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Note 5 - Stockholders' Equity (Tables) | 12 Months Ended
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Dec. 31, 2024
Table Text Block [Abstract] |
Schedule of Stockholders' Equity warrant outstanding and exercisable. | The following table summarizes the Company's outstanding and exercisable common stock warrants as of December 31, 2024:
Common Stock Warrants |  | Classification |  | Number of Warrants Outstanding |  |  | Weighted Average Exercise Price |  |  | Weighted Average Remaining Contractual Life (Years) |  |
December 2024 Offering Pre-Funded Common Stock Warrants |  | Equity-classified |  |  | 2,027,000 |  |  | $ | 0.0001 |  |  | Perpetual |  |
December 2024 Offering Common Stock Warrants |  | Equity-classified |  |  | 3,278,688 |  |  |  | 1.40 |  |  |  | 4.95 |  |
May 2024 Offering Common Stock Warrants |  | Equity-classified |  |  | 922,863 |  |  |  | 1.40 |  |  |  | 6.34 |  |
February 2024 Warrant Inducement Replacement Common Stock Warrants |  | Equity-classified |  |  | 228,158 |  |  |  | 6.17 |  |  |  | 4.09 |  |
August 2024 Offering Series 2 Common Stock Warrants |  | Equity-classified |  |  | 6,748 |  |  |  | 1.40 |  |  |  | 2.61 |  |
Bridge, January 2021, and July 2021 Common Stock Warrants |  | Liability-Classified |  |  | 1,144 |  |  |  | 58.20 |  |  |  | 1.75 |  |
Placement Agent, Solicitor and Representative Common Stock Warrants |  | Equity-classified |  |  | 274,693 |  |  |  | 10.98 |  |  |  | 4.66 |  |
All Other Common Stock Warrants |  | Equity-classified |  |  | 5,919 |  |  |  | 3,418.56 |  |  |  | 1.50 |  |
Total Warrants Outstanding, December 31, 2024 |  |  |  |  | 6,745,213 |  |  |  | 4.53 |  |  |  | 5.16 |  | (1)
(1) The pre-funded common stock warrants granted and outstanding during the year ended December 31, 2024 have a perpetual
Schedule of Stockholders' Equity Note, Warrants or Rights | The following table summarizes all common stock warrant activity for the year ended December 31, 2024:
|  | Number of Warrants |  |  | Weighted Average Exercise Price |  |  | Weighted Average Remaining Contractual Life (Years) |  |
Warrants outstanding, December 31, 2023 |  |  | 272,211 |  |  | $ | 144.78 |  |  |  | 4.12 |  |
Granted |  |  | 8,327,864 |  |  |  | 1.68 |  |  |  | 5.27 |  | (1)
Exercised |  |  | (1,854,658 | ) |  |  | 1.35 |  |  |  | — |  |
Forfeited, expired or cancelled |  |  | (204 | ) |  |  | 17,438.12 |  |  |  | — |  |
Warrants outstanding, December 31, 2024 |  |  | 6,745,213 |  |  |  | 4.53 |  |  |  | 5.16 |  | (1)
(1) The pre-funded common stock warrants granted and outstanding during the year ended December 31, 2024 have a perpetual term and are therefore excluded from the calculation of the weighted average remaining contractual life.

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- Definition Tabular disclosure of warrants outstanding and exercisable. + References No definition available. + Details
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- Definition Tabular disclosure of warrants or rights issued. Warrants and rights outstanding are derivative securities that give the holder the right to purchase securities (usually equity) from the issuer at a specific price within a certain time frame. Warrants are often included in a new debt issue to entice investors by a higher return potential. The main difference between warrants and call options is that warrants are issued and guaranteed by the company, whereas options are exchange instruments and are not issued by the company. Also, the lifetime of a warrant is often measured in years, while the lifetime of a typical option is measured in months. Disclose the title of issue of securities called for by warrants and rights outstanding, the aggregate amount of securities called for by warrants and rights outstanding, the date from which the warrants or rights are exercisable, and the price at which the warrant or right is exercisable. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-1 + Details
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