160;30,&#160;2024 and December&#160;31,&#160;2023, respectively, that is securing the Company&#x2019;s credit card program.&lt;/p&gt;</us-gaap:CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy>
    <us-gaap:RestrictedCash
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Narr_fWqVjhkG50uqb4ZLcr9rgQ"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">41537</us-gaap:RestrictedCash>
    <us-gaap:RestrictedCash
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Narr_Qbo363oR2UquJ4T9znP7Iw"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">40717</us-gaap:RestrictedCash>
    <us-gaap:FairValueOfFinancialInstrumentsPolicy
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_yhFNXp6ewkCvQnkSJAGsgQ">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Fair value of financial instruments&lt;/b&gt;&#x2014;The accounting standard for fair value measurements provides a framework for measuring fair value and requires expanded disclosures regarding fair value measurements. Fair value is defined as the price that would be received upon sale of an asset or paid to transfer a liability between market participants at measurement dates. ASC Topic 820, Fair Value Measurement (&#x201c;ASC 820&#x201d;), establishes a three-level valuation hierarchy for instruments measured at fair value. The hierarchy is based on the transparency of inputs to the valuation of an asset or liability as of the measurement date. The hierarchy defines three levels of valuation inputs, of which the first two are considered observable and the last is considered unobservable:&lt;/p&gt;&lt;table style="border-collapse:collapse;font-family:'Times New Roman','Times','serif';font-size:10pt;margin-bottom:12pt;margin-top:0pt;table-layout:fixed;width:100%;border:0pt;"&gt;&lt;tr&gt;&lt;td style="font-family:'Times New Roman','Times','serif';font-size:10pt;vertical-align:text-top;white-space:nowrap;width:18pt;padding:0pt;"&gt;&#x25cf;&lt;/td&gt;&lt;td style="padding:0pt;"&gt;&lt;span style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:normal;font-weight:normal;"&gt;Level&#160;1 inputs: Quoted prices in active markets for identical assets or liabilities.&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;table style="border-collapse:collapse;font-family:'Times New Roman','Times','serif';font-size:10pt;margin-bottom:12pt;margin-top:0pt;table-layout:fixed;width:100%;border:0pt;"&gt;&lt;tr&gt;&lt;td style="font-family:'Times New Roman','Times','serif';font-size:10pt;vertical-align:text-top;white-space:nowrap;width:18pt;padding:0pt;"&gt;&#x25cf;&lt;/td&gt;&lt;td style="padding:0pt;"&gt;&lt;span style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:normal;font-weight:normal;"&gt;Level&#160;2 inputs: Inputs other than quoted prices included within Level&#160;1 that are either directly or indirectly observable, such as quoted market prices, interest rates and yield curves.&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;table style="border-collapse:collapse;font-family:'Times New Roman','Times','serif';font-size:10pt;margin-bottom:0pt;margin-top:0pt;table-layout:fixed;width:100%;border:0pt;"&gt;&lt;tr&gt;&lt;td style="font-family:'Times New Roman','Times','serif';font-size:10pt;vertical-align:text-top;white-space:nowrap;width:18pt;padding:0pt;"&gt;&#x25cf;&lt;/td&gt;&lt;td style="padding:0pt;"&gt;&lt;span style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:normal;font-weight:normal;"&gt;Level&#160;3 inputs: Unobservable inputs developed using estimates or assumptions developed by the Company, which reflect those that a market participant would use in pricing the asset or liability.&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;div style="margin-top:12pt;"&gt;&lt;/div&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;To the extent that the valuation is based on models or inputs that are less observable or unobservable in the market, the determination of fair value requires more judgment. Accordingly, the degree of judgment exercised by the Company in &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;determining fair value is greatest for instruments categorized in Level&#160;3. A financial instrument&#x2019;s level within the fair value hierarchy is based on the lowest level of any input that is significant to the fair value measurement.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The Company&#x2019;s financial instruments consist of cash, cash equivalents, restricted cash, accounts payable and accrued expenses. The carrying amount of accounts payable and accrued expenses is considered a reasonable estimate of fair value due to the short-term maturity.&lt;/p&gt;</us-gaap:FairValueOfFinancialInstrumentsPolicy>
    <apre:TemporaryEquityPolicyTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_Z4sTgrNbjUWp3QuFbuEz6g">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Series A Convertible Preferred Stock&lt;/b&gt;&#x2014;The Company classifies the Series A Preferred Stock as temporary equity outside of stockholders&#x2019; equity on the accompanying condensed consolidated balance sheets&#160;due to certain events that are not within the Company's control.&#160;The Series A Preferred Stock was recorded at fair value upon the acquisition of Atrin in May 2022.&lt;/p&gt;</apre:TemporaryEquityPolicyTextBlock>
    <us-gaap:LesseeLeasesPolicyTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_tXkYhFMRikGB5pdJMLjmsw">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Accounting for leases&lt;/b&gt;&#x2014;At the inception of an arrangement, the Company determines whether the arrangement is or contains a lease based on specific facts and circumstances, the existence of an identified asset(s), if any, and the Company&#x2019;s control over the use of the identified asset(s), if applicable. Operating lease liabilities and their corresponding right of use assets are recorded based on the present value of future lease payments over the expected lease term. The interest rate implicit in lease contracts is typically not readily determinable. As such, the Company utilizes the incremental borrowing rate, which is the rate incurred to borrow on a collateralized basis over a similar term an amount equal to the lease payments in a similar economic environment. &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;padding-bottom:12pt;margin:0pt;"&gt;The Company has elected not to separate lease and non-lease components as a single component. Operating leases are recognized on the balance sheet as right of use (ROU) lease assets, lease liabilities current and lease liabilities non-current. Fixed rents are included in the calculation of the lease balances while variable costs paid for certain operating and pass-through costs are excluded. Lease expense is recognized over the expected term on a straight-line basis. The Company has also elected the short-term lease exemption for all leases with an original term of less than 12&#160;months.&lt;/p&gt;</us-gaap:LesseeLeasesPolicyTextBlock>
    <us-gaap:ResearchAndDevelopmentExpensePolicy
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_lm-LuDqijkiPbw8RMSQdug">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;background:#ffffff;margin:0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Research and development costs&lt;/b&gt;&#x2014;Research and development costs are charged to expense as incurred. Research and development expenses incurred in performing research and development activities, include salaries and benefits, materials and supplies, preclinical expenses, stock-based compensation expense, depreciation of equipment, contract services, and other outside expenses. Costs for certain development activities are recognized based on an evaluation of the progress to completion of specific tasks using information provided to the Company by its vendors on their actual costs incurred. Payments for these activities are based on the terms of the individual arrangements, which may differ from the pattern of costs incurred, and are reflected in the financial statements as prepaid or accrued research and development. Deposits made by the Company with certain service providers that are to be applied to future payments due under the service agreements or returned to the Company if not utilized are recorded in the consolidated balance sheets.&lt;/p&gt;</us-gaap:ResearchAndDevelopmentExpensePolicy>
    <us-gaap:RevenueRecognitionPolicyTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_6e7awdMBe0iNuaPD1_vpOA">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;background:#ffffff;margin:0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Revenue recognition&lt;/b&gt;&#x2014; The Company&#x2019;s revenue is primarily generated through grants from government and non-government organizations. Grant revenue is recognized during the period that the reimbursable research and development services occur, as qualifying expenses are incurred or conditions of the grants are met. Grant revenue received in advance is recorded as deferred grant revenue and recognized as revenue once the conditions for revenue recognition are met. Associated expenses are recognized when incurred as research and development expenses. The Company concluded that payments received under these grants represent conditional, nonreciprocal contributions, as described in ASC&#160;&lt;i style="font-style:italic;"&gt;958,&lt;/i&gt;&lt;i style="font-style:italic;"&gt;&#160;&lt;/i&gt;Not-for-Profit Entities, and that the grants are&#160;&lt;i style="font-style:italic;"&gt;not&lt;/i&gt;&#160;within the scope of ASC&#160;&lt;i style="font-style:italic;"&gt;606,&lt;/i&gt;&#160;Revenue from Contracts with Customers, as the organizations providing the grants do&#160;&lt;i style="font-style:italic;"&gt;not&lt;/i&gt;&#160;meet the definition of a customer. &lt;/p&gt;</us-gaap:RevenueRecognitionPolicyTextBlock>
    <us-gaap:ShareBasedCompensationOptionAndIncentivePlansPolicy
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_i7F0ViNjwUaJAIef_wiDOQ">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Stock-based compensation&lt;/b&gt;&#x2014;The Company measures stock options and other stock-based awards granted to employees and directors based on their fair value on the date of the grant and recognize compensation expense of those awards over the requisite service period, which is generally the vesting period of the respective award. The Company applies the straight-line method of expense recognition to all awards with only service based vesting conditions.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;For stock-based awards granted to non-employees, compensation expense is recognized over the period during which services are rendered by such non-employees until completed in accordance with ASC 718. &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The Company estimates the fair value of each stock option grant on the date of grant using the Black Scholes option pricing model, which uses as inputs the fair value of the Company&#x2019;s common stock and assumptions the Company makes for the volatility of its common stock, the expected term of its stock options, the risk-free interest rate for a period that approximates the expected term of its stock options and its expected dividend yield. The Company elects to account for forfeitures when they occur.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;The Company also awards restricted stock units (&#x201c;RSUs&#x201d;) to employees and directors. RSUs are generally subject to forfeiture if employment terminates prior to the completion of the vesting restrictions. The Company expenses the cost of the RSUs, which is determined to be the fair market value of the shares of common stock underlying the RSUs at the date of grant, ratably over the period during which the vesting restrictions lapse.&lt;span style="font-size:12pt;"&gt; &lt;/span&gt;&lt;/p&gt;</us-gaap:ShareBasedCompensationOptionAndIncentivePlansPolicy>
    <us-gaap:EarningsPerSharePolicyTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_4sz1AHPQj02e79BwnX2c1A">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Net loss per share&lt;/b&gt;&#x2014;The Company has reported losses since inception and has computed basic net loss per share attributable to common stockholders by dividing net loss attributable to common stockholders by the weighted-average number of common shares outstanding for the period, without consideration for potentially dilutive securities. The Company computes diluted net loss per common share after giving consideration to all potentially dilutive common shares, including options to purchase common stock, outstanding during the period determined using the treasury-stock and if-converted methods, except where the effect of including such securities would be antidilutive. Because the Company has reported net losses since inception, these potential common shares have been anti-dilutive and basic and diluted loss per share have been the same. &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;Included within weighted average common shares outstanding for the three and nine months ended September&#160;30,&#160;2024 are 507,076 common shares issuable upon the exercise of certain warrants, which are exercisable at any time for nominal consideration, and as such, the shares are considered outstanding for the purpose of calculating basic and diluted net loss per share attributable to common stockholders.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The following table sets forth the potentially dilutive securities that have been excluded from the calculation of diluted net loss per share because to include them would be anti-dilutive (in common stock equivalent shares):&lt;/p&gt;&lt;table style="border-collapse:collapse;font-size:16pt;height:max-content;margin-left:auto;margin-right:auto;padding-left:0pt;padding-right:0pt;width:80%;"&gt;&lt;tr style="height:1pt;"&gt;&lt;td style="vertical-align:bottom;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:bottom;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td colspan="3" style="vertical-align:bottom;white-space:nowrap;width:30.57%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Nine months ended September&#160;30,&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:bottom;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;&#160;&#160;&#160;&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;2024&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;&#160;&#160;&#160;&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;2023&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Convertible preferred stock (as converted)&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 28,112&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 28,112&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Options to purchase common stock&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 734,131&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 582,641&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Warrants to purchase common stock&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 2,194,788&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; &#x2014;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Unvested restricted stock units&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 36,442&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 23,870&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Total shares of common stock equivalents&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 2,993,473&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 634,623&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</us-gaap:EarningsPerSharePolicyTextBlock>
    <us-gaap:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
      contextRef="As_Of_9_30_2024_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_WAR5SHVFkE6tbDGoKuqOZg"
      decimals="INF"
      id="Narr_WzzAmbQQGESkqcjHWta9AQ"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">507076</us-gaap:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights>
    <us-gaap:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
      contextRef="As_Of_9_30_2024_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_WAR5SHVFkE6tbDGoKuqOZg"
      decimals="INF"
      id="Narr_Spd-Nyl6QEmiwb8CTG_pqQ"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">507076</us-gaap:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights>
