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Note 3 - Summary of Significant Accounting Policies (Details Textual) - USD ($)
3 Months Ended 9 Months Ended
Feb. 12, 2016
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Private Placement [Member] | Series B Preferred Stock [Member] | Placement Agent Warrants [Member]          
Class of Warrant or Right, Issued 127,346        
Private Placement [Member] | Series B Preferred Stock [Member] | Strategic Bio Partners [Member] | Debt Settlement [Member]          
Class of Warrant or Right, Issued 295,945        
Options and Warrants [Member]          
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount       6,418,887 4,801,112
Convertible Preferred Shares [Member]          
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount       2,796,929 0
Goodwill, Fair Value Disclosure $ 0        
Fair Value Assumptions, Expected Dividend Rate   0.00%      
Derivative, Gain (Loss) on Derivative, Net   $ (938) $ (29,332)
Goodwill, Impairment Loss   $ 404,169
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount       9,215,816 4,801,112