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Class of warrant or right, outstanding, intrinsic value.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

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Weighted-average period over which cost not yet recognized is expected to be recognized for award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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Amount of cost to be recognized for option under share-based payment arrangement.

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Number of equity instruments other than options outstanding, including both vested and non-vested instruments.

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Gross number of share options (or share units) granted during the period.

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Amount by which the current fair value of the underlying stock exceeds the exercise price of options outstanding.

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Number of options outstanding, including both vested and non-vested options.

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Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan.

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Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options.

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Reduction in the number of shares during the period as a result of a reverse stock split.

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STOCKHOLDERS’ DEFICIT (Details Narrative) - USD ($)			3 Months Ended
STOCKHOLDERS’ DEFICIT (Details Narrative) - USD ($)	Jan. 01, 2022	Jan. 01, 2021	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2022
Accumulated Other Comprehensive Income (Loss) [Line Items]
Stock options outstanding			1,357,466
Stock options outstanding weighted average exercise price			$ 7.39
Stock options. intrinsic value			$ 0
Number of options granted, shares
Employees [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Share based compensation expense			$ 1,713	$ 48,828
Unamortized stock option expense			6,853
Non-Employees [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Share based compensation expense			164,994	$ 166,518
Unamortized stock option expense			$ 1,169,113
Share-Based Payment Arrangement, Option [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Stock options outstanding			1,357,466		1,357,466
Stock options outstanding weighted average exercise price			$ 7.39		$ 7.39
Number of options granted, shares			(0)	50,000
Options, exercise price per share			$ 4.84
Share based compensation expense			$ 166,707	$ 215,346
Unamortized stock option expense			$ 1,175,966
Weighted average period for unamortized stock compensation (in years)			3 years 7 months 9 days
Share-Based Payment Arrangement, Option [Member] \| General and Administrative Expense [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Share based compensation expense			$ 51,526	176,949
Share-Based Payment Arrangement, Option [Member] \| Research and Development Expense [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Share based compensation expense			$ 115,181	38,397
2016 Plan [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Number of additional shares granted	184,260	142,457
Number of shares available for grant			1,543,872		1,543,872
Common Stock [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Rounding of shares related to a reverse stock split			9,644
Warrant [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Share based compensation expense			$ 0	$ 20,433
Warrant shares, outstanding			1,055,066		1,537,158
Warrant exercise price			$ 17.82
Class of warrant or right, outstanding, intrinsic value			$ 0