    <us-gaap:ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_A5FgWA2sNUSG2-wLVEygCA">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The following table sets forth the potentially dilutive securities that have been excluded from the calculation of diluted net loss per share because to include them would be anti-dilutive (in common stock equivalent shares):&lt;/p&gt;&lt;table style="border-collapse:collapse;font-size:16pt;height:max-content;margin-left:auto;margin-right:auto;padding-left:0pt;padding-right:0pt;width:80%;"&gt;&lt;tr style="height:1pt;"&gt;&lt;td style="vertical-align:bottom;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:bottom;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td colspan="3" style="vertical-align:bottom;white-space:nowrap;width:30.57%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;Nine months ended September&#160;30,&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:bottom;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;&#160;&#160;&#160;&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;2024&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;&#160;&#160;&#160;&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;2023&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Convertible preferred stock (as converted)&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 28,112&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 28,112&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Options to purchase common stock&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 734,131&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 582,641&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Warrants to purchase common stock&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 2,194,788&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; &#x2014;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Unvested restricted stock units&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 36,442&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 23,870&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:67.36%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Total shares of common stock equivalents&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.06%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.67%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 2,993,473&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:3.23%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:13.66%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 634,623&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</us-gaap:ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock>
    <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
      contextRef="Duration_1_1_2024_To_9_30_2024_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_ConvertiblePreferredStockMember_-xdRwU9xSUiPNwUETulTXA"
      decimals="INF"
      id="Tc_dHoO9S3DAECwCnBMMTXB5Q_3_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">28112</us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount>
    <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
      contextRef="Duration_1_1_2023_To_9_30_2023_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_ConvertiblePreferredStockMember_z_oRFQwZ_U2_FPccUncU4Q"
      decimals="INF"
      id="Tc_o140uOgmv069dOK6ee9zdQ_3_4"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">28112</us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount>
    <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
      contextRef="Duration_1_1_2024_To_9_30_2024_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_EmployeeStockOptionMember_lWBjcVjr5UKoPSricaY5kw"
      decimals="INF"
      id="Tc_EJnzFr7X3kqmucT6tZvArQ_4_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">734131</us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount>
    <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
      contextRef="Duration_1_1_2023_To_9_30_2023_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_EmployeeStockOptionMember_I-_Nu9K7KEKrfxHT-XiE6A"
      decimals="INF"
      id="Tc_EFqoR1A6_U-vWv_yDW79GQ_4_4"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">582641</us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount>
    <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
      contextRef="Duration_1_1_2024_To_9_30_2024_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_WarrantMember_18zK2B__vkKA8IrK9I5aKw"
      decimals="INF"
      id="Tc_oXG3Z3xwREOFxQ2-PiiVVg_5_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">2194788</us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount>
    <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
      contextRef="Duration_1_1_2024_To_9_30_2024_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_RestrictedStockUnitsRSUMember_BniNzMIFNESCAEERHrL4Qg"
      decimals="INF"
      id="Tc_nrY1GN7oEEu_BxDU8Kj6rw_6_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">36442</us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount>
    <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
      contextRef="Duration_1_1_2023_To_9_30_2023_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_us-gaap_RestrictedStockUnitsRSUMember_V6BVG1ivukSZDtIV_eHuyA"
      decimals="INF"
      id="Tc_I69oiOiFkUi7kZL6Ogdakw_6_4"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">23870</us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount>
    <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="INF"
      id="Tc_8gN_vzHN7U6p34LPk7lgxQ_7_2"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">2993473</us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount>
    <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="INF"
      id="Tc_SGtdBuQN8ketXUU79aHE2g_7_4"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">634623</us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount>
    <us-gaap:NewAccountingPronouncementsPolicyPolicyTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_xynWj9Ix50madTBHF8oxtg">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-weight:bold;margin:0pt 0pt 12pt 0pt;"&gt;Recently issued accounting pronouncements&#x2014;&lt;span style="font-weight:normal;"&gt;From time to time, new accounting pronouncements are issued by the Financial Accounting Standards Board (&#x201c;FASB&#x201d;) or other standard setting bodies that the Company adopts as of the specified effective date. &lt;/span&gt;&lt;/p&gt;</us-gaap:NewAccountingPronouncementsPolicyPolicyTextBlock>
    <apre:LeaseDisclosureTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_F7z5NAA9wE-bn6V8JqcErw">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-weight:bold;margin:0pt 0pt 12pt 0pt;"&gt;3. Leases&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The Company is party to one operating lease for office and laboratory space. The Company&#x2019;s finance leases are immaterial both individually and in the aggregate. The Company has elected to apply the short-term lease exception to all leases of one&#160;year or less. Rent expense for each of the three months ended September&#160;30,&#160;2024 and 2023 was $19,998. Rent expense for each of the nine months ended September&#160;30,&#160;2024 and 2023 was $59,993, which is included in operating expenses. &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;The Company has an annual operating lease for office and laboratory space in Doylestown, Pennsylvania which was amended in October 2024 and is currently set to expire on October 31, 2025. Rent expense under this lease is $110,000 annually and the Company has applied the short-term exception to this lease. The Company has &lt;span style="-sec-ix-hidden:Hidden_dXY0fqi6LUqjrBt7mcO_tw;"&gt;&lt;span style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:normal;font-weight:normal;"&gt;no&lt;/span&gt;&lt;/span&gt; lease obligations beyond October 2025.&lt;/p&gt;</apre:LeaseDisclosureTextBlock>
    <apre:LesseeOperatingLeaseNumberOfOperatingLeases
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="INF"
      id="Narr_7vN6DwcjMEOnCWtuLC2ucw"
      unitRef="Unit_Standard_lease_uug6S_kQsEij919rCVEEeQ">1</apre:LesseeOperatingLeaseNumberOfOperatingLeases>
    <us-gaap:OperatingLeaseExpense
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Narr_Whqcbb5tk0KBJ6hKx611qg"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">19998</us-gaap:OperatingLeaseExpense>
    <us-gaap:OperatingLeaseExpense
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Narr_HY4MxuLRdE-GswImWSQseA"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">19998</us-gaap:OperatingLeaseExpense>
    <us-gaap:OperatingLeaseExpense
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Narr_VWvYSTE2V0i-e_rU9Jc1kA"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">59993</us-gaap:OperatingLeaseExpense>
    <us-gaap:OperatingLeaseExpense
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Narr_Elt3eS_utEK_FEpLO9T9kw"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">59993</us-gaap:OperatingLeaseExpense>
