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Note 7 - Collaborations and License Agreements (Details Textual))
3 Months Ended 9 Months Ended 36 Months Ended
Oct. 27, 2022
USD ($)
Sep. 30, 2024
USD ($)
Agreement
shares
Dec. 31, 2023
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2024
USD ($)
Agreement
shares
Sep. 30, 2023
USD ($)
Dec. 16, 2023
USD ($)
Oct. 20, 2023
Agreement
Collaborations and License Agreements Upfront Fee $ 0       $ 1,000,000      
Royalty Expense         6,750,000   $ 4,500,000  
Maximum Aggregate Consideration             5,000,000  
License revenue         300,000      
Accrued joint development expenses   $ 669,000 $ 98,000   669,000      
Milestone Payments             $ 1,500,000  
Closing period of merger agreement             48 months  
Proceeds Deposited into the CVR Escrow             20.00%  
Research and development expense   $ 16,000,000 $ 362,000   $ 16,000,000      
Contingent value right issued | shares   1     1      
Contingent value right, pro rata, net proceeds from sale or licensing         80.00%      
Research and Development Expense [Member]                
Joint development expenses   $ 900,000     $ 4,300,000      
Minimum [Member]                
CVR Agreement, distribution minimum amount         $ 300,000   $ 300,000  
License Agreements with the Regents of the University of California [Member]                
Number of License Agreements | Agreement   3     3      
Number of terminated license agreements | Agreement               2
Sublicense Fees       $ 0   $ 25,000,000    
Period of Expiration of License Agreement Description         The 2015 UC License will expire upon the expiration date of the longest-lived patent right licensed under the 2015 UC License. The Regents may terminate the 2015 UC License if: (i) a material breach by us is not cured within 60 days, (ii) the Company files a claim asserting the Regents licensed patent rights are invalid or unenforceable, or (iii) the Company files for bankruptcy. The Company also has the right to terminate the 2015 UC License at any time upon at least 90 days’ written notice.      
License Agreements with the Regents of the University of California [Member] | Research and Development Expense [Member]                
Accrued Royalties, Current   $ 0   $ 21,000,000 $ 0 $ 21,000,000    
License Agreements with the Regents of the University of California [Member] | Maximum [Member]                
Royalty Rate, Portion of Sublicense Income to Be Paid, Percentage of One-third of Upfront Payment and Milestone Payment Received   35.00%     35.00%      
License Agreements with the Regents of the University of California [Member] | Minimum [Member]                
Royalty Rate, Portion of Sublicense Income to Be Paid, Percentage of One-third of Upfront Payment and Milestone Payment Received   30.00%     30.00%      
NSI-532.IGF-1 [Member]                
Percentage Cost in Patent Right 100.00%              
Percentage of net revenue 50.00%