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NATURE OF OPERATIONS (Details) £ in Thousands |  |  |  |  |  | 3 Months Ended | 9 Months Ended | 12 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Mar. 31, 2022 USD ($) | Mar. 15, 2022 USD ($) | Jan. 12, 2022 USD ($) | Aug. 06, 2021 USD ($) | Feb. 12, 2021 shares | Sep. 30, 2022 USD ($) shares | Sep. 30, 2021 USD ($) | Sep. 30, 2022 USD ($) segment shares | Sep. 30, 2021 USD ($) | Dec. 31, 2021 USD ($) employee shares | Jun. 28, 2022 USD ($) | Jun. 28, 2022 GBP (£) | Jun. 15, 2022 USD ($) | Jun. 15, 2022 GBP (£) | Feb. 11, 2021 shares | Dec. 31, 2020 USD ($)
Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of segments | segment |  |  |  |  |  |  |  | 1 |  |  |  |  |  |  |  |
Additional paid-in capital |  |  |  |  |  | $ 692,853,000 |  | $ 692,853,000 |  | $ 688,156,000 |  |  |  |  |  |
Period of closing transaction |  |  | 1 year |  |  |  |  |  |  |  |  |  |  |  |  |
Disposal group, milestone payments receivable upon achievement of net sales |  |  | $ 450,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Milestone payments upon achieving certain criteria, exceeding annual net sales |  |  | $ 100,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring and related cost, number of positions eliminated | employee |  |  |  |  |  |  |  |  |  | 28 |  |  |  |  |  |
Reverse stock split, conversion ratio (share/share) |  |  |  |  | 0.25 |  |  |  |  |  |  |  |  |  |  |
Common stock shares authorized (in shares) | shares |  |  |  |  | 75,000,000 | 150,000,000 |  | 150,000,000 |  | 150,000,000 |  |  |  |  |  |
Net loss |  |  |  |  |  | $ (9,459,000) | $ (21,285,000) | $ (13,265,000) | $ (61,759,000) |  |  |  |  |  |  |
Cash used in operations |  |  |  |  |  |  |  | (25,325,000) | (46,349,000) |  |  |  |  |  |  |
(Loss) income from discontinued operations, net of income taxes |  |  |  |  |  | (204,000) | (7,009,000) | 12,919,000 | (25,923,000) |  |  |  |  |  |  |
Net loss |  |  |  |  |  | (9,255,000) | (14,276,000) | (26,184,000) | (35,836,000) |  |  |  |  |  |  |
Cash and cash equivalents, and restricted cash |  |  |  |  |  | 35,577,000 | $ 52,911,000 | 35,577,000 | $ 52,911,000 | $ 42,855,000 |  |  |  |  |  | $ 58,418,000
Accumulated deficit |  |  |  |  |  | (652,790,000) |  | (652,790,000) |  | $ (639,525,000) |  |  |  |  |  |
Outstanding debt |  |  |  |  |  | 0 |  | 0 |  |  |  |  |  |  |  |
Sale of stock, public float threshold |  |  |  |  |  | 75,000,000 |  | 75,000,000 |  |  |  |  |  |  |  |
Lincoln Park Equity Purchase Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration receivable on transaction | $ 30,000,000 | $ 30,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Term of equity purchase agreement | 36 months | 36 months |  |  |  |  |  |  |  |  |  |  |  |  |  |
Menlo - Premerger |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock shares authorized (in shares) | shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 300,000,000 |
MST Franchise | Discontinued Operations, Disposed of by Sale |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash proceeds |  |  |  |  |  | 20,000,000 |  | 20,000,000 |  |  |  |  |  |  |  |
Additional paid-in capital |  |  |  |  |  | $ 5,000,000 |  | $ 5,000,000 |  |  |  |  |  |  |  |
Licensing Agreements |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments for licensing agreements |  |  |  | $ 1,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Royalty percent, maximum |  |  |  | 10.00% |  |  |  |  |  |  |  |  |  |  |  |
Topical BETi Option Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments for licensing agreements |  |  |  | $ 500,000 |  |  |  |  |  |  |  |  |  |  |  |
Milestone payments upon achieving certain criteria, maximum |  |  |  | $ 15,750,000 |  |  |  |  |  |  |  |  |  |  |  |
Royalty payments as percentage of annual net sales of licensed product (percent) |  |  |  | 10.00% |  |  |  |  |  |  |  |  |  |  |  |
Oral BETi Option Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments for licensing agreements |  |  |  | $ 4,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Milestone payments upon achieving certain criteria, maximum |  |  |  | $ 43,750,000 |  |  |  |  |  |  |  |  |  |  |  |
First payments for licensing agreements |  |  |  |  |  |  |  |  |  |  | $ 386,366 | £ 300 |  |  |  |
Second payment for licensing agreements |  |  |  |  |  |  |  |  |  |  |  |  | $ 997,407 | £ 850 |  |

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