    <apre:LesseeOperatingLeaseAnnualBaseRent
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="INF"
      id="Narr_3zlvYhneYkWYPGssS7s8GA"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">110000</apre:LesseeOperatingLeaseAnnualBaseRent>
    <us-gaap:AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_7eXRpuTclUSB76UXwctvbQ">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-weight:bold;margin:0pt 0pt 10pt 0pt;"&gt;4. Accrued expenses&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 10pt 0pt;"&gt;Accrued expenses consist of the following:&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;min-height:0.0pt;margin:0pt;"&gt;&lt;span style="font-size:0pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;table style="border-collapse:collapse;font-size:16pt;height:max-content;margin-left:auto;margin-right:auto;padding-left:0pt;padding-right:0pt;width:100%;"&gt;&lt;tr style="height:1pt;"&gt;&lt;td style="vertical-align:top;width:72.55%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="position:absolute;top:0pt;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:bottom;width:72.55%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;&#160;&#160;&#160;&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td colspan="2" style="vertical-align:bottom;white-space:nowrap;width:11.38%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;September&#160;30,&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;&#160;&#160;&#160;&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td colspan="2" style="vertical-align:bottom;white-space:nowrap;width:11.38%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;December&#160;31,&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:bottom;width:72.55%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td colspan="2" style="vertical-align:bottom;white-space:nowrap;width:11.38%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;2024&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td colspan="2" style="vertical-align:bottom;white-space:nowrap;width:11.38%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;2023&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:72.55%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Professional&#160;fees&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;$&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 168,225&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;$&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 138,601&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:72.55%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Compensation, severance&#160;and&#160;benefits&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 673,322&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 1,016,960&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:72.55%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Research&#160;and&#160;development&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 1,582,173&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 856,575&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:72.55%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Other&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 58,288&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 174,126&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:72.55%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 12pt;"&gt;Total&#160;accrued&#160;expenses&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;$&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 2,482,008&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;$&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 2,186,262&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;span style="font-size:1pt;margin-bottom:12pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;</us-gaap:AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock>
    <us-gaap:ScheduleOfAccruedLiabilitiesTableTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_TwTWdpTvXUuVN41oDaz6HQ">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;min-height:0.0pt;margin:0pt;"&gt;&lt;span style="font-size:0pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;table style="border-collapse:collapse;font-size:16pt;height:max-content;margin-left:auto;margin-right:auto;padding-left:0pt;padding-right:0pt;width:100%;"&gt;&lt;tr style="height:1pt;"&gt;&lt;td style="vertical-align:top;width:72.55%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="position:absolute;top:0pt;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;margin:0pt;padding:0pt;"&gt;&lt;div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"&gt;&lt;div style="bottom:0pt;position:absolute;width:100%;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:1pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:bottom;width:72.55%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;&#160;&#160;&#160;&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td colspan="2" style="vertical-align:bottom;white-space:nowrap;width:11.38%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;September&#160;30,&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;&#160;&#160;&#160;&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td colspan="2" style="vertical-align:bottom;white-space:nowrap;width:11.38%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;December&#160;31,&#160;&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:bottom;width:72.55%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td colspan="2" style="vertical-align:bottom;white-space:nowrap;width:11.38%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;2024&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="font-size:8pt;font-weight:bold;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td colspan="2" style="vertical-align:bottom;white-space:nowrap;width:11.38%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:8pt;text-align:center;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;2023&lt;/b&gt;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:72.55%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Professional&#160;fees&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;$&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 168,225&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;$&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 138,601&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:72.55%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Compensation, severance&#160;and&#160;benefits&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 673,322&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 1,016,960&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:72.55%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Research&#160;and&#160;development&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 1,582,173&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 856,575&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:72.55%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;Other&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 58,288&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&#160;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 174,126&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style="vertical-align:top;width:72.55%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 12pt;"&gt;Total&#160;accrued&#160;expenses&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;$&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 2,482,008&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:2.33%;background:#cceeff;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:1.5%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 0.05pt 0pt;"&gt;$&lt;/p&gt;&lt;/td&gt;&lt;td style="vertical-align:bottom;white-space:nowrap;width:9.88%;background:#cceeff;border-bottom:3px double #000000;margin:0pt;padding:0pt;"&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:right;margin:0pt 3.5pt 0.05pt 0pt;"&gt; 2,186,262&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;span style="font-size:1pt;margin-bottom:12pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;</us-gaap:ScheduleOfAccruedLiabilitiesTableTextBlock>
    <us-gaap:AccruedProfessionalFeesCurrent
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_fM_CVDb7rEy1tSk0OnYIbA_3_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">168225</us-gaap:AccruedProfessionalFeesCurrent>
