Options expiration date, description.

No definition available.

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- Definition

The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 985
-SubTopic 20
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6501960&loc=d3e128462-111756

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 730
-SubTopic 10
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6420194&loc=d3e21568-108373

+ Details

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- Definition

The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (c)(1)(iii)
-URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901

+ Details

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Period Type:	instant

- Definition

Net number of share options (or share units) granted during the period.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (c)(1)(iv)(1)
-URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901

+ Details

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- Definition

Period from grant date that an equity-based award expires, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (a)(2)
-URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901

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Period Type:	duration

- Definition

Number of options vested.

+ References

No definition available.

+ Details

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- Details

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- Details

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- Details

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- Details

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- Details

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Collaborative Agreements (Details Narrative) - USD ($)	12 Months Ended
Collaborative Agreements (Details Narrative) - USD ($)	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2015
Share-based compensation weighted average exercise price
Number of stock options vested	972,651	800,456
Research and development expense	$ 881,186	$ 717,452
Research Agreement [Member]
Research and development expense	$ 107,868	$ 93,919
University of Toronto [Member]
Share-based compensation stock options, grants			25,000
Share-based compensation weighted average exercise price			$ 1.00
Share-based payment award, expiration period			10 years
Dr. Lovejoy [Member] \| Employee Stock Option [Member]
Share-based compensation stock options, grants	533,299
Share-based compensation weighted average exercise price	$ 1.00
Number of stock options vested	457,901
Options expiration date, description	on March 30, 2021, December 1, 2022, April 15, 2026, March 1, 2027 or on October 16, 2027.
Dr. Lovejoy [Member] \| Employee Stock Option [Member] \| Minimum [Member]
Share-based compensation weighted average exercise price	$ 1.25
Share-based payment award, expiration period	10 years
Dr. Lovejoy [Member] \| Employee Stock Option [Member] \| Maximum [Member]
Share-based compensation weighted average exercise price	$ 1.75
Share-based payment award, expiration period	13 years