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Collaborative Agreements (Details Narrative) - USD ($) |  | 12 Months Ended
--- | --- | ---
Feb. 25, 2019 | Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2015
Number of stock options vested |  | 1,104,044 | 584,895 |
Research and development expense |  | $ 699,797 | $ 807,947 |
Research Agreements [Member] |  |  |  |
Research and development expense |  | $ 0 | $ 63,905 |
Stock Options [Member] |  |  |  |
Number of stock options vested | 59,900 |  |  |
University of Toronto [Member] |  |  |  |
Share-based compensation stock options, grants |  |  |  | 25,000
Share-based compensation weighted average exercise price |  |  |  | $ 1.00
Share-based payment award, expiration period |  |  |  | 10 years
Options expiration date, description |  |  |  | Exercisable over a ten year period which ends on April 1, 2022.
Dr. David Lovejoy [Member] | Stock Options [Member] |  |  |  |
Share-based compensation stock options, grants |  | 553,299 |  |
Share-based compensation weighted average exercise price |  | $ 1.00 |  |
Options expiration date, description |  | These have an exercise price of $1.00, $1.25 or 1.75 and are exercisable over ten or thirteen year periods which end either on March 30, 2021, December 1, 2022, April 15, 2026, March 1, 2027, October 16, 2027 or on February 13, 2030. |  |
Number of stock options vested |  | 527,570 |  |
Dr. David Lovejoy [Member] | Stock Options [Member] | Minimum [Member] |  |  |  |
Share-based compensation weighted average exercise price |  | $ 1.25 |  |
Share-based payment award, expiration period |  | 10 years |  |
Dr. David Lovejoy [Member] | Stock Options [Member] | Maximum [Member] |  |  |  |
Share-based compensation weighted average exercise price |  | $ 1.75 |  |
Share-based payment award, expiration period |  | 13 years |  |

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- Definition The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 985 -SubTopic 20 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6501960&loc=d3e128462-111756 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 730 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6420194&loc=d3e21568-108373 + Details
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- Definition The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iii) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Net number of share options (or share units) granted during the period. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iv)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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