    <us-gaap:AccruedProfessionalFeesCurrent
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_Ylr8QPMDZEGCIte88zu-rQ_3_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">138601</us-gaap:AccruedProfessionalFeesCurrent>
    <us-gaap:EmployeeRelatedLiabilitiesCurrent
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_4Jg9WbXbDkeSRmVoe68acg_4_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">673322</us-gaap:EmployeeRelatedLiabilitiesCurrent>
    <us-gaap:EmployeeRelatedLiabilitiesCurrent
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_9eGEWAt5PUS6HynRPdoCZg_4_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1016960</us-gaap:EmployeeRelatedLiabilitiesCurrent>
    <apre:ResearchAndDevelopmentRelatedLiabilitiesCurrent
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_mHNN4GwhSUu5HhEZBFEAOg_5_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1582173</apre:ResearchAndDevelopmentRelatedLiabilitiesCurrent>
    <apre:ResearchAndDevelopmentRelatedLiabilitiesCurrent
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_97GjH06PP0eOzkF486ilYA_5_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">856575</apre:ResearchAndDevelopmentRelatedLiabilitiesCurrent>
    <us-gaap:OtherAccruedLiabilitiesCurrent
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_dd9dHVwueECnV8Aq34xfJw_6_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">58288</us-gaap:OtherAccruedLiabilitiesCurrent>
    <us-gaap:OtherAccruedLiabilitiesCurrent
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_AOpvp2KcPkactpQuCCiNmg_6_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">174126</us-gaap:OtherAccruedLiabilitiesCurrent>
    <apre:AccruedLiabilitiesAndEmployeeRelatedLiabilitiesCurrent
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="0"
      id="Tc_HyqeikMXYUaB-pwOnNQvfA_7_3"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">2482008</apre:AccruedLiabilitiesAndEmployeeRelatedLiabilitiesCurrent>
    <apre:AccruedLiabilitiesAndEmployeeRelatedLiabilitiesCurrent
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="0"
      id="Tc_trDCJsT1yUmhOicnSSKvRg_7_6"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">2186262</apre:AccruedLiabilitiesAndEmployeeRelatedLiabilitiesCurrent>
    <apre:CommonStockTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_vmWvwuyPH0ONwH5iVSZSTA">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-weight:bold;margin:0pt 0pt 10pt 0pt;"&gt;5. Stockholders&#x2019; equity &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;The total number of shares of all classes of capital stock that the Company is authorized to issue is 440,000,000 shares, consisting of 400,000,000 shares of common stock, par value $0.001 per share and 40,000,000 shares of preferred stock, par value $0.001 per share.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;i style="font-style:italic;"&gt;Series A Preferred Stock&lt;/i&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;As of September&#160;30,&#160;2024, a total of 56,227 shares of Series A Preferred Stock remained outstanding, which are convertible into 28,112 shares of common stock.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-weight:bold;margin:0pt 0pt 10pt 0pt;"&gt;&lt;i style="font-style:italic;font-weight:normal;"&gt;Common Stock&lt;/i&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 10pt 0pt;"&gt;The holders of common stock are entitled to one&lt;span style="white-space:pre-wrap;"&gt; vote for each share of common stock.  In the event of any voluntary or involuntary liquidation, dissolution or winding up of the Company, after the payment or provision for payment of all debts and liabilities of the Company, the holders of common stock shall be entitled to share in the remaining assets of the Company available for distribution, if any.&lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 10pt 0pt;"&gt;&lt;i style="font-style:italic;"&gt;Shelf Registration Statement&lt;/i&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;On November 12, 2020, the Company filed a universal shelf registration statement with the SEC for the issuance of common stock, preferred stock, warrants, rights, debt securities and units up to an aggregate of $350.0 million (the &#x201c;2020 Shelf Registration Statement&#x201d;). On November 30, 2020, the 2020 Shelf Registration Statement was declared effective by the SEC and on November 30, 2023, the 2020 Shelf Registration Statement expired. The 2020 Shelf Registration Statement included an at-the-market offering program with SVB Leerink LLC (the &#x201c;SVB ATM Program&#x201d;) and the Company filed a Prospectus Supplement dated September 2, 2022, for the sale of up to $14,744,728 of shares of the Company&#x2019;s common stock pursuant to its ATM offering program. The Company agreed to pay a commission of 3% &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 10pt 0pt;"&gt;of the gross proceeds of any common stock sold in connection with the SVB ATM Program. During the nine months ended September&#160;30,&#160;2023, the Company issued and sold 26,302 shares of common stock under the ATM offering program resulting in net proceeds to the Company of approximately $0.3 million after deducting approximately $8,000 in issuance costs. The SVB ATM Program has terminated and is no longer effective.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 10pt 0pt;"&gt;In February 2023, the Company issued and sold 1,050,000 shares of common stock at a public offering price of $5.25 per share pursuant to the 2020 Shelf Registration Statement resulting in net proceeds to the Company of approximately $4.9 million, after deducting underwriting discounts and offering expenses of approximately $0.6 million. &lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 10pt 0pt;"&gt;On January 26, 2024, the Company filed a new shelf registration statement (the &#x201c;2024 Shelf Registration Statement&#x201d;) with the SEC for issuance of common stock, preferred stock, warrants, rights, debt securities and units up to an aggregate of $150 million, including a prospectus for the sale of $1&lt;span style="white-space:pre-wrap;"&gt; million of shares of our common stock under the ATM Agreement, as defined below, which was declared effective on February 2, 2024.  The Company subsequently filed a prospectus supplement to the 2024 Shelf Registration Statement for the sale of up to &lt;/span&gt;$2&lt;span style="white-space:pre-wrap;"&gt; million of shares of common stock pursuant to the ATM Agreement.  On January 26, 2024, the Company entered into an At the Market Offering Agreement (the &#x201c;ATM Agreement&#x201d;) with H.C. Wainwright &amp;amp; Co., LLC (&#x201c;HCW&#x201d;).  Pursuant to the ATM Agreement and the prospectus supplement filed in connection therewith, the Company was able, from time to time, in its sole discretion, to issue and sell through HCW, acting as sales agent and/or principal, up to &lt;/span&gt;$2&lt;span style="white-space:pre-wrap;"&gt; million of shares of common stock.  The Company did not make any sales under the ATM Agreement and in March 2024, the Company terminated the ATM Agreement with HCW.&lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;&lt;i style="font-style:italic;"&gt;March 2024 Private Placement&lt;/i&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 10pt 0pt;"&gt;On March 11, 2024, the Company entered into a securities purchase agreement with certain purchasers (the &#x201c;Purchasers&#x201d;) pursuant to which the Company agreed to issue and sell to the Purchasers in a private placement offering exempt from registration under the Securities Act of 1933, as amended, or the Securities Act, and the Purchasers agreed to purchase from the Company (i) 1,687,712 shares of the Company&#x2019;s common stock at a purchase price of $7.29 per share (the &#x201c;Shares&#x201d;), (ii) pre-funded common stock purchase warrants at a purchase price of $7.289 to purchase an aggregate of up to 507,076 shares of the Company&#x2019;s common stock at an exercise price of $0.001 per share (the &#x201c;Pre-Funded Shares&#x201d;), (iii) tranche A common stock purchase warrants to purchase up to 1,097,394 shares of the Company&#x2019;s common stock at an exercise price of $7.29 per share (the &#x201c;Tranche A Warrants&#x201d;), and (iv) tranche B common stock purchase warrants to purchase up to 1,097,394 shares of the Company&#x2019;s common stock at an exercise price of $9.1125 per share (the &#x201c;Tranche B