<SEC-DOCUMENT>0001209191-20-023804.txt : 20200407
<SEC-HEADER>0001209191-20-023804.hdr.sgml : 20200407
<ACCEPTANCE-DATETIME>20200407172156
ACCESSION NUMBER:		0001209191-20-023804
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20200403
FILED AS OF DATE:		20200407
DATE AS OF CHANGE:		20200407

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Domzalski David
		CENTRAL INDEX KEY:			0001727794

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38356
		FILM NUMBER:		20780473

	MAIL ADDRESS:	
		STREET 1:		C/O FOAMIX PHARMACEUTICALS LTD.
		STREET 2:		2 HOLZMAN STREET, WEIZMANN SCIENCE PARK
		CITY:			REHOVOT
		STATE:			L3
		ZIP:			76704

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Menlo Therapeutics Inc.
		CENTRAL INDEX KEY:			0001566044
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				453757789
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		520 U.S. HIGHWAY 22, SUITE 204
		CITY:			BRIDGEWATER
		STATE:			NJ
		ZIP:			08807
		BUSINESS PHONE:		800-775-7936

	MAIL ADDRESS:	
		STREET 1:		520 U.S. HIGHWAY 22, SUITE 204
		CITY:			BRIDGEWATER
		STATE:			NJ
		ZIP:			08807

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Menlo Therapeutics, Inc.
		DATE OF NAME CHANGE:	20170728

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Tigercat Pharma, Inc.
		DATE OF NAME CHANGE:	20130104
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
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    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2020-04-03</periodOfReport>

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    <issuer>
        <issuerCik>0001566044</issuerCik>
        <issuerName>Menlo Therapeutics Inc.</issuerName>
        <issuerTradingSymbol>MNLO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001727794</rptOwnerCik>
            <rptOwnerName>Domzalski David</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>520 U.S. HIGHWAY 22, SUITE 204</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>BRIDGEWATER</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>08807</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President and CEO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
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            <securityTitle>
                <value>Common Stock</value>
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            <transactionDate>
                <value>2020-04-03</value>
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            <transactionTimeliness>
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            <transactionAmounts>
                <transactionShares>
                    <value>141901</value>
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                <sharesOwnedFollowingTransaction>
                    <value>329397</value>
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                <sharesOwnedFollowingTransaction>
                    <value>578985</value>
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        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2020-04-06</value>
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            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>F</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
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            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>11772</value>
                    <footnoteId id="F4"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.40</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>567213</value>
                </sharesOwnedFollowingTransaction>
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            <ownershipNature>
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    <footnotes>
        <footnote id="F1">As disclosed by the Issuer in its Current Report on Form 8-K filed with the Securities and Exchange Commission on April 6, 2020, following the receipt of certain clinical trial results, Menlo Therapeutics Inc. (&quot;Menlo&quot;) issued additional shares of its common stock pursuant to certain contingent stock rights (&quot;CSRs&quot;) issued in connection with the March 9, 2020 merger (the &quot;Merger&quot;) of Menlo and Foamix Pharmaceuticals Ltd. (&quot;Foamix&quot;), including pursuant to CSRs held by the Reporting Person. The issuance of shares pursuant to the CSRs resulted in an adjustment to the effective exchange ratio applicable to the Merger, from 0.5924 to 1.8006 (the &quot;Final Exchange Ratio&quot;). Menlo derivative securities issued in exchange for Foamix derivative securities in connection with the Merger were also adjusted pursuant to their terms to give effect to the Final Exchange Ratio. The transactions reported in these line items reflect the additional shares and restricted stock unit (continued in footnote 2)</footnote>
        <footnote id="F2">(continued from footnote 1) awards that were received by the reporting person as a result of the foregoing.</footnote>
        <footnote id="F3">Represents restricted stock unit awards, each of which by its terms represents a contingent right to receive one share of common stock of Menlo.</footnote>
        <footnote id="F4">Represents shares that have been withheld by the Issuer to satisfy tax withholding requirements in connection with the vesting of restricted stock units.</footnote>
    </footnotes>

    <remarks>In connection with the events described in footnote 1, each option to purchase shares of Menlo common stock that was acquired by the Reporting Person in connection with the Merger (as reported on the Form 4 filed by the Reporting Person on March 11, 2020) has been adjusted pursuant to its terms.</remarks>

    <ownerSignature>
        <signatureName>/s/ Mutya Harsch, attorney-in-fact for David Domzalski</signatureName>
        <signatureDate>2020-04-07</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
