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Note 6 - Equity Incentive Plans (Details Textual) - USD ($)	3 Months Ended			9 Months Ended
	Sep. 30, 2024	Jun. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Share-based compensation expense	$ 92,000		$ 192,000	$ 563,000	$ 429,000
Unrecognized compensation cost related to outstanding options	300,000			$ 300,000
Unrecognized compensation cost weighted-average period of recognition				1 year 7 months 2 days
Non-vested, Weighted Average Contractual Life (Years)				8 months 4 days
Maximum shares issued under ESPP				$ 11,000
General and Administrative Expense [Member]
Share-based compensation expense	62,000		122,000	324,000	243,000
Research and Development Expense [Member]
Share-based compensation expense	30,000		70,000	239,000	$ 186,000
Restricted Stock Units [Member]
Unrecognized compensation cost related to outstanding RSUs	14,000			$ 14,000
Number of Restricted Stock Units, Granted					20,746
Weighted-average grant date fair value of RSU					$ 25.17
Performance Based Stock Units [Member]
Number of Restricted Stock Units, Granted					4,576
Weighted-average grant date fair value of RSU					$ 16.9
Stock Option [Member]
Number of Options Granted (in shares)				12,300	33,997
Weighted-average grant date fair value of options					$ 13.89
Time-based RSU [Member] | General and Administrative Expense [Member]
Share-based compensation expense		$ 129,000
Time-based RSU [Member] | Research and Development Expense [Member]
Share-based compensation expense		$ 125,000
The 2021 ESPP [Member]
Percentage of purchase price of common stock				85.00%
The 2021 ESPP [Member] | Maximum [Member]
Maximum shares issued under ESPP				$ 25,000,000
Shares issued under the ESPP.				666
The ESPP [Member]
Share based compensation expense	$ 3,000		$ 10,000	$ 12,000	$ 10,000
Equity Incentive Plan [Member]
Common stock capital shares reserved for future issuance (in shares)	0			0
Equity Incentive Plan [Member] | Stock Option [Member]
Weighted-average grant date fair value of options				$ 3.8

X

- Definition

Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

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Amount of expense recognized from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments), awarded to key employees or individuals. Excludes amount related to plans that cover generally all employees (for example, but not limited to, qualified pension plans).

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Amount of cost to be recognized for nonvested award under share-based payment arrangement. Excludes share and unit options.

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The number of grants made during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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Weighted average remaining contractual term for equity-based awards excluding options, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Gross number of share options (or share units) granted during the period.

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