Warrants&#x201d;). The Tranche A Warrants will be exercisable until the earlier of (i) the three-year anniversary of issuance and (ii) 30 days after the Company announces the recommended Phase 2 dose for ATRN-119, and, following such announcement, the daily volume weighted average price of the Company&#x2019;s common stock equals or exceeds $14.58 for 30 consecutive trading days. The Tranche B Warrants will be exercisable until the earlier of (i) the five-year anniversary of issuance and (ii) 30 days after the Company announces the recommended Phase 2 dose for APR-1051 and, following such announcement, the daily volume weighted average price of the Company&#x2019;s common stock equals or exceeds $18.225 for 30 consecutive trading days. To the extent that the exercise of a Tranche A Warrant or Tranche B Warrant would result in the holder beneficially owning greater than 4.99% (or, at the election of the holder, greater than 9.99%) of the Company&#x2019;s outstanding common stock immediately following such exercise, the holder will instead receive pre-funded warrants in substantially the same form as the pre-funded warrants issued at closing. The aggregate upfront gross proceeds from the issuance of common stock and pre-funded common stock purchase warrants totaled approximately $16.0 million, before deducting placement agent fees and offering costs of approximately $1.3 million. The gross proceeds from potential future warrant cash exercises are expected to be up to approximately $18.0 million, before deducting placement agent fees. In April 2024, we registered on Form S-3 the resale of the Shares, the Pre-Funded Shares and the shares underlying the Tranche A Warrants and Tranche B Warrants.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 10pt 0pt;"&gt;The Company evaluated the terms of the warrants issued and determined that they should be classified as equity instruments within additional paid-in capital. As of September&#160;30,&#160;2024, none of the pre-funded warrants, Tranche A Warrants or Tranche B Warrants have been exercised.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 10pt 0pt;"&gt;&lt;i style="font-style:italic;"&gt;Stock-Based Compensation Expense&lt;/i&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;The Company recorded stock-based compensation expense of $149,090 and $76,031 for the three months ended September&#160;30,&#160;2024 and 2023, respectively. The Company recorded stock-based compensation expense of $363,408 and $361,598 for the nine months ended September&#160;30,&#160;2024 and 2023, respectively.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;span style="margin-bottom:12pt;visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;</apre:CommonStockTextBlock>
    <apre:StockSharesAuthorized
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="INF"
      id="Narr_QZu8urIr0EKJ73whMmVbWQ"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">440000000</apre:StockSharesAuthorized>
    <us-gaap:CommonStockSharesAuthorized
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="INF"
      id="Narr_vWWwbpaaskOTtXoi4trUVQ"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">400000000</us-gaap:CommonStockSharesAuthorized>
    <us-gaap:CommonStockParOrStatedValuePerShare
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="INF"
      id="Narr_8g71vJPrp0yKNCir8EBPOA"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">0.001</us-gaap:CommonStockParOrStatedValuePerShare>
    <us-gaap:PreferredStockSharesAuthorized
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="INF"
      id="Narr_0VZTxjGcAEafGLd55Aa7RQ"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">40000000</us-gaap:PreferredStockSharesAuthorized>
    <us-gaap:PreferredStockParOrStatedValuePerShare
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="INF"
      id="Narr_p_ZjpFsgdkK5t5w5imxgZQ"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">0.001</us-gaap:PreferredStockParOrStatedValuePerShare>
    <us-gaap:TemporaryEquitySharesOutstanding
      contextRef="As_Of_9_30_2024_us-gaap_StatementClassOfStockAxis_apre_ConvertiblePreferredStockSeriesaMember_vRazHx54bUee8EgCl6bZxg"
      decimals="INF"
      id="Narr_KtspceqDQUm0dDTGuRkVwQ"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">56227</us-gaap:TemporaryEquitySharesOutstanding>
    <us-gaap:PreferredStockConvertibleSharesIssuable
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="INF"
      id="Narr_snotvY5h1ku8ujGfCZdjkg"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">28112</us-gaap:PreferredStockConvertibleSharesIssuable>
    <apre:CommonStockNumberOfVotingRightsPerShare
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="INF"
      id="Narr_cvQRoMHp8UyckKt0jJx4KA"
      unitRef="Unit_Standard_Vote_xLAtZ3mDNEadoQnTSpr_cQ">1</apre:CommonStockNumberOfVotingRightsPerShare>
    <apre:UniversalShelfRegistrationMaximumAmountToBeIssued
      contextRef="As_Of_11_12_2020_us-gaap_SubsidiarySaleOfStockAxis_apre_ShelfRegistrationStatementMember_ARwQ47H460ieVrWA3BWUnQ"
      decimals="-5"
      id="Narr_sn82W6G5wk6A1GjKXlNT3w"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">350000000.0</apre:UniversalShelfRegistrationMaximumAmountToBeIssued>
    <apre:AtMarketOfferingProgramMaximumAmountToBeIssued
      contextRef="As_Of_11_12_2020_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_gmVaaYo2B0i-Fejiwesclg"
      decimals="INF"
      id="Narr_1ZfIWiluHEu6pMHUQ5eB_w"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">14744728</apre:AtMarketOfferingProgramMaximumAmountToBeIssued>
    <apre:AtMarketOfferingCommissionPayableAsPercentageOfGrossProceedsFromSaleOfCommonStock
      contextRef="Duration_11_12_2020_To_11_12_2020_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_MJWqDGoHuUiO0gnEMhlZUg"
      decimals="2"
      id="Narr_yLVhCbvlWUayp8flg4Digg"
      unitRef="Unit_Standard_pure_psC0V7jouEy1pdZ9EBR0Hw">0.03</apre:AtMarketOfferingCommissionPayableAsPercentageOfGrossProceedsFromSaleOfCommonStock>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="Duration_1_1_2023_To_9_30_2023_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_fSqftKDYcEGIBNux4uAuoQ"
      decimals="INF"
      id="Narr_b0paR4ld40ilt31kP6SzFA"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">26302</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:SaleOfStockConsiderationReceivedOnTransaction
      contextRef="Duration_1_1_2023_To_9_30_2023_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_fSqftKDYcEGIBNux4uAuoQ"
      decimals="-5"
      id="Narr_imHQ-IOC_0mefw3cDDrwug"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">300000</us-gaap:SaleOfStockConsiderationReceivedOnTransaction>
    <us-gaap:PaymentsOfStockIssuanceCosts
      contextRef="Duration_1_1_2023_To_9_30_2023_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarketOfferingMember_fSqftKDYcEGIBNux4uAuoQ"
      decimals="0"
      id="Narr_0qKLOh0FtU6_6MENb7UI1Q"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">8000</us-gaap:PaymentsOfStockIssuanceCosts>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="Duration_2_1_2023_To_2_28_2023_us-gaap_StatementClassOfStockAxis_us-gaap_CommonStockMember_us-gaap_SubsidiarySaleOfStockAxis_apre_ShelfRegistrationStatementMember_LaEYUb2hjkW2KGU-74xlQw"
      decimals="INF"
      id="Narr_ZSDuAEh0REmQHqLohaG8Mw"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">1050000</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:SaleOfStockPricePerShare
      contextRef="As_Of_2_28_2023_us-gaap_StatementClassOfStockAxis_us-gaap_CommonStockMember_us-gaap_SubsidiarySaleOfStockAxis_apre_ShelfRegistrationStatementMember_UBxEuMVTak-jJ5nG9mM16A"
      decimals="INF"
      id="Narr_qBB9itCmnEuwYlzcsSU3nw"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">5.25</us-gaap:SaleOfStockPricePerShare>
    <us-gaap:ProceedsFromIssuanceOfCommonStock
      contextRef="Duration_2_1_2023_To_2_28_2023_us-gaap_StatementClassOfStockAxis_us-gaap_CommonStockMember_us-gaap_SubsidiarySaleOfStockAxis_apre_ShelfRegistrationStatementMember_LaEYUb2hjkW2KGU-74xlQw"
      decimals="-5"
      id="Narr_U_HoenttBk61_BfGqwFoRA"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">4900000</us-gaap:ProceedsFromIssuanceOfCommonStock>
    <us-gaap:PaymentsOfStockIssuanceCosts
      contextRef="Duration_2_1_2023_To_2_28_2023_us-gaap_StatementClassOfStockAxis_us-gaap_CommonStockMember_us-gaap_SubsidiarySaleOfStockAxis_apre_ShelfRegistrationStatementMember_LaEYUb2hjkW2KGU-74xlQw"
      decimals="-5"
