<SEC-DOCUMENT>0001104659-26-051739-index.html : 20260429
<SEC-HEADER>0001104659-26-051739.hdr.sgml : 20260429
<ACCEPTANCE-DATETIME>20260429171539
ACCESSION NUMBER:		0001104659-26-051739
CONFORMED SUBMISSION TYPE:	424B3
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20260429
DATE AS OF CHANGE:		20260429

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Aprea Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001781983
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-295247
		FILM NUMBER:		26918036

	BUSINESS ADDRESS:	
		STREET 1:		3805 OLD EASTON ROAD
		CITY:			DOYLESTOWN
		STATE:			PA
		ZIP:			18902
		BUSINESS PHONE:		215-948-4119

	MAIL ADDRESS:	
		STREET 1:		3805 OLD EASTON ROAD
		CITY:			DOYLESTOWN
		STATE:			PA
		ZIP:			18902
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B3
<SEQUENCE>1
<FILENAME>tm2612147-4_424b3.htm
<DESCRIPTION>424B3
<TEXT>
Document 1 - file: tm2612147-4_424b3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>lg_apreatherapeutic-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: lg_apreatherapeutic-4c.jpg

</DOCUMENT>
</SEC-DOCUMENT>