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NATURE OF OPERATIONS (Details)
 1 Months Ended 3 Months Ended 9 Months Ended
Oct. 30, 2023
Feb. 10, 2023
Jan. 12, 2023
USD ($)
Mar. 31, 2022
USD ($)
Mar. 15, 2022
USD ($)
Nov. 30, 2023
USD ($)
Jan. 31, 2023
Sep. 30, 2023
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2023
USD ($)
segment
Sep. 30, 2022
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items]                          
Clinical improvement scoring index, cohort 1 (percent)             1.00%            
Number of reportable segments | segment                   1      
Reverse stock split ratio   0.0556                      
Net loss               $ 6,584,000 $ 9,459,000 $ 22,264,000 $ 13,265,000    
Cash used in operations                   20,204,000 24,389,000    
Cash and investments               15,502,000 $ 35,577,000 15,502,000 35,577,000 $ 30,975,000 $ 42,855,000
Accumulated Deficit               685,148,000   685,148,000   $ 662,735,000  
Deferred payment received from sale of MST Franchise     $ 5,000,000             5,000,000 $ 15,666,000    
Debt outstanding               $ 0   $ 0      
Subsequent Event                          
Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items]                          
Clinical improvement scoring index, cohort2 (percent) 2.00%                        
Lincoln Park Equity Purchase Agreement                          
Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items]                          
Consideration receivable on transaction       $ 30,000,000 $ 30,000,000                
Term of equity purchase agreement       36 months 36 months                
Private Placement | Subsequent Event                          
Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items]                          
Gross proceeds           $ 88,200,000