      id="Narr_RFTZsCEQwUy89T7mDosMVw"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">600000</us-gaap:PaymentsOfStockIssuanceCosts>
    <apre:UniversalShelfRegistrationMaximumAmountToBeIssued
      contextRef="As_Of_1_26_2024_us-gaap_SubsidiarySaleOfStockAxis_apre_ShelfRegistrationStatement2024Member_hof9NYm7h0ub2MpXywHosA"
      decimals="-6"
      id="Narr_sBAc6OcYNE6jYYAH-E1Lpw"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">150000000</apre:UniversalShelfRegistrationMaximumAmountToBeIssued>
    <apre:AtMarketOfferingProgramMaximumAmountToBeIssued
      contextRef="As_Of_1_26_2024_us-gaap_SubsidiarySaleOfStockAxis_apre_ShelfRegistrationStatement2024Member_hof9NYm7h0ub2MpXywHosA"
      decimals="-6"
      id="Narr_lsBrLnDOcEqQ1yP5-if3QQ"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1000000</apre:AtMarketOfferingProgramMaximumAmountToBeIssued>
    <apre:AtMarketOfferingProgramMaximumAmountToBeIssuedSupplement
      contextRef="As_Of_1_26_2024_us-gaap_SubsidiarySaleOfStockAxis_apre_ShelfRegistrationStatement2024Member_hof9NYm7h0ub2MpXywHosA"
      decimals="-6"
      id="Narr_c-Tt8ZOo8kmqoQWYAjmGrw"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">2000000</apre:AtMarketOfferingProgramMaximumAmountToBeIssuedSupplement>
    <apre:AtMarketOfferingProgramMaximumAmountToBeIssued
      contextRef="As_Of_1_26_2024_srt_CounterpartyNameAxis_apre_HCWainrightCoLlcMember_us-gaap_SubsidiarySaleOfStockAxis_apre_AtMarket2024OfferingMember_M05-gKo8P0qhKNNnCJ2ynA"
      decimals="-6"
      id="Narr_XASu58PP4kyxjQqTBSzJHg"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">2000000</apre:AtMarketOfferingProgramMaximumAmountToBeIssued>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="Duration_3_11_2024_To_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_NhXjTaJGO0qzpt50WX1aQA"
      decimals="INF"
      id="Narr_4wFMh3Hm2UygYmc1PEXfqg"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">1687712</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:SharesIssuedPricePerShare
      contextRef="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_5KoUULH39EatBTbigzb7Nw"
      decimals="2"
      id="Narr_Yp2Mt13lBEyYGrKXOdKJ6w"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">7.29</us-gaap:SharesIssuedPricePerShare>
    <us-gaap:SharesIssuedPricePerShare
      contextRef="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_Do28_zwKEkmVihgrJpKe5A"
      decimals="INF"
      id="Narr_AZ5Dpst84UWfBana4ROO-w"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">7.289</us-gaap:SharesIssuedPricePerShare>
    <us-gaap:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
      contextRef="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_Do28_zwKEkmVihgrJpKe5A"
      decimals="INF"
      id="Narr_lx37ipP1b02rqdR6Z8INuQ"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">507076</us-gaap:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights>
    <us-gaap:ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
      contextRef="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_5KoUULH39EatBTbigzb7Nw"
      decimals="3"
      id="Narr_72NJDpCz7USaaz6wsBzS9g"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">0.001</us-gaap:ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1>
    <us-gaap:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
      contextRef="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice7.29PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_lx_pDgysWkWXlV3jLs59hg"
      decimals="INF"
      id="Narr_RAohUyRidUKVs6iN0m9iYQ"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">1097394</us-gaap:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights>
    <us-gaap:ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
      contextRef="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice7.29PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_lx_pDgysWkWXlV3jLs59hg"
      decimals="2"
      id="Narr_X7wiODn4hk2MZSWCnVKRoA"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">7.29</us-gaap:ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1>
    <us-gaap:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
      contextRef="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice7.29PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_lx_pDgysWkWXlV3jLs59hg"
      decimals="INF"
      id="Narr_kQePR8Xab0q-qctPB6rCoQ"
      unitRef="Unit_Standard_shares_sSDE7Woa5kmBB7-iZ39Wcg">1097394</us-gaap:ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights>
    <us-gaap:ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
      contextRef="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice9.1125PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_G-a6RTBX2E2Sy0VISZQI2A"
      decimals="4"
      id="Narr_AgXIBW9IcEaeX1oG-9R8rA"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">9.1125</us-gaap:ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1>
    <apre:StockIssuanceAnniversaryPeriod
      contextRef="Duration_3_11_2024_To_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice7.29PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_2erKOwIbbU-vg-0HBwM-Ew"
      id="Narr_NIqIXRlCR0i6UddLUmfLIw">P3Y</apre:StockIssuanceAnniversaryPeriod>
    <apre:NumberOfDaysAfterCompanyAnnouncesRecommendedPhase2DoseForAtrn119
      contextRef="Duration_3_11_2024_To_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice7.29PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_2erKOwIbbU-vg-0HBwM-Ew"
      id="Narr_VtxT4GNeg02rOqDHIebX5g">P30D</apre:NumberOfDaysAfterCompanyAnnouncesRecommendedPhase2DoseForAtrn119>
    <apre:SharesIssuedVolumeWeightedAveragePricePerShare
      contextRef="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice7.29PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_lx_pDgysWkWXlV3jLs59hg"
      decimals="2"
      id="Narr_jsDtz-sRGEOwaEsCBMo4xA"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">14.58</apre:SharesIssuedVolumeWeightedAveragePricePerShare>
    <apre:NumberOfConsecutiveTradingDays
      contextRef="Duration_3_11_2024_To_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice7.29PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_2erKOwIbbU-vg-0HBwM-Ew"
      id="Narr_A7s7oYjDF0KbKhhYrIfc-w">P30D</apre:NumberOfConsecutiveTradingDays>
    <apre:StockIssuanceAnniversaryPeriod
      contextRef="Duration_3_11_2024_To_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice9.1125PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_zOEchtkouU6yqqanDoFo6w"
      id="Narr_DkqjriLx8k6iqOz3dgG4Dg">P5Y</apre:StockIssuanceAnniversaryPeriod>
    <apre:NumberOfDaysAfterCompanyAnnouncesRecommendedPhase2DoseForAtrn119
      contextRef="Duration_3_11_2024_To_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice9.1125PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_zOEchtkouU6yqqanDoFo6w"
      id="Narr_vtgg1lGcikipppKDmlc6JQ">P30D</apre:NumberOfDaysAfterCompanyAnnouncesRecommendedPhase2DoseForAtrn119>
    <apre:SharesIssuedVolumeWeightedAveragePricePerShare
      contextRef="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice9.1125PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_G-a6RTBX2E2Sy0VISZQI2A"
      decimals="3"
      id="Narr_lFPeZfyx7kSjJnvGa89kJA"
      unitRef="Unit_Divide_USD_shares_jFtjfubESUepDXxJCjGa7A">18.225</apre:SharesIssuedVolumeWeightedAveragePricePerShare>
    <apre:NumberOfConsecutiveTradingDays
      contextRef="Duration_3_11_2024_To_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_ClassOfWarrantOrRightAxis_apre_PreFundedWarrantsExercisePrice7.29PerShareMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_2erKOwIbbU-vg-0HBwM-Ew"
      id="Narr_9vckXgciA0mQLpDGZlttAg">P30D</apre:NumberOfConsecutiveTradingDays>
    <apre:PercentageOfOutstandingShares
      contextRef="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_5KoUULH39EatBTbigzb7Nw"
      decimals="4"
      id="Narr_Kjbh-J4pRkulaOG2Dy-fJg"
      unitRef="Unit_Standard_pure_psC0V7jouEy1pdZ9EBR0Hw">0.0499</apre:PercentageOfOutstandingShares>
    <apre:PercentageOfOutstandingShares
      contextRef="As_Of_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_srt_StatementScenarioAxis_apre_AtEventOfElectionOfHolderMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_jryn2JxtuUiScam-ie0pMg"
      decimals="4"
      id="Narr_Pu_2GbairkqlQHmRuKKjfQ"
      unitRef="Unit_Standard_pure_psC0V7jouEy1pdZ9EBR0Hw">0.0999</apre:PercentageOfOutstandingShares>
    <us-gaap:ProceedsFromIssuanceOrSaleOfEquity
