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COLLABORATIVE AGREEMENTS (Details Narrative) - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2015
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Number of stock options vested 92,812    
Research and development expense $ 669,838 $ 592,351  
Research Agreements [Member]      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Research and development expense $ 0 $ 0  
University of Toronto [Member]      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Share-based compensation stock options, grants     25,000
Share-based compensation weighted average exercise price     $ 1.00
Share-based payment award, expiration period     10 years
Dr. David Lovejoy [Member] | Share-Based Payment Arrangement, Option [Member]      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Share-based compensation stock options, grants 553,299    
Number of stock options vested 442,882    
Number of stock options expired 100,000    
Options expiration date, description These have an exercise price of $1.00, $1.25 or 1.75 and are exercisable over ten or thirteen year periods which end either on March 30, 2021, December 1, 2022, April 15, 2026, March 1, 2027, October 16, 2027 or on February 13, 2030