Number Of Trading Days

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- Definition

Share based compensation arrangement by share based payment award fair value assumptions Cost of equity.

+ References

No definition available.

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Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

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- Definition

Aggregate number of common shares reserved for future issuance.

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- Definition

Amount of expense recognized from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments), awarded to key employees or individuals. Excludes amount related to plans that cover generally all employees (for example, but not limited to, qualified pension plans).

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No definition available.

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- Definition

Weighted-average period over which cost not yet recognized is expected to be recognized for award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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- Definition

Amount of cost to be recognized for nonvested award under share-based payment arrangement. Excludes share and unit options.

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- Definition

Amount of cost to be recognized for option under share-based payment arrangement.

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- Definition

Estimated period over which an employee is required to provide service in exchange for the equity-based payment award, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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-Paragraph 2
-Subparagraph (a)(1)
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- Definition

The number of equity-based payment instruments, excluding stock (or unit) options, that were forfeited during the reporting period.

+ References

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- Definition

The number of grants made during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

+ References

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- Definition

The weighted average fair value at grant date for nonvested equity-based awards issued during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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- Definition

Per share or unit weighted-average fair value of nonvested award under share-based payment arrangement. Excludes share and unit options.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 718
-SubTopic 10
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- Definition

The number of equity-based payment instruments, excluding stock (or unit) options, that vested during the reporting period.

+ References

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- Definition

The estimated measure of the percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period.

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- Definition

The risk-free interest rate assumption that is used in valuing an option on its own shares.

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- Definition

The highest quantity of shares an employee can purchase under the plan per period.

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- Definition

Gross number of share options (or share units) granted during the period.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition

The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology.

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- Definition

Percentage of vesting of award under share-based payment arrangement.

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- Definition

Intrinsic value of vested award under share-based payment arrangement. Excludes share and unit options.

+ References

No definition available.

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- Definition

Expected term of award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition

Number of non-vested options outstanding.

+ References

No definition available.

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- Definition

Purchase price of common stock expressed as a percentage of its fair value.

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No definition available.

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- Definition

Number of shares issued during the period as a result of an employee stock purchase plan.

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- Definition

Aggregate change in value for stock issued during the period as a result of employee stock purchase plan.

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Note 6 - Equity Incentive Plans (Details Textual)			1 Months Ended	3 Months Ended	12 Months Ended
Note 6 - Equity Incentive Plans (Details Textual)	Aug. 07, 2023 shares	Feb. 06, 2023 Days $ / shares shares	Apr. 30, 2021 USD ($) shares	Jun. 30, 2024 USD ($)	Dec. 31, 2024 USD ($) $ / shares shares	Dec. 31, 2023 USD ($) $ / shares shares
Number of options, Granted (in shares)					12,300
Maximum shares issued under ESPP \| $					$ 11,000	$ 17,000
Weighted-average grant date fair value of options granted \| $ / shares					$ 3.8	$ 12.33
Unrecognized compensation cost weighted-average period of recognition					1 year 5 months 26 days
Unrecognized compensation cost related to outstanding options \| $					$ 200,000
Grant date fair value of the options vested \| $					400,000	$ 300,000
Share-Based Payment Arrangement, Expense \| $					633,000	606,000
Research and Development Expense [Member]
Share-Based Payment Arrangement, Expense \| $					263,000	240,000
General and Administrative Expense [Member]
Share-Based Payment Arrangement, Expense \| $					370,000	366,000
Restricted Stock Units [Member]
Grant date fair value of the options vested \| $					100,000	$ 100,000
Unrecognized compensation cost related to outstanding RSUs \| $					$ 0
Performance Based Stock Units [Member]
Number of Restricted Stock Units, Granted		4,580
Number of Stock Units, Vested					0
Risk free interest rate					3.74%
Expected stock price volatility					76.60%
Cost of equity					27.99%
Expected contractual life					9 years 7 months 28 days
Number of shares forfeited					1,192
Number of shares unvested and outstanding					2,952	4,144
Performance Based Stock Units [Member] \| Tranche One [Member]
Exercise price \| $ / shares		$ 48
Award Vesting Rights Percentage		50.00%
Consecutive trading day period \| Days		20
Granted, Weighted Average Grant Date Fair Value \| $ / shares					$ 22.5
Service period					1 year 9 months
Performance Based Stock Units [Member] \| Tranche Two [Member]
Exercise price \| $ / shares		$ 63.75
Award Vesting Rights Percentage		50.00%
Consecutive trading day period \| Days		20
Granted, Weighted Average Grant Date Fair Value \| $ / shares					$ 22.05
Service period					2 years 5 months 23 days
Time-based RSU [Member] \| Research and Development Expense [Member]
Share-Based Payment Arrangement, Expense \| $				$ 125,000
Time-based RSU [Member] \| General and Administrative Expense [Member]
Share-Based Payment Arrangement, Expense \| $				$ 129,000
The 2021 EIP and Inducement Plan [Member]
Common Stock capital shares reserved for future issuance (in shares)					37,586
The 2021 EIP and Inducement Plan [Member] \| Restricted Stock Units [Member]
Number of Restricted Stock Units, Granted					0
Number of Stock Units, Vested					23,067
Exercise price \| $ / shares					$ 0	$ 17.3
Granted, Weighted Average Grant Date Fair Value \| $ / shares					$ 0
Number of shares forfeited					1,128
2013 Plan [Member]
Common Stock capital shares reserved for future issuance (in shares)					0
The 2021 ESPP [Member]
Common Stock capital shares reserved for future issuance (in shares)					19,086
Percentage of purchase price of common stock			85.00%
Maximum number of shares per employee (in shares)			5,000
Maximum shares issued under ESPP \| $			$ 25,000,000
Shares issued under the ESPP					4,501
Share based compensation expense \| $					$ 19,000,000	$ 18,000,000
2021 Inducement Plan [Member]
Common Stock capital shares reserved for future issuance (in shares)					52,941
Number of options, Granted (in shares)	66,666