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CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($) $ in Thousands | Total | At-the-market Offering | Public Offering | Common stock | Common stock At-the-market Offering | Common stock Public Offering | Additional paid-in capital | Additional paid-in capital At-the-market Offering | Additional paid-in capital Public Offering | Accumulated deficit | Accumulated other comprehensive income (loss)
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2019 | $ 17,575 |  |  | $ 1 |  |  | $ 328,156 |  |  | $ (310,587) | $ 5
Balance (shares) at Dec. 31, 2019 |  |  |  | 9,120,078 |  |  |  |  |  |  |
CHANGES DURING THE PERIOD: |  |  |  |  |  |  |  |  |  |  |
Comprehensive (loss) income | (207,678) |  |  |  |  |  |  |  |  | (207,673) | (5)
Exercise of options, vesting of restricted stock units and shares issued under employee stock purchase plan | 260 |  |  |  |  |  | 260 |  |  |  |
Exercise of options, vesting of restricted stock units and shares issued under employee stock purchase plan (in shares) |  |  |  | 258,000 |  |  |  |  |  |  |
Stock-based compensation | 12,527 |  |  |  |  |  | 12,527 |  |  |  |
Deemed dividend to warrants holders due to warrant modifications | 0 |  |  |  |  |  | 41 |  |  | (41) |
Classification of stock awards to derivative liability | (975) |  |  |  |  |  | (975) |  |  |  |
Issuance of common stock, net of issuance costs |  |  | $ 53,649 | $ 1 |  |  |  |  | $ 53,648 |  |
Issuance of common stock, net of issuance costs (in shares) |  |  |  |  |  | 7,776,875 |  |  |  |  |
Issuance of stock related to merger | 196,170 |  |  | $ 2 |  |  | 196,168 |  |  |  |
Issuance of stock related to merger (in shares) |  |  |  | 24,765,999 |  |  |  |  |  |  |
Balance at Jun. 30, 2020 | 71,528 |  |  | $ 4 |  |  | 589,825 |  |  | (518,301) | 0
Balance (shares) at Jun. 30, 2020 |  |  |  | 41,920,952 |  |  |  |  |  |  |
Balance at Mar. 31, 2020 | 69,535 |  |  | $ 2 |  |  | 420,434 |  |  | (350,861) | (40)
Balance (shares) at Mar. 31, 2020 |  |  |  | 15,375,282 |  |  |  |  |  |  |
CHANGES DURING THE PERIOD: |  |  |  |  |  |  |  |  |  |  |
Comprehensive (loss) income | (167,400) |  |  |  |  |  |  |  |  | (167,440) | 40
Exercise of options, vesting of restricted stock units and shares issued under employee stock purchase plan | (43) |  |  |  |  |  | (43) |  |  |  |
Exercise of options, vesting of restricted stock units and shares issued under employee stock purchase plan (in shares) |  |  |  | 132,692 |  |  |  |  |  |  |
Stock-based compensation | 10,768 |  |  |  |  |  | 10,768 |  |  |  |
Classification of stock awards to derivative liability | 657 |  |  |  |  |  | 657 |  |  |  |
Issuance of common stock, net of issuance costs |  |  | 53,649 | $ 1 |  |  |  |  | 53,648 |  |
Issuance of common stock, net of issuance costs (in shares) |  |  |  |  |  | 7,776,875 |  |  |  |  |
Issuance of stock related to merger | 104,362 |  |  | $ 1 |  |  | 104,361 |  |  |  |
Issuance of stock related to merger (in shares) |  |  |  | 18,636,103 |  |  |  |  |  |  |
Balance at Jun. 30, 2020 | 71,528 |  |  | $ 4 |  |  | 589,825 |  |  | (518,301) | $ 0
Balance (shares) at Jun. 30, 2020 |  |  |  | 41,920,952 |  |  |  |  |  |  |
Balance at Dec. 31, 2020 | $ 37,493 |  |  | $ 4 |  |  | 603,685 |  |  | (566,196) |
Balance (shares) at Dec. 31, 2020 | 43,205,221 |  |  | 43,205,221 |  |  |  |  |  |  |
CHANGES DURING THE PERIOD: |  |  |  |  |  |  |  |  |  |  |
Comprehensive (loss) income | $ (40,474) |  |  |  |  |  |  |  |  | (40,474) |
Exercise of options, vesting of restricted stock units and shares issued under employee stock purchase plan | 403 |  |  |  |  |  | 403 |  |  |  |
Exercise of options, vesting of restricted stock units and shares issued under employee stock purchase plan (in shares) |  |  |  | 254,351 |  |  |  |  |  |  |
Stock-based compensation | 4,343 |  |  |  |  |  | 4,343 |  |  |  |
Issuance of common stock, net of issuance costs |  | $ 26,304 | $ 46,824 | $ 1 |  |  |  | $ 26,304 | $ 46,823 |  |
Issuance of common stock, net of issuance costs (in shares) |  |  |  |  | 2,778,012 | 5,274,261 |  |  |  |  |
Balance at Jun. 30, 2021 | $ 74,893 |  |  | $ 5 |  |  | 681,558 |  |  | (606,670) |
Balance (shares) at Jun. 30, 2021 | 51,511,845 |  |  | 51,511,845 |  |  |  |  |  |  |
Balance at Mar. 31, 2021 | $ 92,901 |  |  | $ 5 |  |  | 679,642 |  |  | (586,746) |
Balance (shares) at Mar. 31, 2021 |  |  |  | 51,386,596 |  |  |  |  |  |  |
CHANGES DURING THE PERIOD: |  |  |  |  |  |  |  |  |  |  |
Comprehensive (loss) income | (19,924) |  |  |  |  |  |  |  |  | (19,924) |
Exercise of options, vesting of restricted stock units and shares issued under employee stock purchase plan | 15 |  |  |  |  |  | 15 |  |  |  |
Exercise of options, vesting of restricted stock units and shares issued under employee stock purchase plan (in shares) |  |  |  | 125,249 |  |  |  |  |  |  |
Stock-based compensation | 1,901 |  |  |  |  |  | 1,901 |  |  |  |
Balance at Jun. 30, 2021 | $ 74,893 |  |  | $ 5 |  |  | $ 681,558 |  |  | $ (606,670) |
Balance (shares) at Jun. 30, 2021 | 51,511,845 |  |  | 51,511,845 |  |  |  |  |  |  |

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