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Note 7 - Stockholders' Equity (Deficit) (Details Textual) |  |  |  |  | 12 Months Ended
--- | --- | --- | --- | --- | ---
Dec. 31, 2016 USD ($) $ / shares shares | Oct. 26, 2016 $ / shares shares | Apr. 15, 2016 $ / shares shares | Feb. 12, 2016 USD ($) $ / shares shares | Dec. 31, 2016 USD ($) $ / shares shares | Dec. 31, 2015 USD ($) $ / shares shares
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number | 2,484,445 |  |  |  | 2,484,445 |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price | $ / shares | $ 1.04 |  |  |  | $ 1.04 |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value | $ | $ 697,820 |  |  |  | $ 697,820 |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross |  |  |  |  | 1,308,300 |
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares |  |  |  |  | $ 1.25 |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Number of Shares |  |  |  |  | 1,272,982 |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period |  |  |  |  | 25,000 |
Stock Issued During Period, Value, Stock Options Exercised | $ |  |  |  |  | $ 6,500 |
Class of Warrant or Right, Outstanding | 3,826,658 |  |  |  | 3,826,658 | 3,403,367
Class of Warrant or Right, Outstanding, Weighted Average Exercise Price | $ / shares | $ 1.07 |  |  |  | $ 1.07 | $ 1.03
Class of Warrant or Right Outstanding, Aggregate Intrinsic Value | $ | $ 763,342 |  |  |  | $ 763,342 |
Predecessor Warrants [Member] | Series B Preferred Stock [Member] |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights |  |  |  | 295,945 |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares |  |  |  | $ 1.25 |  |
Private Placement [Member] | Series B Preferred Stock [Member] |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights |  |  |  | 423,291 |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares |  |  |  | $ 1.25 |  |
Class of Warrant or Right, Expiration Period |  |  |  | 5 years |  |
Private Placement [Member] | Placement Agent Warrants [Member] |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares |  |  | $ 1.25 |  |  |
Private Placement [Member] | Placement Agent Warrants [Member] | Series B Preferred Stock [Member] |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights |  |  | 127,346 |  |  |
Protagenic Therapeutics Inc [Member] |  |  |  |  |  |
Business Combination, Stock Warrant Conversion Ratio |  |  |  | 1 |  |
Debt Instrument, Face Amount | $ |  |  |  | $ 665,000 |  |
Debt Instrument, Increase, Accrued Interest | $ |  |  |  | $ 35,000 |  |
Protagenic Therapeutics Inc [Member] | Predecessor Warrants [Member] |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights |  |  |  | 295,945 |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares |  |  |  | $ 1.25 |  |
Class of Warrant or Right, Expiration Period |  |  |  | 5 years |  |
Protagenic Therapeutics Inc [Member] | Placement Agent Warrants [Member] |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights |  |  |  | 127,346 |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares |  |  |  | $ 1.25 |  |
Protagenic Therapeutics Inc [Member] | Private Placement [Member] |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights |  |  |  | 3,403,367 |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares |  |  |  | $ 1.05 |  |
Each Member of Board of Directors [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross |  |  | 40,000 |  |  |
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares |  |  | $ 1.25 |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Additional |  |  | 5,000 |  |  |
Director [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross |  |  | 175,000 |  |  |
Employees and Consultants [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross |  |  | 1,009,300 |  |  |
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares |  |  | $ 1.25 |  |  |
Share-based Compensation Arrangement By Share-based Payment Award, Options, Grants in Period, Grant Date Fair Value | $ | 1,261,625 |  |  |  |  |
Former Executives [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period |  |  |  |  | 3 years |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross |  |  |  |  | 17,785 |
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares |  |  |  |  | $ 1.25 |
Share-based Compensation Arrangement By Share-based Payment Award, Options, Grants in Period, Grant Date Fair Value | $ | $ 22,231 |  |  |  |  |
Employee [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period |  | 4 years |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period |  | 10 years |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross |  | 25,000 |  |  |  |
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares |  | $ 1.25 |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Cliff Vesting Period |  | 1 year |  |  |  |
Employee Stock Option [Member] |  |  |  |  |  |
Allocated Share-based Compensation Expense | $ |  |  |  |  | $ 546,134 | $ 477,868
Employee Stock Option [Member] | Each Member of Board of Directors [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period |  |  | 2 years |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period |  |  | 10 years |  |  |
Employee Stock Option [Member] | Employees and Consultants [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period |  |  | 4 years |  |  |
Employee Stock Option [Member] | Minimum [Member] | Employees and Consultants [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period |  |  | 10 years |  |  |
Employee Stock Option [Member] | Maximum [Member] | Employees and Consultants [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period |  |  | 1 year |  |  |
The 2006 Plan [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number | 2,484,445 |  |  |  | 2,484,445 | 1,707,744
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price | $ / shares | $ 1.18 |  |  |  | $ 1.18 | $ 0.84
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross |  |  |  |  | 1,193,300 |
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares |  |  |  |  | $ 1.25 |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period |  |  |  |  | 25,000 |
The 2006 Plan [Member] | Chief Financial Officer [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross |  |  |  | 100,000 |  |
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares |  |  |  | $ 1.25 |  |
The 2006 Plan [Member] | Employee Stock Option [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized | 2,000,000 |  |  |  | 2,000,000 |
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period |  |  |  |  | 10 years |
The 2006 Plan [Member] | Employee Stock Option [Member] | Chief Financial Officer [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period |  |  |  | 3 years |  |
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period |  |  |  | 10 years |  |
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting, Number of Monthly Installments |  |  |  | 35 |  |
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting, Monthly Installment, Shares |  |  |  | 0.18 |  |
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting, Final Monthly Installment, Shares |  |  |  | 2,778 |  |
Allocated Share-based Compensation Expense | $ |  |  |  |  | $ 25,696 |
The 2006 Plan [Member] | Employee Stock Option [Member] | Minimum [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period |  |  |  |  | 1 year |
The 2006 Plan [Member] | Employee Stock Option [Member] | Maximum [Member] |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period |  |  |  |  | 5 years |

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