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Note 3 - Summary of Significant Accounting Policies - Antidilutive Securities Excluded From Computation of Earnings Per Share (Details) - shares
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Common shares issuable under the conversion feature of preferred shares (in shares) 7,183,869 5,051,111
Convertible Preferred Shares [Member]    
Common shares issuable under the conversion feature of preferred shares (in shares) 872,766
Employee Stock Option [Member]    
Common shares issuable under the conversion feature of preferred shares (in shares) 2,484,445 1,707,744
Warrant [Member]    
Common shares issuable under the conversion feature of preferred shares (in shares) 3,826,658 3,403,367