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Stockholders' Equity (Deficit) (Tables) | 9 Months Ended
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Sep. 30, 2018
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] |
Schedule of Share-based Compensation, Allocation of Recognized Period Costs | Total stock-based compensation expense for employees and non-employees recognized in the statements of operations was as follows (in thousands):
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2018 |  |  | 2017 |  |  | 2018 |  |  | 2017 |
|  | (unaudited) |  |  | (unaudited) |
Research and development |  | $ | 475 |  |  | $ | 322 |  |  | $ | 1,217 |  |  | $ | 676 |
General and administrative |  |  | 519 |  |  |  | 267 |  |  |  | 1,347 |  |  |  | 541 |
Total stock-based compensation expense |  | $ | 994 |  |  | $ | 589 |  |  | $ | 2,564 |  |  | $ | 1,217 |
Schedule of Stock Option and Restricted Stock Activity | The table below summarizes stock option and restricted award activity under the 2011 and 2018 Plan:
|  | Number of Shares Outstanding |  |  | Weighted- Average Exercise Price |  |  | Weighted- Average Remaining Contractual Term (Years) |  |  | Aggregate Intrinsic Value (in thousands) |
Balances at December 31, 2017 |  |  | 2,506,926 |  |  | $ | 3.50 |  |  |  | 8.79 |  |  | $ | 24,033 |
Forfeited |  |  | (6,772 | ) |  | $ | 7.01 |  |  |  |  |  |  |  |  |
Exercised |  |  | (254,186 | ) |  | $ | 1.94 |  |  |  |  |  |  |  | 1,786 |
Granted |  |  | 804,099 |  |  | $ | 9.87 |  |  |  |  |  |  |  |  |
Balances at September 30, 2018 |  |  | 3,050,067 |  |  | $ | 5.31 |  |  |  | 8.53 |  |  | $ | 14,880 |

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- Definition Tabular disclosure of the amount of total share-based compensation cost, including the amounts attributable to each share-based compensation plan and any related tax benefits. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure for share-based compensation plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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