<SEC-DOCUMENT>0001493152-24-006047.txt : 20240213
<SEC-HEADER>0001493152-24-006047.hdr.sgml : 20240213
<ACCEPTANCE-DATETIME>20240213150845
ACCESSION NUMBER:		0001493152-24-006047
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20240208
FILED AS OF DATE:		20240213
DATE AS OF CHANGE:		20240213

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Csimma Cristina
		CENTRAL INDEX KEY:			0001501623
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33672
		FILM NUMBER:		24625064

	MAIL ADDRESS:	
		STREET 1:		14 CAMBRIDGE CENTER, BLDG 1
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PALISADE BIO, INC.
		CENTRAL INDEX KEY:			0001357459
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				522007292
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		7750 EL CAMINO REAL, SUITE 5200
		CITY:			CARLSBAD
		STATE:			CA
		ZIP:			92009
		BUSINESS PHONE:		(858) 704-4900

	MAIL ADDRESS:	
		STREET 1:		7750 EL CAMINO REAL, SUITE 5200
		CITY:			CARLSBAD
		STATE:			CA
		ZIP:			92009

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Seneca Biopharma, Inc.
		DATE OF NAME CHANGE:	20200127

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Neuralstem, Inc.
		DATE OF NAME CHANGE:	20060324
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
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        <issuerName>PALISADE BIO, INC.</issuerName>
        <issuerTradingSymbol>PALI</issuerTradingSymbol>
    </issuer>

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            <rptOwnerName>Csimma Cristina</rptOwnerName>
        </reportingOwnerId>
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            <rptOwnerStreet2></rptOwnerStreet2>
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            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92009</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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            <isDirector>1</isDirector>
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            <expirationDate>
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    <footnotes>
        <footnote id="F1">Represents the issuance of common stock upon the vesting and settlement of outstanding restricted stock units granted on June 11, 2023, resulting from the full accelerated vesting in connection with Reporting Person's resignation from the Issuer's Board of Directors.</footnote>
        <footnote id="F2">Represents the issuance of common stock upon the vesting and settlement of outstanding restricted stock units granted on November 21, 2023, resulting from the full accelerated vesting in connection with Reporting Person's resignation from the Issuer's Board of Directors.</footnote>
        <footnote id="F3">This restricted stock unit was granted on June 11, 2023 and pursuant to the issuance upon full vesting as described in Footnote 1, is no longer outstanding.</footnote>
        <footnote id="F4">This restricted stock unit was granted on November 21, 2023 and pursuant to the issuance upon full vesting described in Footnote 2, is no longer outstanding.</footnote>
        <footnote id="F5">Each restricted stock unit represents the right to receive one share of common stock.</footnote>
        <footnote id="F6">Each option represents the right to purchase one share of common stock at the exercise price.</footnote>
        <footnote id="F7">Represents the modification of the option granted on June 11, 2023, resulting in (i) immediate vesting in full of the outstanding grant and (ii) extension of the exercise period until the expiration date in connection with Reporting Person's resignation from the Issuer's Board of Directors.</footnote>
        <footnote id="F8">Represents the modification of the option granted on November 21, 2023, resulting in (i) immediate vesting in full of the outstanding grant and (ii) extension of the exercise period until the expiration date in connection with Reporting Person's resignation from the Issuer's Board of Directors.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Cristina Csimma</signatureName>
        <signatureDate>2024-02-13</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</TEXT>
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</SEC-DOCUMENT>
