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Note 5 - Stockholders' Equity (Details Textual) - USD ($)
12 Months Ended
Dec. 12, 2024
May 06, 2024
May 01, 2024
Apr. 05, 2024
Feb. 01, 2024
Jan. 30, 2024
Sep. 11, 2023
Apr. 03, 2023
Jan. 04, 2023
Dec. 31, 2024
Dec. 31, 2023
Dec. 13, 2024
Common Stock, Shares Authorized (in shares)                   280,000,000 280,000,000  
Common Stock, Par or Stated Value Per Share (in dollars per share)                   $ 0.01 $ 0.01  
Reverse stock split fractional share settlement       15                
Common stock warrants [1]                   6,745,213    
Warrants exercise price of common stock warrants [1]                   $ 4.53    
Common stock, shares issued (in shares)                   2,768,646 618,056  
Common stock, shares outstanding (in shares)                   2,768,646 618,056  
Proceeds from issuance of common stock and warrants                   $ 8,435,000 $ 9,419,000  
Payment of equity issuance costs                   576,000 617,000  
Warrants and Rights Outstanding                   $ 6,745,213 272,211  
Pre Funded Warrants [Member]                        
Warrants to purchase shares of common stock                   2,027,000   3,120,688
Warrants exercise price of common stock warrants                       $ 0.0001
Replacement Warrants [Member]                        
Warrants exercise price of common stock warrants         $ 10.97              
Date of issuance of warrant         5 years              
Common Stock [Member]                        
Offering shares (Per share)       15                
Reverse stock split fractional share settlement [2]                   (102)    
Common Stock [Member] | Maximum [Member]                        
Reverse stock split fractional share settlement       12,771,015                
Common Stock [Member] | Minimum [Member]                        
Reverse stock split fractional share settlement       851,302                
Private Placement [Member]                        
Warrants to purchase shares of common stock     922,863                  
Warrants exercise price of common stock warrants     $ 6.314                  
Date of issuance of warrant     7 years                  
Private Placement [Member] | Pre Funded Warrants [Member]                        
Warrants to purchase shares of common stock     530,142                  
Common stock warrants     6.5014                  
Warrants exercise price of common stock warrants     $ 0.0001                  
December 2024 Offering Common Stock Warrants [Member]                        
Common stock warrants                   3,278,688    
Warrants exercise price of common stock warrants                   $ 1.4    
May Two Thousand Twenty Four Offering [Member]                        
Common stock warrants                   922,863    
Warrants exercise price of common stock warrants                   $ 1.4    
Proceeds from issuance of common stock and warrants   $ 4,000,000                    
Payment of equity issuance costs   500,000                    
Net Proceeds   3,500,000                    
Grant date fair value   $ 200,000                    
Sale of stock during period     85,100                  
May Two Thousand Twenty Four Offering [Member] | Unregistered Shares [Member]                        
Shares Sold, Price Per Share     $ 6.5015                  
May 2024 Placement Agent Warrants [Member]                        
Warrants to purchase shares of common stock     36,914                  
Warrants exercise price of common stock warrants     $ 10.727                  
Date of issuance of warrant     5 years                  
February 2024 Warrant Inducement [Member]                        
Warrants to purchase shares of common stock           228,162            
Net proceeds from exercise of warrants         $ 2,200,000              
Gross proceeds from the exercise of warrants         2,500,000              
Cash transaction-related expenses And placement agent fees         300,000              
Common stock warrants           228,162            
Warrants exercise price of common stock warrants           $ 10.97            
Total equity issuance costs           $ 2,400,000            
Payment of equity issuance costs         $ 2,000,000 300,000            
Non-cash warrant modification costs           $ 2,000,000            
February 2024 Warrant Inducement [Member] | Replacement Warrants [Member]                        
Warrants to purchase shares of common stock           228,162            
February 2024 Warrant Inducement [Member] | May 2022 Warrants [Member]                        
Common stock warrants           4,865            
February 2024 Warrant Inducement [Member] | Series 2 Warrants [Member]                        
