<SEC-DOCUMENT>0001037389-21-000144-index.html : 20210211
<SEC-HEADER>0001037389-21-000144.hdr.sgml : 20210211
<ACCEPTANCE-DATETIME>20210210200705
ACCESSION NUMBER:		0001037389-21-000144
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20210211
DATE AS OF CHANGE:		20210210

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Seneca Biopharma, Inc.
		CENTRAL INDEX KEY:			0001357459
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				522007292
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-86724
		FILM NUMBER:		21615997

	BUSINESS ADDRESS:	
		STREET 1:		20271 GOLDENROD LANE
		STREET 2:		STE 2024
		CITY:			GERMANTOWN
		STATE:			MD
		ZIP:			20876
		BUSINESS PHONE:		301-366-4841

	MAIL ADDRESS:	
		STREET 1:		20271 GOLDENROD LANE
		STREET 2:		STE 2024
		CITY:			GERMANTOWN
		STATE:			MD
		ZIP:			20876

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Neuralstem, Inc.
		DATE OF NAME CHANGE:	20060324

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			RENAISSANCE TECHNOLOGIES LLC
		CENTRAL INDEX KEY:			0001037389
		IRS NUMBER:				260385758
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		800 THIRD AVE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		2124866780

	MAIL ADDRESS:	
		STREET 1:		800 THIRD AVE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	RENAISSANCE TECHNOLOGIES CORP
		DATE OF NAME CHANGE:	19990324
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>snca-13g_20201231.txt
<TEXT>
Document 1 - file: snca-13g_20201231.txt

</DOCUMENT>
</SEC-DOCUMENT>