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Note 3 - Summary of Significant Accounting Policies (Details Textual) - USD ($)
3 Months Ended 6 Months Ended 12 Months Ended
Feb. 12, 2016
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Dec. 31, 2015
Dec. 31, 2014
Private Placement [Member] | Series B Preferred Stock [Member] | Placement Agent Warrants [Member]              
Class of Warrant or Right, Issued 127,346            
Private Placement [Member] | Series B Preferred Stock [Member] | Strategic Bio Partners [Member] | Debt Settlement [Member]              
Class of Warrant or Right, Issued 295,945            
Options and Warrants [Member]              
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount       6,418,887 4,801,112 5,111,111 4,371,111
Convertible Preferred Shares [Member]              
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount       11,018,766 0    
Goodwill, Fair Value Disclosure $ 0            
Fair Value Assumptions, Expected Dividend Rate   0.00%          
Derivative, Gain (Loss) on Derivative, Net   $ (26,887) $ (28,394)    
Goodwill, Impairment Loss   $ 404,169    
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount       17,437,653 4,801,112