      contextRef="Duration_3_11_2024_To_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_NhXjTaJGO0qzpt50WX1aQA"
      decimals="-5"
      id="Narr_eZPhhR4d6ESEXBadaj8FfA"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">16000000.0</us-gaap:ProceedsFromIssuanceOrSaleOfEquity>
    <us-gaap:PaymentsOfStockIssuanceCosts
      contextRef="Duration_3_11_2024_To_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_NhXjTaJGO0qzpt50WX1aQA"
      decimals="-5"
      id="Narr_OYO4Wf_YGk-fw3yvMsEY7w"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">1300000</us-gaap:PaymentsOfStockIssuanceCosts>
    <apre:ExpectedGrossProceedsFromPotentialFutureWarrantCashExercise
      contextRef="Duration_3_11_2024_To_3_11_2024_srt_CounterpartyNameAxis_apre_CertainPurchasersMember_us-gaap_SubsidiarySaleOfStockAxis_us-gaap_PrivatePlacementMember_us-gaap_TypeOfArrangementAxis_apre_SecuritiesPurchaseAgreementMember_NhXjTaJGO0qzpt50WX1aQA"
      decimals="-5"
      id="Narr_acup2Ik8kUWCtIzB_WGojg"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">18000000.0</apre:ExpectedGrossProceedsFromPotentialFutureWarrantCashExercise>
    <us-gaap:ProceedsFromWarrantExercises
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Narr_I1JD4_la00-3mgUZfCT_sQ"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">0</us-gaap:ProceedsFromWarrantExercises>
    <us-gaap:AllocatedShareBasedCompensationExpense
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="0"
      id="Narr_f_VG65IQw0SMk3rq4pDEGw"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">149090</us-gaap:AllocatedShareBasedCompensationExpense>
    <us-gaap:AllocatedShareBasedCompensationExpense
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="0"
      id="Narr_nHJyNfPc20a4o26OgXbB4g"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">76031</us-gaap:AllocatedShareBasedCompensationExpense>
    <us-gaap:AllocatedShareBasedCompensationExpense
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Narr_Fn9k7rW7XEC5fB1GMDzHxg"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">363408</us-gaap:AllocatedShareBasedCompensationExpense>
    <us-gaap:AllocatedShareBasedCompensationExpense
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="0"
      id="Narr_gTjEYJTPVkOZQkvXavuVlQ"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">361598</us-gaap:AllocatedShareBasedCompensationExpense>
    <us-gaap:IncomeTaxDisclosureTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_sHCYOpUYgU2woPy89oquTQ">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;b style="font-weight:bold;"&gt;6. Income Taxes&lt;/b&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The Company has no income tax expense due to operating losses incurred for the three and nine months ended September&#160;30,&#160;2024 and 2023. The Company has provided a valuation allowance for the full amount of the net deferred tax assets as, based on all available evidence, it is considered more likely than not that all the recorded deferred tax assets will not be realized in a future period.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;span style="white-space:pre-wrap;"&gt;Realization of the future tax benefits is dependent on may factors, including the Company&#x2019;s ability to generate taxable income within the net operating loss carryforward period.  Under the provisions of the U.S. Internal Revenue Code and Sweden tax law, certain substantial changes in the Company&#x2019;s ownership, including a sale of the Company or significant changes in ownership due to sales of equity, may have limited, or may limit in the future, the amount of net operating loss carryforwards that could be used annually to offset future taxable income.  For U.S. and Swedish income tax purposes, the Company has not completed a study to assess whether a change of control has occurred or whether there have been changes of control since the Company&#x2019;s formation due to the complexity and cost associated with such study and because there could be additional changes of control in the future.  As a result, the Company is not able to estimate the effect of the change in control, if any, on the Company&#x2019;s ability to utilize U.S. or Swedish net operating losses or other tax attribute carryforwards in the future.  For Swedish income tax purposes, the Company&#x2019;s net operating losses may be subject to limitations in accordance with the country&#x2019;s group contribution restriction laws.&lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;&lt;span style="visibility:hidden;"&gt;&#x200b;&lt;/span&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;The Company files tax returns in Sweden, the United States, Massachusetts and Pennsylvania. Income tax returns prior to 2020 in the United States and Massachusetts are no longer subject to examination and income tax returns prior to 2017 are no longer subject to examination in Sweden. The Company is not currently under examination by the IRS or any other jurisdictions for any tax years.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;As tax law is complex and often subject to varied interpretations, it is uncertain whether some of the Company&#x2019;s tax positions will be sustained upon examination. Tax liabilities associated with uncertain tax positions represent unrecognized tax benefits, which arise when the estimated benefit recorded in the Company&#x2019;s financial statements differs from the amounts taken or expected to be taken in a tax return because of the uncertainties described above. Substantially all of these unrecognized tax benefits, if recognized, would benefit the Company&#x2019;s effective income tax rate.&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 12pt 0pt;"&gt;As of September&#160;30,&#160;2024 and December&#160;31,&#160;2023, the Company had approximately $0.1 million of liabilities related to uncertain tax positions. As the Company&#x2019;s uncertain tax positions can be offset by available net operating losses, the Company did not recognize interest and penalties for 2024 and 2023.&lt;/p&gt;</us-gaap:IncomeTaxDisclosureTextBlock>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="Duration_1_1_2023_To_9_30_2023_k8UUUYOybEqporASv5v9wA"
      decimals="-6"
      id="Narr_KnJrh0lZN0KcN0pU3Q4VNQ"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">0</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="Duration_7_1_2023_To_9_30_2023_v-LjngAKfEy_IbC8lBSzug"
      decimals="-6"
      id="Narr_C769ns_V-EqYxrvi4Y2_Pg"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">0</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="-6"
      id="Narr_v6TxUCPxwkaqej36HDME1Q"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">0</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="Duration_7_1_2024_To_9_30_2024_6517Mi394ES2VFIg34L93g"
      decimals="-6"
      id="Narr_ceYO5sEWcEW_VYwb9WNYQw"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">0</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:LiabilityForUncertainTaxPositionsNoncurrent
      contextRef="As_Of_9_30_2024_B-SqioY7F0Cr4CUP1IEowQ"
      decimals="-5"
      id="Narr_2QEUnkXDnUyMdKnyJ8zKKQ"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">100000</us-gaap:LiabilityForUncertainTaxPositionsNoncurrent>
    <us-gaap:LiabilityForUncertainTaxPositionsNoncurrent
      contextRef="As_Of_12_31_2023_agvJLElEFkGptfHsxeyYBg"
      decimals="-5"
      id="Narr_5i_WbmqNC0OS_71tYUhsNg"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">100000</us-gaap:LiabilityForUncertainTaxPositionsNoncurrent>
    <us-gaap:CommitmentsAndContingenciesDisclosureTextBlock
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      id="Tb_6XdxMGekK0eoUYSC-W2INw">&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 10pt 0pt;"&gt;&lt;b style="font-weight:bold;"&gt;7. Commitments and contingencies&lt;/b&gt;&lt;/p&gt;&lt;p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"&gt;The Company records a provision for contingent losses when it is both probable that a liability has been incurred and the amount of the loss can be reasonably estimated. As of September&#160;30,&#160;2024, the Company has not recorded a provision for any contingent losses.&lt;/p&gt;</us-gaap:CommitmentsAndContingenciesDisclosureTextBlock>
    <us-gaap:LossContingencyAccrualProvision
      contextRef="Duration_1_1_2024_To_9_30_2024_evSZpCMaEkSRtn4RjrAQdA"
      decimals="0"
      id="Narr_QIzVBwuwjEuF-USauq9oag"
      unitRef="Unit_Standard_USD_kvBPk_S4wkKFTfsbG_xqAw">0</us-gaap:LossContingencyAccrualProvision>
</xbrl>
