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Note 6 - Stockholders' Equity (Details Textual)
3 Months Ended
Feb. 12, 2016
USD ($)
$ / shares
shares
Mar. 31, 2017
USD ($)
$ / shares
shares
Mar. 31, 2016
USD ($)
$ / shares
shares
Dec. 31, 2016
USD ($)
$ / shares
shares
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value | $   $ 166,250   $ 171,537
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross   150,000 161,582  
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares   $ 1.25 $ 1.25  
Class of Warrant or Right, Outstanding   3,726,658   3,826,658
Class of Warrant or Right, Outstanding, Weighted Average Exercise Price | $ / shares   $ 1.05   $ 1.02
Class of Warrant or Right Outstanding, Aggregate Intrinsic Value | $   $ 763,342    
Private Placement [Member] | Series B Preferred Stock [Member]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights 423,291      
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares $ 1.25      
Class of Warrant or Right, Expiration Period 5 years      
Protagenic Therapeutics Inc [Member]        
Business Combination, Stock Warrant Conversion Ratio 1      
Debt Instrument, Face Amount | $ $ 665,000      
Debt Instrument, Increase, Accrued Interest | $ $ 35,000      
Protagenic Therapeutics Inc [Member] | Predecessor Warrants [Member]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights 295,945      
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares $ 1.25      
Class of Warrant or Right, Expiration Period 5 years      
Protagenic Therapeutics Inc [Member] | Placement Agent Warrants [Member]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights 127,346      
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares $ 1.25      
Protagenic Therapeutics Inc [Member] | Private Placement [Member]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights 3,403,367      
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares $ 1.05      
Employee Stock Option [Member]        
Allocated Share-based Compensation Expense | $   $ 355,336 $ 102,908  
The 2006 Plan [Member]        
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number   2,613,299   2,484,445
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross   150,000    
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares   $ 1.25    
The 2006 Plan [Member] | Employee Stock Option [Member]        
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized   2,000,000    
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period   10 years    
The 2006 Plan [Member] | Employee Stock Option [Member] | Minimum [Member]        
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period   1 year    
The 2006 Plan [Member] | Employee Stock Option [Member] | Maximum [Member]        
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period   5 years