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Note 12 - Segment Information - Schedule of Reconciliation of Loss from Operations Disclosure Disclosure (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023
Segment Reporting Information [Line Items] |  |
Restructuring costs | $ 0 | $ 225
Total operating expenses | 14,859 | 13,320
Operating Segments [Member] |  |
Segment Reporting Information [Line Items] |  |
Other research and development expenses | 2,156 | 2,987
Other general and administrative expenses | 5,478 | 6,069
Restructuring costs | 0 | 225
Total operating expenses | 14,859 | 13,320
Operating Segments [Member] | PALI-2108 [Member] |  |
Segment Reporting Information [Line Items] |  |
Program expenses | 7,070 | 736
Operating Segments [Member] | Legacy [Member] |  |
Segment Reporting Information [Line Items] |  |
Program expenses | $ 155 | $ 3,303

X
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X
- Definition Amount of general and administrative expense classified as other. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 220 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03(4)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147483621/220-10-S99-2 Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 946 -SubTopic 220 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.6-07(2)(b)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479134/946-220-S99-1 + Details
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- Definition Amount, after cash payment, of expenses associated with exit or disposal activities pursuant to an authorized plan. Excludes expenses related to a discontinued operation or an asset retirement obligation. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 45 -Paragraph 28 -Subparagraph (b) -SubTopic 10 -Topic 230 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482740/230-10-45-28 + Details
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- Details
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