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Note 6 - Equity Incentive Plans (Details Textual) - USD ($) | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2024 | Jun. 30, 2024 | Sep. 30, 2023 | Sep. 30, 2024 | Sep. 30, 2023
Share-based compensation expense | $ 92,000 |  | $ 192,000 | $ 563,000 | $ 429,000
Unrecognized compensation cost related to outstanding options | 300,000 |  |  | $ 300,000 |
Unrecognized compensation cost weighted-average period of recognition |  |  |  | 1 year 7 months 2 days |
Non-vested, Weighted Average Contractual Life (Years) |  |  |  | 8 months 4 days |
Maximum shares issued under ESPP |  |  |  | $ 11,000 |
General and Administrative Expense [Member] |  |  |  |  |
Share-based compensation expense | 62,000 |  | 122,000 | 324,000 | 243,000
Research and Development Expense [Member] |  |  |  |  |
Share-based compensation expense | 30,000 |  | 70,000 | 239,000 | $ 186,000
Restricted Stock Units [Member] |  |  |  |  |
Unrecognized compensation cost related to outstanding RSUs | 14,000 |  |  | $ 14,000 |
Number of Restricted Stock Units, Granted |  |  |  |  | 20,746
Weighted-average grant date fair value of RSU |  |  |  |  | $ 25.17
Performance Based Stock Units [Member] |  |  |  |  |
Number of Restricted Stock Units, Granted |  |  |  |  | 4,576
Weighted-average grant date fair value of RSU |  |  |  |  | $ 16.9
Stock Option [Member] |  |  |  |  |
Number of Options Granted (in shares) |  |  |  | 12,300 | 33,997
Weighted-average grant date fair value of options |  |  |  |  | $ 13.89
Time-based RSU [Member] | General and Administrative Expense [Member] |  |  |  |  |
Share-based compensation expense |  | $ 129,000 |  |  |
Time-based RSU [Member] | Research and Development Expense [Member] |  |  |  |  |
Share-based compensation expense |  | $ 125,000 |  |  |
The 2021 ESPP [Member] |  |  |  |  |
Percentage of purchase price of common stock |  |  |  | 85.00% |
The 2021 ESPP [Member] | Maximum [Member] |  |  |  |  |
Maximum shares issued under ESPP |  |  |  | $ 25,000,000 |
Shares issued under the ESPP. |  |  |  | 666 |
The ESPP [Member] |  |  |  |  |
Share based compensation expense | $ 3,000 |  | $ 10,000 | $ 12,000 | $ 10,000
Equity Incentive Plan [Member] |  |  |  |  |
Common stock capital shares reserved for future issuance (in shares) | 0 |  |  | 0 |
Equity Incentive Plan [Member] | Stock Option [Member] |  |  |  |  |
Weighted-average grant date fair value of options |  |  |  | $ 3.8 |

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