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Stockholders' Equity (Deficit) (Tables)
9 Months Ended
Sep. 30, 2018
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]  
Schedule of Share-based Compensation, Allocation of Recognized Period Costs

Total stock-based compensation expense for employees and non-employees recognized in the statements of operations was as follows (in thousands):

 

 

 

Three Months Ended September 30,

 

 

Nine Months Ended September 30,

 

 

 

2018

 

 

2017

 

 

2018

 

 

2017

 

 

 

(unaudited)

 

 

(unaudited)

 

Research and development

 

$

475

 

 

$

322

 

 

$

1,217

 

 

$

676

 

General and administrative

 

 

519

 

 

 

267

 

 

 

1,347

 

 

 

541

 

Total stock-based compensation expense

 

$

994

 

 

$

589

 

 

$

2,564

 

 

$

1,217

 

 

Schedule of Stock Option and Restricted Stock Activity

The table below summarizes stock option and restricted award activity under the 2011 and 2018 Plan:

 

 

 

Number of

Shares

Outstanding

 

 

Weighted-

Average

Exercise

Price

 

 

Weighted-

Average

Remaining

Contractual

Term (Years)

 

 

Aggregate

Intrinsic

Value

(in thousands)

 

Balances at December 31, 2017

 

 

2,506,926

 

 

$

3.50

 

 

 

8.79

 

 

$

24,033

 

Forfeited

 

 

(6,772

)

 

$

7.01

 

 

 

 

 

 

 

 

 

Exercised

 

 

(254,186

)

 

$

1.94

 

 

 

 

 

 

 

1,786

 

Granted

 

 

804,099

 

 

$

9.87

 

 

 

 

 

 

 

 

 

Balances at September 30, 2018

 

 

3,050,067

 

 

$

5.31

 

 

 

8.53

 

 

$

14,880