Common stock warrants           4,267            
February 2024 Warrant Inducement [Member] | January 2023 Warrants [Member]                        
Common stock warrants           67,511            
February 2024 Warrant Inducement [Member] | April 2023 Warrants [Member]                        
Common stock warrants           151,519            
Placement Agent Warrants [Member]                        
Warrants exercise price of common stock warrants           $ 10.97            
Date of issuance of warrant           5 years            
Out-of-pocket expenses           $ 35,000            
Non-cash warrant issuance costs           $ 100,000            
Percentage of gross proceeds           7.75%            
Percentage of share issued           6.00%            
December 2022 Warrants [Member]                        
Proceeds from issuance of common stock and warrants                   $ 2,500,000 2,800,000  
Net Proceeds                     $ 1,400,000  
Series A 4.5% Convertible Preferred Stock [Member]                        
Preferred stock, shares authorized (in shares)                   1,000,000    
Preferred Stock, Par or Stated Value Per Share (in dollars per share)                   $ 0.01    
Convertible Preferred Stock, Issuable Upon Conversion of All Shares (in shares)                   8    
Series A Preferred Stock [Member]                        
Preferred stock, shares authorized (in shares)                   7,000,000 7,000,000  
Preferred Stock, Par or Stated Value Per Share (in dollars per share)                   $ 0.01 $ 0.01  
Common stock, shares issued (in shares)                   200,000    
Common stock, shares outstanding (in shares)                   200,000    
Convertible Preferred Stock issued and outstanding                   200,000    
December 2024 Offering [Member]                        
Warrants to purchase shares of common stock                   196,721    
Option to purchase shares of Company's common stock                   491,803    
Warrants exercise price of common stock warrants                   $ 1.4    
Date of issuance of warrant                   5 years    
Proceeds from issuance of common stock and warrants                   $ 5,000,000    
Payment of equity issuance costs                   900,000    
Net Proceeds                   4,100,000    
Grant date fair value                   $ 300,000    
December 2024 Offering [Member] | Pre Funded Warrants [Member]                        
Warrants exercise price of common stock warrants                   $ 0.0001    
December 2024 Offering [Member] | Class A Units [Member]                        
Common Stock, Par or Stated Value Per Share (in dollars per share)                   $ 0.01    
Offering shares (Per share)                   158,000    
Underwriting agreement, per share                   $ 1.525    
December 2024 Offering [Member] | Class B Units [Member]                        
Offering shares (Per share)                   3,120,688    
Underwriting agreement, per share                   $ 1.5249    
December 2024 Offering [Member] | December 2024 Representative Warrants [Member]                        
Warrants exercise price of common stock warrants                   $ 2.51625    
December 2024 Offering [Member] | Repriced Warrants [Member]                        
Common stock warrants 1,040,217                      
Warrants exercise price of common stock warrants $ 1.4                      
Proceeds from issuance of common stock and warrants $ 5,000,000                      
Payment of equity issuance costs $ 300,000                      
Incremental fair value of Warrants                   $ 300,000    
September 2023 Offering [Member]                        
Proceeds from issuance of common stock and warrants             $ 2,000,000          
Payment of equity issuance costs             300,000          
Net Proceeds             $ 1,700,000          
April 2023 Offering [Member]                        
Proceeds from issuance of common stock and warrants               $ 6,000,000        
Payment of equity issuance costs               700,000        
Net Proceeds               $ 5,300,000        
January 2023 Offering [Member]                        
Proceeds from issuance of common stock and warrants                 $ 2,500,000      
Payment of equity issuance costs                 300,000      
Net Proceeds                 $ 2,200,000      
[1]

(1) The pre-funded common stock warrants granted and outstanding during the year ended December 31, 2024 have a perpetual term and are therefore excluded from the calculation of the weighted average remaining contractual life.

[2]

(*) Adjusted to reflect the 1-for-15 reverse stock split effected on April 5, 2024.