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    PUBLIC DOCUMENT COUNT:		32
    FILED AS OF DATE:		20241122
    DATE AS OF CHANGE:		20241122

    SUBJECT COMPANY:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			PALISADE BIO, INC.
    		CENTRAL INDEX KEY:			0001357459
    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
    		ORGANIZATION NAME:           	03 Life Sciences
    		IRS NUMBER:				522007292
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		FWP
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	333-282883
    		FILM NUMBER:		241490851

    	BUSINESS ADDRESS:
    		STREET 1:		7750 EL CAMINO REAL, SUITE 5200
    		CITY:			CARLSBAD
    		STATE:			CA
    		ZIP:			92009
    		BUSINESS PHONE:		(858) 704-4900

    	MAIL ADDRESS:
    		STREET 1:		7750 EL CAMINO REAL, SUITE 5200
    		CITY:			CARLSBAD
    		STATE:			CA
    		ZIP:			92009

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Seneca Biopharma, Inc.
    		DATE OF NAME CHANGE:	20200127

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Neuralstem, Inc.
    		DATE OF NAME CHANGE:	20060324

    FILED BY:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			PALISADE BIO, INC.
    		CENTRAL INDEX KEY:			0001357459
    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
    		ORGANIZATION NAME:           	03 Life Sciences
    		IRS NUMBER:				522007292
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		FWP

    	BUSINESS ADDRESS:
    		STREET 1:		7750 EL CAMINO REAL, SUITE 5200
    		CITY:			CARLSBAD
    		STATE:			CA
    		ZIP:			92009
    		BUSINESS PHONE:		(858) 704-4900

    	MAIL ADDRESS:
    		STREET 1:		7750 EL CAMINO REAL, SUITE 5200
    		CITY:			CARLSBAD
    		STATE:			CA
    		ZIP:			92009

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Seneca Biopharma, Inc.
    		DATE OF NAME CHANGE:	20200127

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Neuralstem, Inc.
    		DATE OF NAME CHANGE:	20060324
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